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Mountain View Rehabilitation and Senior Living Center

$60 - $80/hr

Clinical Business Development Liaison Location: Northumberland County, PA Company: Mountain View Rehabilitation and Senior Living Center Company Description: At Mountain View Rehabilitation and ...

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Business Development Director

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$125 - $150/hr

Position Summary The Business Development Director plays a pivotal role in driving the growth and ... Clinical Liaison Management: * Oversee the activities of Clinical Liaisons, providing direction ...

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Director, Business Development

$100K - $135K/yr

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As of Sep 9, 2026, the average yearly pay for director clinical business development in the United States is $126,639.00, according to ZipRecruiter salary data. Most workers in this role earn between $93,500.00 and $151,500.00 per year, depending on experience, location, and employer.

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Infographic showing various Director Clinical Business Development job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 83% Full Time, 14% Part Time, and 2% Contract. Highlights an 86% Physical, 3% Hybrid, and 11% Remote job distribution, with an average salary of $126,639 per year, or $60.9 per hour.

Director, Clinical Business Operations

South San Francisco, CA • On-site

Maze Therapeutics
Biotechnology Research and Development • 11 - 50 employees
Learn more about Maze Therapeuticsexternal

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 6 days ago

Job description

The Position
At Maze Therapeutics, we believe precision medicine has the power to transform the lives of patients with both common and rare diseases. As Director, Clinical Business Operations, you will serve as a strategic business partner to the Head of Clinical Operations and the Clinical Development organization. Working closely with Finance and cross-functional stakeholders, you will provide direction for the financial planning, budgeting, contracting, and operational business processes that support efficient and predictable clinical trial execution.
In partnership with the Head of Clinical Operations, Oversight Directors, Study Leads, and Clinical Development functional leaders, you will oversee study and program budgets, financial forecasting, vendor financial management, and clinical business operations across the development portfolio. You will help build scalable processes, establish budgeting standards, and provide the financial insights needed to support informed business decisions while maintaining sound fiscal stewardship.
This role requires a highly collaborative professional who enjoys solving complex operational challenges and working across Clinical Operations, Safety, Biometrics, Finance, Procurement, Legal, and external partners to support operational effectiveness and organizational success.
The Impact You'll Have
  • Clinical Business Operations Leadership
    • Serve as a strategic business partner to the Head of Clinical Operations, providing financial and operational guidance to the Clinical Development organization.
    • Develop scalable business processes, governance models, and operational standards that improve forecasting accuracy, budget visibility, and operational quality and decision-making.
    • Oversee Clinical Development's preferred vendor program by evaluating emerging vendors, establishing strategic partnerships, and maintaining a strong network of qualified providers that support current and future development programs.
    • Establish standardized budgeting methodologies, templates, assumptions, and financial tools aligned with industry benchmarks and organizational needs.
    • Develop dashboards and KPIs that provide visibility into budget performance, vendor spend, forecasting accuracy, contracting timelines, and operational efficiency.
  • Budget Strategy & Financial Management:
    • Oversee development of study budgets from protocol planning through study closeout, ensuring budgets appropriately reflect study objectives and operational requirements.
    • Partner with Clinical Study Leads and Oversight Directors and Clinical Development Functional Leads to develop realistic financial forecasts and proactively manage study financial risks.
    • Collaborate closely with Finance to support monthly accruals and forecasting, quarterly financial updates, annual operating plans, and long-range portfolio planning.
    • Monitor study financial performance, identify budget variances, and develop mitigation strategies to maintain financial objectives.
    • Prepare executive-level financial analyses, dashboards, and budget reporting to support portfolio and corporate decision-making.
    • Ensure vendors maintain accurate change logs and communicate budget impacts in a timely and transparent manner where applicable.
  • Contract & Budget Negotiations
    • Facilitate negotiations for CRO, vendor, and clinical site budgets, balancing market competitiveness, operational requirements, study timelines, and organizational financial objectives.
    • Partner with Legal to support negotiation and execution of Master Service Agreements (MSAs), work orders, study budgets, site budgets, change orders, and other clinical service agreements.
    • Develop negotiation strategies, templates, and playbooks that establish organizational standards and improve consistency across studies.
    • Serve as the Clinical Operations subject matter expert for financial negotiations, providing strategic guidance to Study Leads, Oversight Directors, and senior leadership.
    • Maintain awareness of industry pricing trends and fair market value benchmarks to support competitive and fiscally responsible negotiations.
    • Serve as the senior operational escalation point for CRO, vendor, and critical site performance issues
  • Vendor Financial Management
    • Develop and oversee financial governance for CROs, vendors, and central laboratories, ensuring budget adherence, accurate forecasting, and contractual compliance for Clinical Development vendors.
    • Build collaborative relationships with strategic vendors that promote financial transparency, accountability, and high-quality execution.
    • Partner with vendors to proactively identify financial risks and develop mitigation strategies before they impact study execution.
    • Establish vendor performance metrics related to financial delivery, forecasting accuracy, invoice quality, and budget management.
    • Support invoice review, financial reconciliation, and budget tracking throughout the lifecycle of each study.

