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Director Analytical Development Jobs in Boston, MA

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Director Analytical Development information

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$96.7K

$207.9K

$312.3K

How much do director analytical development jobs pay per year?

As of Aug 31, 2026, the average yearly pay for director analytical development in Boston, MA is $207,950.00, according to ZipRecruiter salary data. Most workers in this role earn between $102,100.00 and $270,500.00 per year, depending on experience, location, and employer.

What is a director analytical development?

A Director of Analytical Development oversees the strategy, development, and implementation of analytical methods to support product development and manufacturing. They lead a team of scientists, ensure regulatory compliance, and collaborate with cross-functional teams to optimize processes. Their role includes troubleshooting analytical issues, validating methods, and contributing to regulatory submissions. This position is critical in maintaining product quality and ensuring data-driven decision-making in pharmaceutical, biotechnology, or related industries.

What are the typical daily responsibilities of a director analytical development?

A Director Analytical Development typically oversees the design, implementation, and optimization of analytical methods to support product development and quality control. This involves leading a team of scientists, ensuring projects meet regulatory requirements, troubleshooting technical challenges, and collaborating closely with cross-functional groups such as R&D, quality assurance, and manufacturing. Daily tasks often include reviewing analytical data and reports, planning project timelines, and making strategic decisions to align with organizational objectives. The role requires balancing hands-on scientific guidance with high-level management to drive innovation and efficiency within the analytical function.

What are the key skills and qualifications needed to thrive in the director analytical development position, and why are they important?

To thrive as a Director Analytical Development, you generally need an advanced degree in chemistry, biochemistry, or a related scientific field, along with substantial experience in analytical method development and validation, and team leadership. Familiarity with laboratory information management systems (LIMS), chromatographic and spectroscopic instrumentation, and regulatory guidelines such as ICH, FDA, and GMP is crucial. Excellent project management, strategic thinking, and interpersonal communication are standout soft skills for this position. These competencies enable effective oversight of complex analytical projects, ensure regulatory compliance, and foster team collaboration in a fast-paced R&D environment.

What are the most commonly searched types of Analytical Development jobs in Boston, MA?

The most popular types of Analytical Development jobs in Boston, MA are:

What are popular job titles related to Director Analytical Development jobs in Boston, MA?

For Director Analytical Development jobs in Boston, MA, the most frequently searched job titles are:

What job categories do people searching Director Analytical Development jobs in Boston, MA look for?

The top searched job categories for Director Analytical Development jobs in Boston, MA are:

What cities near Boston, MA are hiring for Director Analytical Development jobs?

Cities near Boston, MA with the most Director Analytical Development job openings:

Director Analytical Development jobs near you
Infographic showing various Director Analytical Development job openings in Boston, MA as of August 2026, with employment types broken down into 1% As Needed, 82% Full Time, 14% Part Time, and 3% Contract. Highlights an 90% Physical, 3% Hybrid, and 7% Remote job distribution, with an average salary of $207,950 per year, or $100 per hour.

Director, Analytical Development

Lexington, MA • On-site, Remote

Keros Therapeutics
Biotechnology Research and Development • 1 - 10 employees
Learn more about Keros Therapeuticsexternal

