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Contract Senior Clinical Research Associate Jobs in Boca Raton, FL

ICON

Clinical Research Associate II

West Palm Beach, FL · On-site +1

Clinical Research Associate - Oncology - West Palm Beach, FL ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to ...

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Contract Senior Clinical Research Associate information

See Boca Raton, FL salary details

$34.2K

$89.5K

$136.2K

How much do contract senior clinical research associate jobs pay per year?

As of Aug 21, 2026, the average yearly pay for contract senior clinical research associate in Boca Raton, FL is $89,501.00, according to ZipRecruiter salary data. Most workers in this role earn between $59,300.00 and $121,500.00 per year, depending on experience, location, and employer.

What is a contract senior clinical research associate?

A Contract Senior Clinical Research Associate (CRA) is an experienced clinical research professional who works independently or through an agency on a contract basis, rather than as a permanent employee. Their primary role is to monitor clinical trials, ensuring that studies are conducted according to protocol, regulatory requirements, and Good Clinical Practice (GCP) guidelines. Senior CRAs have advanced knowledge of clinical trial processes and often oversee multiple sites or junior staff. They are responsible for reviewing data, managing documentation, and acting as a liaison between the study sponsor and the investigative sites. Contract positions offer flexibility and variety, but may require more travel and self-management.

What skills and qualifications are needed to thrive as a contract senior clinical research associate?

To thrive as a Contract Senior Clinical Research Associate, you need comprehensive knowledge of clinical trial processes, GCP/ICH guidelines, and relevant regulatory requirements, typically supported by a life sciences degree and several years of monitoring experience. Familiarity with Electronic Data Capture (EDC) systems, trial management software, and certifications like ACRP or SOCRA are commonly required. Exceptional organizational skills, attention to detail, and effective communication make someone stand out in this role. These skills and qualities are vital to ensure protocol compliance, high data quality, and successful collaboration across study sites.

How does a contract senior clinical research associate typically collaborate with study sites and sponsors during a clinical trial?

As a Contract Senior Clinical Research Associate (CRA), you play a key liaison role between study sites and sponsors. You are responsible for monitoring site performance, ensuring protocol compliance, and addressing any issues that arise during the trial. Regular communication with site staff and sponsor representatives is essential, often involving site visits, remote monitoring, and reporting. Effective collaboration helps maintain study integrity, ensures regulatory requirements are met, and facilitates the timely progression of the clinical trial.

What is the difference between Contract Senior Clinical Research Associate vs Clinical Research Associate?

AspectContract Senior Clinical Research AssociateClinical Research Associate
CredentialsBachelor's degree, relevant certifications, experience in clinical trialsBachelor's degree, entry-level certifications often sufficient
Work EnvironmentContract basis, often in multiple sites or projects, possibly remoteFull-time or part-time, typically at a single site or sponsor location
Employer & Industry UsagePharmaceutical companies, CROs, biotech firms, project-basedPharmaceutical companies, CROs, hospitals, research sites

The Contract Senior Clinical Research Associate typically has more experience, handles complex trial aspects, and works on a contractual basis. The Clinical Research Associate is often an entry-level or mid-level role focused on site monitoring and data collection. Both roles are essential in clinical trials but differ mainly in experience level and employment type.

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For Contract Senior Clinical Research Associate jobs in Boca Raton, FL, the most frequently searched job titles are:

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The top searched job categories for Contract Senior Clinical Research Associate jobs in Boca Raton, FL are:

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Contract Senior Clinical Research Associate jobs near you
Infographic showing various Contract Senior Clinical Research Associate job openings in Boca Raton, FL as of August 2026, with employment types broken down into 2% As Needed, 72% Full Time, 20% Part Time, and 6% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $89,501 per year, or $43 per hour.

Senior Clinical Research Associate

Icon plc

Fort Lauderdale, FL • Hybrid

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 14 days ago

Job description

Senior Clinical Research Associate - Oncology Phase I - Miami, FL

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.


As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.


The Sr. Clinical Research Associate (Sr. CRA) willbe responsible forperforming investigative site management and monitoring activities throughout the clinical trial lifecycle. This Sr. CRA role will support the client's Oncology clinical trials to ensure data integrity, subject safety, andinspectionreadiness at the clinical investigative sites.

Responsibilities:

  • Perform site management activities to support the client's Oncology site successandmaintainacontinuous state of inspection readiness

  • Act as the primary contactandfacilitateefficientcommunications between the client's clinical trial team and the sites

  • Perform remote and on-sitemonitoring/co-monitoringvisits (Site Qualification Visits, Site Initiation Visits, Interim Monitoring Visits and Close-Out Visits) to ensure data integrity and subject safety in the client's trials

  • May perform oversight activities to assess monitoring quality and train/mentor less experienced CRAs

  • Promptly document monitoring activitiesandsubmit/approvevisit reports

  • Manage site essential document collection and TMF reconciliation with site files

  • Support sites with local Institutional Review Board (IRB)/Ethics Committee (EC) submissions and confirm approvals

  • Regularly review site Key Risk Indicator (KRI)metrics,issuesandaction items to detect trends and ensure prompt resolution

  • Independentlydeterminerootcauses and develop/implement site Corrective Action and Preventive Action (CAPA) plans

  • Deliver training to ensure sitescomply withthe protocol, Standard Operating Procedures (SOPs), Good Clinical Practices (GCPs)and regulations

  • Support sites and the client's regulatory inspections

  • Contribute to site identification; drive site feasibility and qualification progress; and support site activationactivities

  • Lead site engagement initiatives and foster relationships with key Oncology sites and networks

Qualifications

  • Bachelor's degree (scientific field preferred)

  • 5+yearsmonitoringclinicaltrials independently conducting on-site and remote monitoring visits. Atleast 2 years monitoring solid tumor clinical trials.

  • 1+ years early development trialexperience

  • Solidtumorclinicaltrial experience is required

  • Experience utilizing Veeva systems is highly preferred

  • Demonstrated experiencedeveloping/maintainingsiterelationships and securing compliance

  • ExpertiseinGxPsandOncology monitoring techniques (including Risk-Based Monitoring) and terminology

  • Experience collaborating with sitesfrominitialengagementthrough close-out phases

  • Experience activating sites

  • Experience training site staff

  • Experience supporting sites and/or sponsors in regulatory inspections

  • Experience working within a Functional Services (or in-house) monitoring model is preferred

  • Willing to travel up to 50%


Employment with ICON is contingent upon having the legal right to work in the country where the role is based.


Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.


Benefits may include:

  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.


Visit our careers site to read more about the benefits ICON offers.


Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.


If you require reasonable accommodations during the recruitment process, please let us know or submit a requesthere.

Are you a current ICON Employee? Please click here to apply

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