Leadership Competencies
As a Director, we also expect our leaders to demonstrate the following Leadership Competencies:
  • Communication and Influence
    • Builds communication channels across Maze for sharing information
    • Influences Senior Management decisions through persuasive arguments
    • Respectfully addresses differing opinions leading to support of decision
  • Teamwork and Collaboration
    • Champions partnerships and connections across Maze
    • Proactively addresses issues that could result in breakdown of team relationships
    • Spotlights team and individual contributions in public forums
  • Execution and Results
    • Addresses gaps and leverages strengths to get best results
    • Maintains a steadying presence and clarifies priorities during change
    • Anticipates and removes barriers that put functional/corporate goals at risk
  • Develop Others and Self
    • Removes barriers to staff development and empowers them to make their own decisions
    • Stays current on industry trends and keeps direct-reports prepared and responsive
What We're Looking For
You might be the right fit for this role if you have:
  • Bachelor's degree in Business, Finance, Life Sciences, Healthcare Administration, or a related field.
  • 10-12+ years of experience in Clinical Business Operations, Clinical Finance, Strategic Sourcing, Clinical Operations, or related business roles within biotechnology, pharmaceutical, or CRO organizations.
  • Extensive experience developing and managing global clinical trial budgets across all phases of clinical development.
  • Demonstrated success negotiating CRO, vendor, and investigator site budgets, including Master Service Agreements, work orders, study budgets, site budgets, and change orders.
  • Strong understanding of clinical development, outsourcing models, fair market value methodologies, vendor contracting, and financial planning processes.
  • Experience partnering closely with Finance on monthly accruals and forecasting, annual budgeting, long-range planning, and financial governance.
  • Strong financial acumen with demonstrated ability to analyze complex financial data and translate insights into strategic business recommendations.
  • Experience establishing scalable business processes, templates, governance models, and operational standards within a growing organization.
  • Exceptional negotiation, project management, organizational, and problem-solving skills.
  • Outstanding communication and interpersonal skills with the ability to influence cross-functional teams, external partners, and executive leadership.
  • Ability to thrive in a fast-paced, evolving biotech environment while managing multiple priorities with a strong sense of urgency.
  • Willing to occasionally travel to support vendor relationship needs.
About Maze Therapeutics
Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases. Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1-mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease.
Our People
Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.
Our Core Values
Further Together - Our path is paved with challenges, but with resilience and a team-first mentality, we'll achieve our mission.
Impact Obsessed - We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.
Stand True - Our integrity is foundational; it guides us no matter the obstacle.
The expected annual salary range for employees located in the San Francisco Bay Area is $222,000 - $271,000. Additionally, this position is eligible for an annual performance bonus.
Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future.
Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.
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