Full-time

Re-posted 9 days ago

Job description

At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients.
Job Summary
Keros Therapeutics is seeking an expert in Analytical Science and Protein Characterization to join our team as Director of Analytical Development. The incumbent will lead the analytical strategy, method development, and characterization for our novel protein pipeline. The ideal candidate will have a deep understanding of protein characterization hands-on experience in the laboratory, excellent organizational skills and attention to detail, a demonstrated ability for self-motivated and independent project execution, and a strong desire to learn. This position requires deep expertise in modern analytical chemistry and a strong ability to translate complex data into actionable scientific decisions. The ideal candidate will combine technical depth with proven leadership experience, sound scientific judgment, and the ability to build productive partnerships across internal teams and external collaborators.
Primary Responsibilities
  • Lead analytical development strategy for early to late-stage biologics programs, including Pre-Clinical, Phase I and Phase II/III
  • Develop the strategic implementation of increasing levels of structural, physical, and advanced protein characterization in phase appropriate manner
  • Serve as the subject-matter expert in protein characterization and stability for phase-appropriate development of the pipeline
  • Partner with Manufacturing, Process Development, and Quality teams to define and implement phase-appropriate analytical methods, specifications, and control strategies to support DS and DP
  • Advise and oversee CDMOs' analytical method development, transfer, and validation
  • Collaborate with CDMOs and CROs to develop and optimize a range of analytical assays for the release and characterization on a series of fusion protein and mAb biologics at each stage from preclinical to commercial launch
  • Provide oversight of CDMOs and external testing laboratories, ensuring timelines, data quality, and compliance
  • Ensure analytical methods and specifications are scientifically justified, phase appropriate, and compliant with applicable compendial standards and regulatory guidelines
  • Support comparability, stability, and characterization strategies for process changes and scale-up
  • Provide and develop laboratory based analytical support to upstream and downstream process development to drive new and improved processes for DS production
  • Provide leadership and mentorship to a team of scientists and analysts
  • Support cross-functional team coordinating efforts of the Technical Operations, Quality, and Regulatory to advance programs
  • Drive analytical support for regulatory submissions, including IND amendments, BLA/MAA filings, and responses to health authority questions
  • Author Analytical CMC sections of IND filings, internal SOPs, experimental procedures, training and safety documents

Core Competencies (Required Skills)
  • Experience with biologics analytical support in late-stage activities (Phase 3 and commercialization)
  • Strong background in protein characterization, analytical method development, qualification/validation, and physicochemical characterization of fusion proteins and protein therapeutics
  • Deep understanding of analytical methods and data interpretation to evaluate protein structure, post translational modifications, and characterization
  • Experience supporting transitions from discovery through IND-enabling or early clinical development is strongly valued

Education Requirements and Qualifications
  • MS with 10+ years or PhD with 7+ years in molecular/cellular/structural biology, biochemistry, or a related field
  • Proficiency with biochemical and biophysical methods:
    • CE (CSDS, CIEF and CGE DNA), qPCR, potency, MFI/HIAC, DSF, DLS, DSC, and LCMS/MS peptide mapping & subunit analysis
    • Chromatography: IA, SEC, RP, HIC and IEX
    • Glycosylation: monosaccharide, sialic acid characterization and N-linked Glycan analysis
    • Spectroscopy: UV/Vis, luminescence
  • Experience in biochemistry techniques such as protein expression, gel electrophoresis, protein quantification assays, ELISA, cell-based assays, and enzyme kinetics
  • Understanding of molecular biology, recombinant protein expression and construct design for affinity purification methods; familiarity with standard expression hosts such as mammalian, is a plus
  • Experience in purifying proteins through recombinant processes is a plus
  • Excellent collaboration skills and ability to work cross functionally to achieve objectives
  • Strong work ethic, motivation, and scientific curiosity

This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, and other relevant factors.
Potential base pay range
$200,000-$226,000 USD
Our Diversity, Equity & Inclusion Mission Statement:Keros is an inclusive company. We believe that diversity drives innovation. We continue to build an inclusive culture that encourages, supports, and celebrates the diverse voices of our employees. As such, Keros takes a holistic approach in mentoring, coaching, and developing all of our Keros team members.
Keros Therapeutics is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law.
Recruitment & Staffing Agencies:Keros Therapeutics does not accept unsolicited resumes from any source other than the candidate directly. Any unsolicited submission by an agency to Keros is prohibited. Any resume submitted by an agency without a signed contract or expressed consent by a member of the Keros Therapeutics Human Resources Department, will be considered property of Keros Therapeutics, and no fee shall be owed with respect thereto.

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