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Brookhaven National Laboratory

Cryo-EM Scientist

Upton, NY · On-site

$103K - $138K/yr

The national cryo-electron microscopy (cryo-EM) center, the Laboratory for BioMolecular Structure (LBMS) at Brookhaven National Laboratory, provides sample preparation, screening, and high-resolution ...

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How much do cryo em jobs pay per hour?

As of May 30, 2026, the average hourly pay for cryo em in the United States is $30.61, according to ZipRecruiter salary data. Most workers in this role earn between $13.94 and $28.61 per hour, depending on experience, location, and employer.

What is a Cryo-EM job?

A Cryo-EM job typically involves using cryo-electron microscopy (Cryo-EM) to study biological molecules at near-atomic resolution. Scientists in this field prepare biological samples, operate electron microscopes, and analyze 3D structures to understand molecular functions. These roles are common in academic research, pharmaceutical companies, and structural biology labs. Skills in sample preparation, data processing, and computational analysis are often required.

What are the key skills and qualifications needed to thrive in the Cryo Em position, and why are they important?

To thrive as a Cryo-EM (Cryogenic Electron Microscopy) Specialist, you need a strong background in structural biology, electron microscopy techniques, and data analysis, typically supported by an advanced degree in a relevant scientific field. Familiarity with high-end cryo-EM instruments, image processing software such as RELION or CryoSPARC, and proper certification or hands-on training are typically required. Exceptional attention to detail, problem-solving skills, and the ability to work collaboratively are essential soft skills that distinguish top candidates. These skills and qualifications are critical to ensuring high-quality data acquisition, accurate structural analysis, and effective teamwork in fast-paced research environments.

What are some typical responsibilities of a Cryo-EM Specialist during a project?

As a Cryo-EM Specialist, your typical responsibilities include preparing biological samples for imaging, operating cryogenic electron microscopes, and managing data acquisition sessions. You will also process and interpret large datasets using specialized software, troubleshoot instrument issues, and maintain detailed documentation of your experiments. Collaboration with researchers, lab staff, and multidisciplinary teams is common, as you provide expertise in experimental design and technical support. This role often involves staying current with advancements in technology and methods to ensure high-quality structural analysis.
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Cryo Em jobs near you
Infographic showing various Cryo Em job openings in the United States as of May 2026, with employment types broken down into 3% Locum Tenens, 83% Full Time, 12% Part Time, and 2% Contract. Highlights an 98% Physical, and 2% Remote job distribution, with an average salary of $63,678 per year, or $30.6 per hour.
Cryo-EM Scientist

Cryo-EM Scientist

Brookhaven National Laboratory

Upton, NY • On-site

$103K - $138K/yr

Full-time

Posted 3 days ago

Job description

The national cryo-electron microscopy (cryo-EM) center, the Laboratory for BioMolecular Structure (LBMS) at Brookhaven National Laboratory, provides sample preparation, screening, and high-resolution data collection for both single-particle cryo-EM and cryo-electron tomography (cryo-ET) studies.
The facility currently hosts one high-end Krios microscope, one Talos 120C and one JEM 2100 screening electron microscopes, an Aquilos2 cryo-focused-ion beam scanning electron microscope (cryo-FIB-SEM), an EM ICE high-pressure freezer, and cryo-grids preparation equipment.
Position Description
The LBMS is seeking an experienced scientist to join our team and support our efforts in operation and improvement of LBMS cryo-EM capabilities. The cryo-EM scientist will help users obtain high-quality Cryo-EM data, lead cryo-EM efforts on collaboration projects, participate in LBMS 3-tier training program, and develop/implement new methods.
The successful candidate will have a strong background in biology, and experience with cryo-EM techniques.
Essential Duties and Responsibilities:
  • Operate and maintain cryo-EMs and related equipment, including sample preparation and image acquisition.
  • Train, support and educate users and the public through the 3-tier training program.
  • Collaborate with users to design and optimize experiments; provide guidance on sample preparation, data collection, and analysis.
  • Communicate with academic and industrial user communities and provide support.
  • Contribute to method development in cryo-EM and support overall LBMS operations.

Required Knowledge, Skills, and Abilities:
  • PhD in a relevant field (e.g., biology, biochemistry, biophysics, chemistry, microbiology, virology) with ≥2 years postdoctoral experience.
  • Effective and constructive communicator.
  • Ability to work both independently as a self-starter and as a proactive team player.
  • Ability to maintain a flexible schedule, including evenings and weekends, to support continuous facility operations and user needs.
  • Strong organizational and record-keeping skills.
  • Experience in at least one of the following: cryo-EM instrumentation, sample preparation, high-resolution single particle data collection, or cryo-electron tomography.

Preferred Knowledge, Skills, and Experience in one or more of the following:
  • Single-particle image processing using CryoSPARC, Relion, cisTEM, EMAN2, or similar software.
  • Tomography image processing using IMOD, AreTomo, EMAN2, or related packages.
  • Cryogenic sample preparation using cryo-FIB or cryo-microtome.
  • Fluorescence light microscopy for correlative or complementary studies.
  • Experience in working in a Linux/UNIX environment.
  • Strong record of peer-reviewed publications.

Other Information:
  • Candidates should submit a CV/resume, a cover letter and contact information for three references.
  • Brookhaven Laboratory is committed to providing fair, equitable and competitive compensation. This is a multi-level role and the full salary range for this position is $103,000 - $138,000 / year. You will be placed at the level and salary commensurate with your experience. Salary offers will be commensurate with the final candidate's qualification, education and experience and considered with the internal peer group.

Brookhaven National Laboratory is committed to employee success and we believe that a comprehensive employee benefits program is an important and meaningful part of the compensation employees receive. Review more information at BNL | Benefits Program
Brookhaven National Laboratory requires all non-badged personnel including visitors to produce a REAL-ID or REAL-ID compliant documentation to access Brookhaven National Laboratory - view more information at www.bnl.gov/real-id. This is due to nationwide identification requirements for federal site access as required by the federal REAL ID Act. Those not in possession of a REAL ID-compliant document will not be permitted to access the site which includes access to the Laboratory for interviews.
About Us
Brookhaven National Laboratory (www.bnl.gov) delivers discovery science and transformative technology to power and secure the nation's future. Brookhaven Lab is a multidisciplinary laboratory with seven Nobel Prize-winning discoveries, 37 R&D 100 Awards, and more than 70 years of pioneering research. The Lab is primarily supported by the U.S. Department of Energy's (DOE) Office of Science. Brookhaven Science Associates (BSA) operates and manages the Laboratory for DOE. BSA is a partnership between Battelle and The Research Foundation for the State University of New York on behalf of Stony Brook University. BSA salutes our veterans and active military members with careers that leverage the skills and unique experience they gained while serving our country, learn more at BNL | Opportunities for Veterans at Brookhaven National Laboratory.
Equal Opportunity/Affirmative Action Employer
Guided by our core values of integrity, responsibility, innovation, respect, and teamwork, Brookhaven Science Associates is an Equal Employment Opportunity Employer-Vets/Disabled. We are committed to fostering a respectful and collaborative environment that fuels scientific discovery. We consider all qualified applicants without regard to any characteristic protected by law. All qualified individuals are encouraged to apply. We ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. *VEVRAA Federal Contractor
BSA employees are subject to restrictions related to participation in Foreign Government Talent Recruitment Programs, as defined and detailed in United States Department of Energy Order 486.1A. You will be asked to disclose any such participation at the time of hire for review by Brookhaven. The full text of the Order may be found at: https://www.directives.doe.gov/directives-documents/400-series/0486.1-BOrder-a/@@images/file

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