Author and execute the regional data engagement strategy, guiding how field scientists partner with oncologists, pathologists, and biometricians to unlock complex ctDNA and real-world datasets; holds ...
Technical fluency in ctDNA, NGS technologies, and assay performance tradeoffs * Knowledge of U.S. diagnostic reimbursement and access pathways * Strong analytical, financial modeling, and ...
Technical fluency in ctDNA, NGS technologies, and assay performance tradeoffs * Knowledge of U.S. diagnostic reimbursement and access pathways * Strong analytical, financial modeling, and ...
Technical fluency in ctDNA, NGS technologies, and assay performance tradeoffs * Knowledge of U.S. diagnostic reimbursement and access pathways * Strong analytical, financial modeling, and ...
Technical fluency in ctDNA, NGS technologies, and assay performance tradeoffs * Knowledge of U.S. diagnostic reimbursement and access pathways * Strong analytical, financial modeling, and ...
Director Translational Research (On site)
$220K - $247K/yr
Clinical biomarker strategies include tissue and blood-based assays, e.g., LC-MS, IHC/IF, ctDNA, NGS, and other potential biomarker readouts. * Lead translational research strategy from discovery ...
Director Translational Research (On site)
$220K - $247K/yr
Clinical biomarker strategies include tissue and blood-based assays, e.g., LC-MS, IHC/IF, ctDNA, NGS, and other potential biomarker readouts. * Lead translational research strategy from discovery ...
While MRD will be the initial anchor, this will evolve alongside the precision oncology diagnostic portfolio to include broader solid tumor biomarkers, ctDNA and liquid biopsy applications, and ...
While MRD will be the initial anchor, this will evolve alongside the precision oncology diagnostic portfolio to include broader solid tumor biomarkers, ctDNA and liquid biopsy applications, and ...
Director, Immuno-oncology Bioinformatics
Waltham, MA · On-site
$181K - $272K/yr
Integrate diverse data types - RNAseq, TCRseq, ctDNA, cytokines, spatial transcriptomics - into robust biological insights. 4. Apply Advanced Computational Approaches: Leverage AstraZeneca's rich ...
Director, Immuno-oncology Bioinformatics
Waltham, MA · On-site
$181K - $272K/yr
Integrate diverse data types - RNAseq, TCRseq, ctDNA, cytokines, spatial transcriptomics - into robust biological insights. 4. Apply Advanced Computational Approaches: Leverage AstraZeneca's rich ...
Director, Immuno-oncology Bioinformatics
Waltham, MA · On-site
$181K - $272K/yr
Integrate diverse data types - RNAseq, TCRseq, ctDNA, cytokines, spatial transcriptomics - into robust biological insights. 4. Apply Advanced Computational Approaches: Leverage AstraZeneca's rich ...
Director, Immuno-oncology Bioinformatics
Waltham, MA · On-site
$181K - $272K/yr
Integrate diverse data types - RNAseq, TCRseq, ctDNA, cytokines, spatial transcriptomics - into robust biological insights. 4. Apply Advanced Computational Approaches: Leverage AstraZeneca's rich ...
Sr. Bioinformatics Scientist - DNA Technology Development & Applied AI
Fremont, CA · On-site
$155K - $190K/yr
This position will directly contribute to a new generation of genomics-based precision-medicine products for profiling MRD, ctDNA dynamics, and patient response to treatment. Our products are used by ...
Sr. Bioinformatics Scientist - DNA Technology Development & Applied AI
Fremont, CA · On-site
$155K - $190K/yr
This position will directly contribute to a new generation of genomics-based precision-medicine products for profiling MRD, ctDNA dynamics, and patient response to treatment. Our products are used by ...
Proven experience leading development of oncology diagnostics, preferably tumor tissue sequencing assays and/or ctDNA based assays for somatic mutation detection * Experience with tumor tissue sample ...
Proven experience leading development of oncology diagnostics, preferably tumor tissue sequencing assays and/or ctDNA based assays for somatic mutation detection * Experience with tumor tissue sample ...
Familiarity with a broad range of biomarker assays (NGS of ctDNA and tumor tissues). * Prior experience building or scaling clinical biomarker operations functions in a rapidly growing organization ...
Familiarity with a broad range of biomarker assays (NGS of ctDNA and tumor tissues). * Prior experience building or scaling clinical biomarker operations functions in a rapidly growing organization ...
