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Director Clinical Optimization Jobs (NOW HIRING)

Avalyn Pharma

Director, Clinical Development

OR · On-site +1

The company is advancing optimized inhaled formulations of established antifibrotic medicines ... The Director, Clinical Development will report to the Senior Vice President, Clinical Development ...

Avalyn Pharma

Director, Clinical Development

The company is advancing optimized inhaled formulations of established antifibrotic medicines ... The Director, Clinical Development will report to the Senior Vice President, Clinical Development ...

BioAge

$59K - $80K/yr

Reporting to the Senior Director, Clinical Science, the Director of Clinical Science provides ... selection, optimization and justification (FIH starting dose through registrational dose)

The Aspen Group

This Director is part of a team that drives clinical excellence, value creation, growth, and optimization. Success in the role will require excellent listening, planning, assessment and communication ...

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Director Clinical Optimization information

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$51.5K

$100.1K

$167K

How much do director clinical optimization jobs pay per year?

As of Sep 11, 2026, the average yearly pay for director clinical optimization in the United States is $100,124.00, according to ZipRecruiter salary data. Most workers in this role earn between $80,000.00 and $109,000.00 per year, depending on experience, location, and employer.

What does a director of clinical optimization do?

A Director of Clinical Optimization is responsible for improving healthcare processes, workflows, and outcomes by leveraging data, technology, and best practices. They work closely with clinical staff and leadership to identify areas for improvement, implement evidence-based solutions, and monitor results. Their goal is to enhance patient care quality, increase operational efficiency, and support organizational objectives through continuous process optimization.

What are the key skills and qualifications needed to thrive as a director of clinical optimization?

To thrive as a Director of Clinical Optimization, you need expertise in clinical operations, healthcare analytics, process improvement, and a relevant clinical or healthcare administration degree. Familiarity with electronic health record (EHR) systems, data analytics platforms, and certifications such as Lean Six Sigma are typically required. Strong leadership, strategic thinking, and excellent communication skills help drive change and foster collaboration across multidisciplinary teams. These skills are crucial for enhancing clinical workflows, improving patient outcomes, and achieving organizational efficiency in a dynamic healthcare environment.

How does a director of clinical optimization typically collaborate with clinical and administrative teams to implement process improvements?

A Director of Clinical Optimization works closely with both clinical staff and administrative leaders to identify inefficiencies in workflows and develop strategies for improvement. This often involves leading interdisciplinary meetings, analyzing data on patient outcomes and resource utilization, and facilitating change management initiatives. Effective communication and teamwork are essential, as the Director must bridge the gap between clinical needs and operational goals, ensuring that process changes are both patient-centered and aligned with organizational objectives. Regular collaboration with IT, quality assurance, and frontline caregivers is also key to successful implementation.

What is the difference between Director Clinical Optimization vs Clinical Operations Manager?

AspectDirector Clinical OptimizationClinical Operations Manager
CredentialsTypically requires advanced degrees (e.g., Master’s or PhD), certifications in clinical research or healthcare managementBachelor’s or Master’s degree in healthcare, life sciences, or related field; certifications may vary
Work EnvironmentStrategic planning, process improvement, cross-department collaborationOversees daily clinical operations, manages staff, ensures compliance
Employer & Industry UsageUsed in pharmaceutical, biotech, and healthcare organizations focusing on clinical process optimizationCommon in hospitals, clinics, and research institutions managing clinical workflows

The Director Clinical Optimization focuses on improving clinical processes and strategic initiatives, while the Clinical Operations Manager handles daily clinical activities and staff management. Both roles are vital but differ in scope and responsibilities.

What are popular job titles related to Director Clinical Optimization jobs?

For Director Clinical Optimization jobs, the most frequently searched job titles are:

Infographic showing various Director Clinical Optimization job openings in the United States as of September 2026, with employment types broken down into 3% As Needed, 74% Full Time, 15% Part Time, and 8% Contract. Highlights an 85% Physical, 1% Hybrid, and 14% Remote job distribution, with an average salary of $100,124 per year, or $48.1 per hour.

Director - Clinical Optimization and Efficiency

Atlanta, GA • On-site

Piedmont Healthcare Inc.
Health Care and Social Assistance • 10K+ employees
Learn more about Piedmont Healthcare Inc.external

$75K - $103K/yr

Full-time

Re-posted 24 days ago

Piedmont Healthcare rating

7.1

Company rating: 7.1 out of 10

Based on 469 frontline employees who took The Breakroom Quiz

Job description

The System Director of Clinical Practice Optimization and Efficiency will provide strategic and clinical leadership to advance enterprise-wide initiatives that enhance the quality, safety, and efficiency of oncology care delivery. This role is accountable for designing, standardizing, documenting and optimizing clinical workflows for Piedmont Oncology employed practices, hospital-based oncology departments and care team members to ensure evidence-based practice, operational excellence, and seamless integration. Key responsibilities include oversight of clinical protocols, oncology nurse navigation, clinical care pathways, quality improvement initiatives, and alignment of clinical operations with regulatory standards and accreditation requirements. The role has direct management of the centralized Piedmont Oncology Navigation Center's clinical staff, cancer genetics, and Lead Advanced Practice Providers. The System Director will lead efforts to reduce unwarranted variation, improve throughput, and support resource stewardship while fostering a culture of continuous improvement. This position collaborates closely with the Director of Infusion and Radiation Business Operations and hospital-based Directors of Oncology Operations to execute system-wide initiatives that support growth, sustainability, and exceptional clinical care.
Education
  • Graduate from a recognized, accredited school of nursing with current Georgia license for Advanced Practice Nursing and a Masters degree in Nursing Required or

  • Graduate of an accredited accredited Physician Assistants program with current license for the Georgia State Composite Board. Required

  • Clinical doctoral degree (e.g. Doctor of Nursing Practice) Preferred
Work Experience
  • 10 years of progressively responsible oncology experience to include five (5) years of leadership experience managing clinical operations for oncology service lines. Required

  • Experience practicing as an advanced practice provider in oncology Preferred
Licenses and Certifications
  • Licensed for Advanced Practice Nursing (ACNP/FNP) Upon Hire Required or

  • PA - Physician Assistant Licensed Physician Assistant in the State of Georgia Upon Hire Required and

  • Updated NCCPA certification for PAs Upon Hire Required

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