Position Details:
Our client, a world-leading Pharmaceutical Company in Spring House, PA is currently looking for a LCMS Scientist to join their expanding team.
Job Title: LCMS Scientist
Duration: 8 months contract, extendable up to 24 Months
Location: Spring House, PA
Note:
The client has the right-to-hire you as a permanent employee at any time during or after the end of the contract.
You may participate in the company group medical insurance plan
Description:
Overview
Be a part of a team developing state-of-the-art automation systems for mass spectrometry applied to biotherapeutics cell line development.
This role will leverage and develop the next phase of automation development in mass spectrometry supporting the Cell Engineering and Analytical Sciences group.
The role blends hands-on robotic operations, sample preparation, method development, and data analysis.
Notes:
Role is onsite 100% in Spring House, PA
Role is for 1 year at this time, regular business hours, NO TRAVEL
Bachelors degree is required
Mass spectometry required
LC-MS and sample prep required
Analyzing peptide mapping experience
Must have general lab skills
Will do programming, automation, but mass spectometry is required
Must have a willingness to learn and must be capable of learning
Will be managing samples D2D on mass spectometry
Experience with electronic lab notebooks
Must have Excel experience
Experience with Python, JavaScript, R
Must have a little industry experience
Top 2 Skills:
Mass spectometry
LC-MS experience
Job Description
Operating and validating robotic runs; monitoring performance, documenting deviations, and driving corrective action.
Develop and implement mass spectrometry assays to optimize protein expression levels, protein quality, and quantitation of biotherapeutics. Ensure accuracy and success of MS experiments through expertise in sample preparation.
Deploying, optimizing, maintaining, and continuously improving high-throughput workflows using liquid-handling robots and integrated automation workcells.
Analyze antibodies using peptide mapping, intact mass analysis, native mass spectrometry, and acoustic ejection mass spectrometry.
Troubleshooting instrumentation by coordinating with internal subject matter experts and external vendors to perform root cause analysis based on detailed scientific and technical investigations
Prepare and present scientific findings and recommendations to internal customers, project teams, and senior management.
Qualifications
Creative, independent problem‑solver with strong attention to detail and the ability to plan, prioritize, and deliver in a fast‑paced environment.
A minimum of a B.S. in Biology, Chemistry, Computer Science, Engineering, or a related field is requited. An advanced degree is preferred.
Strong organizational, time management, and interpersonal skills (both written and oral), and a commitment in close collaboration with scientists, vendors, and end users across seniority levels.
Previous hands on experience with executing protocols, pipetting and protein sample handling skills.
Experience with operating liquid handling systems (e.g., Hamilton, Tecan, Beckman) and/or basic programming experience (Python, JavaScript, R, C++/C#).
Hands on experience with LC-MS and associated sample preparation.