1

Contamination Control Engineer Jobs in California

Project Engineer - Facilities

Fremont, CA · On-site

$81K - $104K/yr

Maintain cleanroom and contamination control standards where applicable. * Support internal and ... Bachelor's degree in Mechanical Engineering, Electrical Engineering, Construction Management ...

Lead Optical Engineer

Irvine, CA · On-site

$139K - $179K/yr

... contamination control, and alignment processes. * Analyze test data and troubleshoot optical ... Bachelor's or Master's degree in Optical Engineering, Physics/Electrical Engineering or a related ...

Lead Optical Engineer

Irvine, CA

$138K - $179K/yr

... contamination control, and alignment processes. * Analyze test data and troubleshoot optical ... Bachelor's or Master's degree in Optical Engineering, Physics/Electrical Engineering or a related ...

Lead Optical Engineer

Irvine, CA · On-site

$139K - $179K/yr

... contamination control, and alignment processes. * Analyze test data and troubleshoot optical ... Bachelor's or Master's degree in Optical Engineering, Physics/Electrical Engineering or a related ...

... contamination control, energy consumption, and cycle times. · Lead troubleshooting efforts for hydraulic equipment failures, identifying root causes and implementing corrective and preventive ...

Partner across Quality, Manufacturing, Validation, Engineering, Supply Chain, and Technical ... Maintain effective microbiological control, environmental monitoring, and contamination control ...

Showing results 41-60

Contamination Control Engineer information

See California salary details

$54.3K

$95.3K

$129.3K

How much do contamination control engineer jobs pay per year?

As of Sep 13, 2026, the average yearly pay for contamination control engineer in California is $95,309.00, according to ZipRecruiter salary data. Most workers in this role earn between $82,400.00 and $106,600.00 per year, depending on experience, location, and employer.

What is a contamination control engineer?

A Contamination Control Engineer is responsible for identifying, mitigating, and preventing contamination in controlled environments such as cleanrooms, manufacturing facilities, and laboratories. They develop and enforce protocols to control particles, microbes, and other contaminants that could impact product quality and safety. Their role often involves collaborating with cross-functional teams to ensure compliance with industry regulations and standards. Additionally, they conduct risk assessments, implement contamination control strategies, and oversee facility cleanliness to maintain optimal working conditions.

What are the key skills and qualifications needed to thrive as a contamination control engineer?

A successful Contamination Control Engineer typically holds a degree in engineering or a related scientific field and possesses expertise in contamination control protocols, cleanroom practices, and environmental monitoring. Familiarity with relevant standards (such as ISO 14644), particulate and microbial detection systems, and certification in contamination control or cleanroom operations are often essential. Excellent attention to detail, problem-solving abilities, and strong communication skills help these engineers implement rigorous protocols and collaborate with multidisciplinary teams. These competencies are crucial to ensuring compliance with regulatory requirements, maintaining product quality, and protecting critical manufacturing or laboratory environments from contamination risks.

What are the typical challenges faced by contamination control engineers in the workplace?

Contamination Control Engineers often encounter the challenge of identifying and mitigating sources of particulate and microbial contamination in highly regulated environments such as pharmaceutical, semiconductor, or aerospace facilities. They must stay updated with evolving industry standards and continuously optimize processes despite changes in production or facility design. Collaboration with quality assurance, production, and facilities teams is routine, requiring strong communication to implement preventive measures effectively. These challenges can be rewarding, as overcoming them is essential to ensuring product quality, regulatory compliance, and a safe working environment.

What are popular job titles related to Contamination Control Engineer jobs in California?

For Contamination Control Engineer jobs in California, the most frequently searched job titles are:

What job categories do people searching Contamination Control Engineer jobs in California look for?

The top searched job categories for Contamination Control Engineer jobs in California are:

What cities in California are hiring for Contamination Control Engineer jobs?

Cities in California with the most Contamination Control Engineer job openings:

Infographic showing various Contamination Control Engineer job openings in California as of September 2026, with employment types broken down into 1% As Needed, 73% Full Time, 22% Part Time, 1% Temporary, 2% Contract, and 1% Nights. Highlights an 93% Physical, 1% Hybrid, and 6% Remote job distribution, with an average salary of $95,309 per year, or $45.8 per hour.

