ZipRecruiter

Log In

1

Director Clinical Transformation Jobs (NOW HIRING)

Smith & Nephew

Director, Clinical Data & AI

Andover, MA · On-site

The Director of Clinical Data & AI is the global functional leader responsible for the strategy ... Data pipelines, transformation, and interoperability frameworks * Ensure scalable, compliant, and ...

Mercy

Executive Director Clinical Innovation

$81K - $111K/yr

The Executive Director of Clinical Innovation is a visionary clinical leader responsible for ... Minimum of 5 years of progressive leadership experience in clinical operations or transformation.

Olema Oncology

Director, Clinical Science

San Francisco, CA · On-site

$94K - $128K/yr

It's an exciting time to be part of Team Olema, with our transformation into a fully integrated ... About the Role >>> Director, Clinical Science As the Director, Clinical Sciencereporting to the ...

Olema Oncology

Director, Clinical Science

Boston, MA · On-site

$86K - $118K/yr

It's an exciting time to be part of Team Olema, with our transformation into a fully integrated ... About the Role >>> Director, Clinical Science As the Director, Clinical Sciencereporting to the ...

InnovAge

Director, Clinical Applications

Denver, CO · On-site +1

$159K - $215K/yr

As a trusted thought partner to clinical and operational leadership, the Director drives technology-enabled care transformation, leveraging AI, interoperability, and data-driven workflows to support ...

InnovAge

Director, Clinical Applications

Denver, CO

As a trusted thought partner to clinical and operational leadership, the Director drives technology-enabled care transformation, leveraging AI, interoperability, and data-driven workflows to support ...

InnovAge

Director, Clinical Applications

Denver, CO

$159K - $270K/yr

As a trusted thought partner to clinical and operational leadership, the Director drives technology-enabled care transformation, leveraging AI, interoperability, and data-driven workflows to support ...

previous pagenext page

Showing results 21-40

All JobsClinical Transformation JobsDirector Clinical Transformation Jobs

Director Clinical Transformation information

See salary details

$51.5K

$100.1K

$167K

How much do director clinical transformation jobs pay per year?

As of Aug 7, 2026, the average yearly pay for director clinical transformation in the United States is $100,124.00, according to ZipRecruiter salary data. Most workers in this role earn between $80,000.00 and $109,000.00 per year, depending on experience, location, and employer.

What is a director clinical transformation?

A Director of Clinical Transformation leads initiatives to improve healthcare quality, efficiency, and patient outcomes by implementing innovative processes, technologies, and best practices. They collaborate with clinical and administrative teams to drive organizational change, enhance care delivery models, and ensure alignment with regulatory standards. This role requires expertise in healthcare operations, data analytics, and change management to support continuous improvement efforts and optimize patient care.

What are the typical challenges faced by a director clinical transformation, and how do they impact daily work?

Directors of Clinical Transformation often encounter challenges such as resistance to change among clinical staff, aligning diverse stakeholders on new processes, and integrating new technologies into existing workflows. These challenges require strategic planning, effective change management techniques, and ongoing communication to ensure buy-in across departments. On a daily basis, you may need to facilitate meetings, troubleshoot implementation issues, and measure progress against performance metrics. Successfully navigating these obstacles supports smoother clinical operations and better patient outcomes, making the role both demanding and highly impactful.

What are the key skills and qualifications needed to thrive in the director clinical transformation position, and why are they important?

To thrive as a Director Clinical Transformation, you need deep experience in healthcare operations, project management, process improvement methodologies (such as Lean or Six Sigma), and a relevant advanced degree in nursing, healthcare administration, or a related field. Familiarity with healthcare IT systems, EHR platforms, data analytics tools, and certifications like PMP or CPHQ are often important. Outstanding leadership, strategic thinking, change management, and communication skills help you drive large-scale transformation initiatives and engage multidisciplinary teams. These competencies are crucial for successfully navigating the complexities of clinical practice while implementing sustainable improvements that enhance patient care and operational efficiency.