Technical fluency in ctDNA, NGS technologies, and assay performance tradeoffs * Knowledge of U.S. diagnostic reimbursement and access pathways * Strong analytical, financial modeling, and ...
Technical fluency in ctDNA, NGS technologies, and assay performance tradeoffs * Knowledge of U.S. diagnostic reimbursement and access pathways * Strong analytical, financial modeling, and ...
Proven experience leading development of oncology diagnostics, preferably tumor tissue sequencing assays and/or ctDNA based assays for somatic mutation detection * Experience with tumor tissue sample ...
Proven experience leading development of oncology diagnostics, preferably tumor tissue sequencing assays and/or ctDNA based assays for somatic mutation detection * Experience with tumor tissue sample ...
Proven experience leading development of oncology diagnostics, preferably tumor tissue sequencing assays and/or ctDNA based assays for somatic mutation detection * Experience with tumor tissue sample ...
Quick apply
Proven experience leading development of oncology diagnostics, preferably tumor tissue sequencing assays and/or ctDNA based assays for somatic mutation detection * Experience with tumor tissue sample ...
Director, Immuno-oncology Bioinformatics
Waltham, MA · On-site
$181K - $272K/yr
Integrate diverse data types - RNAseq, TCRseq, ctDNA, cytokines, spatial transcriptomics - into robust biological insights. 4. Apply Advanced Computational Approaches: Leverage AstraZeneca's rich ...
Director, Immuno-oncology Bioinformatics
Waltham, MA · On-site
$181K - $272K/yr
Integrate diverse data types - RNAseq, TCRseq, ctDNA, cytokines, spatial transcriptomics - into robust biological insights. 4. Apply Advanced Computational Approaches: Leverage AstraZeneca's rich ...
Medical Director, Genitourinary (GU) Oncology
Chicago, IL · On-site
$250 - $350/hr
Clinical Development: * Collaborate with the Chief Medical Officer and other Medical Directors in Oncology on the clinical development of ctDNA-based diagnostics. * Lead development and ...
Medical Director, Genitourinary (GU) Oncology
Chicago, IL · On-site
$250 - $350/hr
Clinical Development: * Collaborate with the Chief Medical Officer and other Medical Directors in Oncology on the clinical development of ctDNA-based diagnostics. * Lead development and ...
Translational Biomarker Analysis with multi-modality and multi-omics assays such as Bulk and Single cell RNA-seq, TCR/BCR-seq, WGS/WES, Amplicon-seq, ATAC-seq, ctDNA/liquid biopsy, Proteomics and ...
Translational Biomarker Analysis with multi-modality and multi-omics assays such as Bulk and Single cell RNA-seq, TCR/BCR-seq, WGS/WES, Amplicon-seq, ATAC-seq, ctDNA/liquid biopsy, Proteomics and ...
Scientist/Sr. Scientist - NGS
Waltham, MA · On-site
Experience working with liquid biopsy samples (cfDNA/ctDNA, cfRNA, or exosomes). * Familiarity with NGS QC metrics and analysis tools. * Understanding of assay validation in regulated environments ...
Scientist/Sr. Scientist - NGS
Waltham, MA · On-site
Experience working with liquid biopsy samples (cfDNA/ctDNA, cfRNA, or exosomes). * Familiarity with NGS QC metrics and analysis tools. * Understanding of assay validation in regulated environments ...
This is a high-impact, tumor-specific role focused on accelerating the adoption and growth of Signatera-our groundbreaking, first-in-class MRD ctDNA test. As a COS, you'll act as a strategic field ...
This is a high-impact, tumor-specific role focused on accelerating the adoption and growth of Signatera-our groundbreaking, first-in-class MRD ctDNA test. As a COS, you'll act as a strategic field ...
This is a high-impact, tumor-specific role focused on accelerating the adoption and growth of Signatera-our groundbreaking, first-in-class MRD ctDNA test. As a COS, you'll act as a strategic field ...
This is a high-impact, tumor-specific role focused on accelerating the adoption and growth of Signatera-our groundbreaking, first-in-class MRD ctDNA test. As a COS, you'll act as a strategic field ...
Technical familiarity with DNA sequencing, RNA sequencing, methylation, and ctDNA assays * Hands-on experience with digital pathology software and whole-slide imaging analysis * Exposure to survival ...
Ctdna information
What are the applications of ctDNA?
What is it called when you work with DNA?
