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Director Infrastructure Architecture Jobs (NOW HIRING)

We are seeking an IT Infrastructure Architecture Leader (Senior Manager or Associate Director) to join our IOPS IT team, ensuring the reliable operation and strategic development of IT and ...

$200 - $250/hr

The Senior Director of Infrastructure and Cloud Engineering is a senior technology leader ... Establish infrastructure and cloud governance, standards, roadmaps, architecture patterns ...

Reporting to the AVP, Enterprise Infrastructure and Operations, the Senior Director of ... This role will lead a high-performing team of Technical Analysts and Architects who design and ...

Direct infrastructure lifecycle planning, modernization strategies, and technology refresh roadmaps ... Develop and modernize enterprise network architecture to support operational growth and digital ...

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Director Infrastructure Architecture information

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$70K

$153.7K

$227.5K

How much do director infrastructure architecture jobs pay per year?

As of Sep 9, 2026, the average yearly pay for director infrastructure architecture in the United States is $153,682.00, according to ZipRecruiter salary data. Most workers in this role earn between $115,500.00 and $187,500.00 per year, depending on experience, location, and employer.

What does a director of infrastructure architecture do?

A Director of Infrastructure Architecture is responsible for overseeing the design, implementation, and management of an organization's IT infrastructure. This role involves developing long-term strategies for network, storage, and server systems to ensure scalability, reliability, and security. The director collaborates with other IT leaders to align infrastructure initiatives with business goals and often manages a team of architects and engineers. Key responsibilities include setting standards, evaluating new technologies, and ensuring compliance with regulations and best practices.

What are the key skills and qualifications needed to thrive as a director of infrastructure architecture?

To thrive as a Director of Infrastructure Architecture, you need deep expertise in IT infrastructure design, cloud computing, and enterprise architecture, typically supported by a bachelor's or master's degree in computer science or a related field. Familiarity with tools like AWS, Azure, VMware, and certifications such as TOGAF or AWS Certified Solutions Architect are commonly required. Leadership, strategic thinking, and strong communication skills set standout candidates apart in this role. These skills are vital to ensure robust, scalable technology solutions that align with business goals and enable organizational growth.

What are some common challenges faced by a director of infrastructure architecture, and how are they typically addressed?

A Director of Infrastructure Architecture often faces challenges such as managing complex, legacy systems while implementing new technologies, ensuring security and compliance across all platforms, and aligning infrastructure strategy with overall business goals. To address these, directors frequently collaborate with cross-functional teams, adopt standardized frameworks, and invest in continuous learning for themselves and their teams. Strong change management and communication skills are essential to successfully lead large-scale infrastructure transformations and to gain buy-in from stakeholders throughout the organization.

What cities are hiring for Director Infrastructure Architecture jobs?

Cities with the most Director Infrastructure Architecture job openings:

What states have the most Director Infrastructure Architecture jobs?

States with the most job openings for Director Infrastructure Architecture jobs include:

What are popular job titles related to Director Infrastructure Architecture jobs?

For Director Infrastructure Architecture jobs, the most frequently searched job titles are:

Infographic showing various Director Infrastructure Architecture job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 83% Full Time, 13% Part Time, 1% Temporary, and 2% Contract. Highlights an 92% Physical, 3% Hybrid, and 5% Remote job distribution, with an average salary of $153,682 per year, or $73.9 per hour.

Director of GMP IT Operations, Infrastructure Architecture

Regeneron Pharmaceuticals
Biotechnology Research and Development • 5 - 10K employees

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 2 days ago


Key responsibilities

  • Define, implement, and lead IT/OT infrastructure architecture across networking, compute, and security domains.

  • Ensure reliable operation of IT/OT infrastructure, including data center operations, network services, and asset management.

  • Manage service providers, oversee incident escalation, and report on IT operations performance.


Regeneron rating

8.5

Company rating: 8.5 out of 10

Based on 44 frontline employees who took The Breakroom Quiz

19th of 86 rated pharmaceutical


Job description

Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking an IT Infrastructure Architecture Leader (Senior Manager or Associate Director) to join our IOPS IT team, ensuring the reliable operation and strategic development of IT and Operational Technology infrastructure across our GxP manufacturing environment. In this role, you will define and lead infrastructure architecture - spanning hyper-converged systems, advanced networking, and wireless technologies - while collaborating with corporate IT, automation teams, service providers, and cross-functional partners to maintain secure, scalable, and compliant operations. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:
  • Location: Troy, New York, United States
  • Work model: Monday - Friday 8am -4:30pm
Discover your role:
  • Define, implement, and lead IT/OT infrastructure architecture with a focus on hyper-converged systems, advanced networking, and wireless technologies; design and document infrastructure architecture across networking, compute, and security domains
  • Ensure reliable operation of IT/OT infrastructure including servers, hardware, communications, and desktop support; provide operational oversight for data centre operations, network services, telecom, and asset management
  • Build scalable and secure wireless networks to support industrial and enterprise needs; maintain robust security measures including data integrity and disaster recovery planning
  • Apply security frameworks such as NIST CSF, IEC 62443, or ISO 27001 within a regulated environment; maintain compliance with automation system standards including DeltaV/Emerson and Rockwell/Allen-Bradley
  • Ensure compliance with GxP, FDA, and global regulatory requirements; ensure systems and procedures support effective monitoring, reporting, and audit readiness
  • Manage service providers to ensure high-quality delivery aligned to SLAs; act as escalation point for major incidents and provide regular management reporting on service performance and IT operations
  • Collaborate with corporate IT and OT partners to ensure seamless system integration and alignment across the enterprise
  • Lead, mentor, and develop a diverse technical team spanning Helpdesk, Desktop, Server, and Network functions; oversee recruitment, training, performance evaluations, and goal setting for the IT Operations team
  • Hands-on experience designing and documenting infrastructure architecture across networking, compute, and security domains required
  • Demonstrated experience with security frameworks such as NIST CSF, IEC 62443, or ISO 27001 and applying them within regulated environments
  • Demonstrated experience managing diverse technical teams including Helpdesk, Desktop, Server, and Network staff; experience managing vendors and managed service providers required
  • Experience developing and deploying SLAs, metrics, and operational best practices; proven track record implementing ITIL practices within an organization
  • Strong background in Microsoft OS including Server and GPO elements; strong understanding of data integrity and associated tools
  • Experience with Business Continuity and Disaster Recovery planning required
  • Knowledge of IT compliance guidelines including PIC/S, 21 CFR Part 11, Annex 11, and GAMP preferred
This role requires:
  • BS/BA in Information Technology or a related field
  • Associate Director: 10 years of progressively more responsible experience, including 8 years of management experience and a minimum of 3 years' experience in an FDA or similarly regulated environment
  • Director: 12 years of progressively more responsible experience, including 10 years of management experience and a minimum of 4 years' experience in an FDA or similarly regulated environment
  • May consider equivalent combination of education and experience. Level is determined based on qualifications relevant to the role

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.


Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed onsite. Please speak with your recruiter and hiring manager for more information about onsite expectations for your role and location.


As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.


For jobs in Canada: this posting is for an existing position.


Salary Range (annually)

$147,800.00 - $286,900.00

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