More about Director Clinical Transformation jobs
What cities are hiring for Director Clinical Transformation jobs? Cities with the most Director Clinical Transformation job openings:
What are the most commonly searched types of Clinical Transformation jobs? The most popular types of Clinical Transformation jobs are:
What states have the most Director Clinical Transformation jobs? States with the most job openings for Director Clinical Transformation jobs include:
What job categories do people searching Director Clinical Transformation jobs look for? The top searched job categories for Director Clinical Transformation jobs are:
Director Clinical Transformation jobs near you
Infographic showing various Director Clinical Transformation job openings in the United States as of August 2026, with employment types broken down into 3% As Needed, 72% Full Time, 17% Part Time, and 8% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $100,124 per year, or $48.1 per hour.

Director, Clinical Data & AI

Smith & Nephew

Andover, MA • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 25 days ago

Smith & Nephew rating

8.1

Company rating: 8.1 out of 10

Based on 41 frontline employees who took The Breakroom Quiz

113th of 536 rated manufacturers

Job description

Life Unlimited. At Smith+Nephew we design and manufacture technology that takes the limits off living. The Director of Clinical Data & AI is the global functional leader responsible for the strategy, architecture, and operational execution of clinical data and AI capabilities supporting end-to-end evidence generation. This role owns the clinical data lifecycle-from data acquisition and management to advanced analytics, AI enablement, and synthetic/simulated data-ensuring all data assets are high-quality, interoperable, and fit-for-purpose for regulatory, scientific, and operational decision-making. The Director serves as the enterprise authority on clinical data platforms and AI-enabled evidence generation, driving integration across clinical systems, data engineering, AI/ML, and statistical/clinical programming. This position has full accountability for the strategy, execution, quality, and evolution of the Clinical Data & AI function globally.
What will you be doing?
1. Global Clinical Data & AI Strategy
  • Define and execute the global strategy for Clinical Data & AI aligned to enterprise evidence-generation and AI transformation goals
  • Establish a unified operating model integrating:
    • Clinical systems (EDC, eCOA, registries)
    • Clinical Data Lake & central data model
    • Data management and data engineering
    • AI/ML and advanced analytics
  • Serve as the enterprise authority on clinical data architecture and AI enablement for clinical & medical affairs across all BUs and geographies
  • Partner with Clinical Study Management, Clinical Strategy, Regulatory, Medical Affairs, Statistics, and IT to define data-driven evidence strategies

2. Clinical Data Architecture & Platforms
  • Own the design, governance, and evolution of:
    • Clinical Data Lake (CDL) and standardized data models
    • Clinical systems ecosystem (EDC, eCOA, registry ingestion, integrations)
    • Data pipelines, transformation, and interoperability frameworks
  • Ensure scalable, compliant, and extensible architecture supporting:
    • Cross-study analytics
    • Real-world data integration
    • Device + clinical data linkage
  • Drive standardization (e.g., CDISC-based models) and elimination of data silos

3. AI, Data Science & Advanced Analytics
  • Lead development and deployment of AI/ML capabilities across the clinical lifecycle, including:
    • Data quality automation and monitoring
    • AI-assisted clinical study reporting and analytics
    • Cross-study insights and meta-analyses
  • Drive integration of AI into core workflows, not point solutions
  • Establish best practices for:
    • Model development, validation, monitoring
    • Responsible AI (traceability, reproducibility, regulatory alignment)
  • Oversee collaboration between data science, statistics, and programming teams

4. Synthetic Data, Simulation & Virtual Twins
  • Own strategy and execution for:
    • Synthetic clinical data generation
    • Simulation frameworks for study design and operational planning
    • Virtual twin development for patient- and study-level modeling
  • Ensure alignment with regulatory expectations for transparency and scientific validity
  • Integrate synthetic and simulated data into:
    • Study design optimization
    • Evidence generation (e.g., hybrid designs, external controls)

5. Clinical Data Management & Quality
  • Oversee global clinical data management function, ensuring:
    • High-quality, consistent, and inspection-ready data
    • Efficient study startup (eCRF design, database builds) and closeout
    • Risk-based monitoring and analytics-driven data review
  • Embed AI, machine learning modeling, and automation into CDM workflows to improve efficiency and quality
  • Ensure alignment with regulatory and compliance standards (FDA, EU MDR, GDPR, HIPAA)