What is the difference between Ctdna vs ctDNA?
| Aspect | Ctdna | ctDNA |
|---|---|---|
| Definition | Circulating tumor DNA (Ctdna) refers to tumor-derived DNA fragments found in the bloodstream. | Circulating tumor DNA (ctDNA) is the same as Ctdna, representing tumor DNA fragments in blood. |
| Usage | Used in cancer detection, monitoring treatment response, and minimal residual disease. | Used similarly for cancer detection, prognosis, and treatment monitoring. |
| Work Environment | Laboratories performing liquid biopsies and molecular diagnostics. | Same as Ctdna, in clinical labs and research settings. |
| Certifications | Requires molecular biology, genetics, or pathology certifications. | Same certifications as Ctdna, often overlapping. |
Both Ctdna and ctDNA refer to tumor-derived DNA fragments circulating in the blood, used interchangeably in clinical and research settings for cancer diagnostics and monitoring.
What are the top liquid biopsy companies?
What does ctDNA do?

Natera rating
7.6
Based on 37 frontline employees who took The Breakroom Quiz
54th of 105 rated laboratories
Job description
Natera is shifting disease management worldwide through unprecedented molecular innovation. As the Director of Field Translational Science, you will build, scale, and lead a specialized team of field-facing translational scientists within our Oncology Business Unit. This high-autonomy leadership role is designed for a strategic builder who can run a sophisticated regional team while serving as the executive authority for advanced Natera tests - including, but not limited to, cell-free DNA (cfDNA) and minimal residual disease (MRD) assays - and their associated data analysis frameworks across elite academic medical centers.
This position requires up to 50-70% regional travel to engage with institutional leadership and audit high-priority research partnerships. You will eliminate the standard boundaries between field data generation and internal pipeline design. Distinct from traditional, education-focused Medical Affairs teams (MSLs), your organization owns the structural integrity, statistical validation, and scientific output of investigator-led data collaborations.
Primary Responsibilities- Team Leadership & Scale: Hire, develop, and manage a premier field organization of translational scientists, establishing clear performance metrics tied to regional data velocity, scientific rigor, and publication quality.
- Strategic Data Architecture: Author and execute the regional data engagement strategy, guiding how field scientists partner with oncologists, pathologists, and biometricians to unlock complex ctDNA and real-world datasets; holds the institutional/enterprise escalation line for the direct day-to-day communication line with the clinicians.
- Regional Operations & Systems Governance: Oversee the secure regional tracking architecture and data ingestion pipelines that individual Field Translational Scientists operate within; ensure absolute data compliance, system integrity, and streamlined data flow from investigator sites into internal analysis platforms.
- Cross-Functional Governance: Command the interface between field operations and internal Oncology Translational Medicine & Scientific Communications, Medical Affairs, Life Cycle, R&D and Product Development leadership, translating field-derived real-world evidence into high-impact pipeline recommendations.
- Investigator-Led Portfolio Management: In partnership with MSLs, oversee the lifecycle of all regional investigator-initiated trials (IITs) and institutional registries, ensuring team members enable investigators to maximize the utility of Natera's proprietary analytical tools and data visualization platforms to achieve statistical robustness and prompt manuscript generation.
- Institutional Network Expansion: Secure, scale, and manage institutional data-sharing models, biobanking governance, and EMR data-integration initiatives with core comprehensive cancer networks.
- Scientific Advocacy & Compliance: Represent Natera as a senior scientific authority at major oncology congresses, ensuring all field data-handling methods maintain absolute alignment with HIPAA, CAP/CLIA, PHI data protocols, FDA regulations, and PhRMA codes of interaction.
- Required Education: PhD or MD in Cancer Biology, Genomics, Bioinformatics, or a related complex molecular science discipline.
- Required Experience: 6+ years of total experience within basic or translational oncology research, including a minimum of 2+ years of explicit people management experience leading high-performing scientific or clinical teams within the diagnostics, biotechnology or pharmaceutical sectors.
- Domain Mastery: Exceptional command of cancer biology and genetics, liquid biopsy modalities and clinical utilities, next-generation sequencing (NGS) and ctDNA workflows and data interpretation, and statistical methods.
- Data-Centric Track Record: Documented success managing complex genomic datasets, institutional electronic medical record (EMR) integrations, or complex clinical data registries.
- Leadership Style: Proven ability to manage teams through high ambiguity, prioritizing structured logic and rapid, high-judgment decision-making over consensus-driven delays.
- Operational Mobility: Ability and willingness to travel domestically up to 50-70% to support team execution, site audits, and principal investigator collaborations.