Senior Director, Cell Therapy Manufacturing Network F&E Lead

Los Angeles, CA • On-site

Astrazeneca
Pharmaceutical Product Wholesalers • 10K+ employees

$185K - $278K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 29 days ago


AstraZeneca rating

8.4

Company rating: 8.4 out of 10

Based on 45 frontline employees who took The Breakroom Quiz


Job description

You will

  • Establish user requirements and facility design standards for cell therapy manufacturing;develop risk-based contamination control approaches that account for open and closed processing, personnel gowning regimes, environmental monitoring, and the unique biological risks inherent in patient-derived cellular materials

  • Collaborate with Global Real Estate and Engineering to evaluate network expansion opportunities; provide cell therapy-specific input on site selection criteria, facility requirements, infrastructure needs, and operational considerations

  • Provide input to and/or leadengineeringstudiesto inform capital investment decisions, site master planning,newtechnologyadoptionor platform changes

  • Provide input to andparticipatein the established capital execution governance framework,planningand reporting

  • Lead identification and assessment of facility-related risks across existing sites and new-build programs,single points of failure in critical utilities, environmental control gaps,safetyand infrastructurerisksand develop mitigationstrategies that inform capital prioritization and operational decisions

  • Harmonize F&E operating models across existing supply sites byidentifyingopportunities for standardization, shared processes, common resource models,operatingcostsand aligned ways of working; develop a roadmap to bring consistency without disrupting ongoing operations

  • Support development and deployment of Digital and AI solutions for Facilities & Engineering across the supply network

  • Support implementation ofnew technologyfor existing F&E site teams-including training, resource planning, and adoption playbooks

  • Support SHE management review based on data inputs from the supply sites;identifytrends, compliance gaps, and improvement opportunities across the network;

  • Provide input tocell therapy specificsustainability initiatives aligned with corporatestrategy

You have

  • Education:Bachelor's degree in engineering(Mechanical, Chemical, Civil/Structural, or Architectural Engineering);Master'sdegree preferred; professional engineering licensure (PE/CEng) desirable

  • Experience: Minimum 10 years in pharmaceutical/biotech facilities engineering with at least 5 years in a network, multi-site, or above-site role; direct experience with celltherapy, biologics, or ATMP manufacturing facility design strongly preferred; demonstrated experience developing user requirements and design standards for GMP facilities; involvement in greenfield or major expansion programs from conceptual design through operational handover

  • Technical Knowledge: Expert knowledge of contamination control strategy for aseptic and cell therapy environments, cleanroom design (ISO classifications), pharmaceutical HVAC systems, GMP facility requirements, Engineering Studies, and commissioning/qualification protocols; familiarity with sustainability frameworks and current regulatory expectations for cell therapy facility design

  • Skills: Engineering judgment, contamination control risk assessment, ability to develop standards and requirements, cross-functional collaboration, stakeholder influence across sites and the ability to translate manufacturing operational needs into facility design requirements; comfortable operating in a support and input role within matrixed governance structures

  • Systems: Familiarity with BIM (Building Information Modeling), CMMS (Computerized Maintenance Management Systems), environmental monitoring systems, and energy management platforms.

The annual base pay for this position ranges from $185,000 to $278,000. Our positions offer eligibility for multiple incentives an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

05-Aug-2026

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.


What AstraZeneca employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom


AstraZeneca logo

About AstraZeneca

Sourced by ZipRecruiter

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. A place built on courage, curiosity and collaboration - we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take smart risks that write the next chapter for our pipeline and Oncology team. Make a meaningful impact that brings real benefits to society. By applying your knowledge of data, you will help to redefine our industry and ultimately save lives. Work with experts who share a common goal: to accelerate the potential of medicines and the science of tomorrow.

Industry

Pharmaceutical product wholesalers and pharmaceutical and medicine manufacturing

Company size

10,000+ Employees

Headquarters location

Cambridge, Cambridgeshire, GB