6. Statistical & Clinical Programming Integration
  • Own alignment and integration of:
    • Statistical programming (TFLs, ADaM outputs)
    • Clinical programming (data pipelines, transformations)
  • Ensure seamless data flow from raw data → analysis-ready datasets → reporting
  • Drive standardization, automation, and reuse across studies and programs
  • Leverage AI solutions to accelerate programming across Global Clinical and Medical Affairs

7. Operational Excellence & Delivery Model
  • Own intake, prioritization, and delivery across:
    • Data platform initiatives
    • AI/ML programs
    • Study-level data operations
  • Implement scalable delivery models for standardized multi-source clinical outcomes datasets from the Clinical Data Lake to key business stakeholder teams
  • Optimize resourcing across:
    • High-throughput standardized work
    • High-complexity AI/data science initiatives

8. Regulatory & Data Governance Leadership
  • Ensure all clinical data and AI activities are:
    • Compliant with global regulatory requirements
    • Traceable, auditable, and reproducible
  • Establish strong governance across:
    • Data standards and lineage
    • AI model lifecycle
    • Data privacy and security
  • Support regulatory submissions with robust, defensible data strategies

Key Interfaces
  • Global Clinical Research Operations leadership
  • Clinical / Medical Affairs / Regulatory Affairs
  • Statistics, Data Science, and AI teams
  • IT / Digital / Enterprise Data organizations
  • External partners, CROs, AI vendors, and regulators

Education
  • BA required, PhD (preferred) or Master's in Data Science, Biostatistics, Computer Science, or related field

What will you need to be successful?
  • Minimum of 10 years experience across clinical data, AI/ML, and data platforms in medtech/pharma/biotech
  • Proven leadership of multi-domain teams (data management, engineering, data science, AI, programming)
  • Demonstrated ownership of enterprise data architecture (e.g., data lake/platform) - Databricks preferred
  • Strong track record supporting regulatory submissions and clinical evidence generation
  • Enterprise mindset - integrates data, AI, and operations into a unified capability
  • Technical depth + breadth - credible across data engineering, CDM, AI, and analytics
  • Regulatory credibility - understands how data and AI decisions impact submissions
  • Execution rigor - delivers scalable, high-quality platforms and outputs
  • Transformational leadership - embeds AI into workflows, not as isolated innovation
  • Pragmatic innovation - advances capabilities while maintaining compliance and reliability

You Unlimited.
  • The anticipated base compensation range for this position is $165,250-$236,000 USD annually. The actual base pay offered to the successful candidate will be based on multiple factors, including but not limited to job-related knowledge/skills, experience, and geographic location. Compensation decisions are dependent upon the facts and circumstances of each position and candidate. In addition to base pay, we offer competitive bonus and benefits, including medical, dental, and vision coverage, 401(k), tuition reimbursement, medical leave programs, parental leave, generous PTO, paid company holidays, 8 hours of volunteer time annually, and a variety of wellness offerings such as EAP.
  • Inclusion + Belonging: Committed to Welcoming, Celebrating and Thriving. Learn more about our Employee Inclusion Groups on our website https://www.smith-nephew.com/
  • Your Future: 401k Matching Program, 401k Plus Program, Discounted Stock Options, Tuition Reimbursement
  • Work/Life Balance: Flexible Personal/Vacation Time Off, Paid Holidays, Flex Holidays, Paid Community Service Day
  • Your Wellbeing: Medical, Dental, Vision, Health Savings Account (Employer Contribution of $500+ annually), Employee Assistance Program, Parental Leave, Fertility and Adoption Assistance Program
  • Flexibility: Hybrid Work Model (For most professional roles)
  • Training: Hands-On, Team-Customized, Mentorship
  • Extra Perks: Discounts on fitness clubs, travel and more!

Smith+Nephew provides equal employment opportunities to applicants and employees without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability.
Stay connected by joining our Talent Community.
We're more than just a company - we're a community! Follow us on LinkedIn to see how we support and empower our employees and patients every day.
Check us out on Glassdoor for a glimpse behind the scenes and a sneak peek into You. Unlimited., life, culture, and benefits at S+N.
Explore our website and learn more about our mission, our team, and the opportunities we offer.

What Smith & Nephew employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

Apply