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Computer System Validation Manager Jobs in Buffalo, NY

U-Haul

Field Computer Specialist

West Seneca, NY · On-site

$4.8K - $5.8K/mo

The position requires a valid driver's license with a clean driving record. A company-provided van ... PTI access control systems, including wiring & device installation, troubleshooting, etc Security ...

Premier Aerospace NY LLC dba EverFab

Be Seen First

Tool Crib Attendant

East Aurora, NY · On-site

$18 - $22/hr

Uses company computer systems to maintain tool inventory records. Job Duties · Review schedule for ... Manage used tooling, making decisions to inventory, regrind or scrap. · Review and tear down ...

New

Samco Technologies Inc

Project Manager

Buffalo, NY · On-site

Serve as Project Manager on projects including communications, schedule, cost review, departmental ... Maintain the SAGE100 computer system: item number creation and maintenance, description accuracy ...

TopBuild Corp.

CAD Designer

North Tonawanda, NY · On-site

$20 - $40/hr

The CAD Designer will work alongside an assigned Project Manager, Design Center Manager and Sales ... Have a valid driver's license. 3D Cad software experience is a plus. Customer Expectations: The CAD ...

Topbuild

CAD Designer

North Tonawanda, NY

$20 - $40/hr

The CAD Designer will work alongside an assigned Project Manager, Design Center Manager and Sales ... Have a valid driver's license. 3D Cad software experience is a plus. Customer Expectations: The CAD ...

Barry Wehmiller Group

CAD Designer

Alden, NY · On-site

$34/hr

Louis, Missouri, is a global leader in equipment, forming systems, and essential accessory products ... Conduct FEA (Finite Element Analysis) simulations to validate design integrity under operational ...

Paper Converting Machine

CAD Designer

Alden, NY · On-site

$34/hr

Louis, Missouri, is a global leader in equipment, forming systems, and essential accessory products ... Conduct FEA (Finite Element Analysis) simulations to validate design integrity under operational ...

GTI Fabrication

Generator Systems Engineer

Buffalo, NY · On-site

$95K - $132K/yr

Participate in prototype builds, heat runs, system validation, and production troubleshooting ... management, cooling systems, or heat rejection design * Proficiency with CAD tools such as ...

Freseniusglobal

LIMS Administrator

Grand Island, NY · On-site

$60K - $85K/yr

Job Summary The Laboratory Information Management System (LIMS) Administrator is responsible for ... Supports Global validation and maintenance of the core system * Troubleshoot issues and ensure ...

Fresenius Kabi

LIMS Administrator

Grand Island, NY · On-site

$60K - $85K/yr

Job Summary The Laboratory Information Management System (LIMS) Administrator is responsible for ... Supports Global validation and maintenance of the core system * Troubleshoot issues and ensure ...

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All JobsComputer System Validation JobsComputer System Validation Manager JobsComputer System Validation Manager Jobs in Buffalo, NY

Computer System Validation Manager information

See Buffalo, NY salary details

$46K

$102.1K

$155.5K

How much do computer system validation manager jobs pay per year?

As of Jul 17, 2026, the average yearly pay for computer system validation manager in Buffalo, NY is $102,112.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,200.00 and $127,900.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Computer System Validation Manager, and why are they important?

To thrive as a Computer System Validation Manager, you need expertise in computer system validation regulations (such as GxP, FDA 21 CFR Part 11), strong project management skills, and a background in life sciences or IT. Familiarity with validation lifecycle documentation tools, quality management systems (QMS), and compliance software is often required, along with relevant certifications like PMP or CSV-related credentials. Exceptional attention to detail, analytical thinking, and effective communication are crucial soft skills for coordinating cross-functional teams and ensuring regulatory compliance. These skills and qualifications are vital to ensure validated systems meet regulatory standards, minimize compliance risks, and support organizational quality objectives.

What are some common challenges a Computer System Validation Manager faces during system implementation projects?

A Computer System Validation Manager often encounters challenges such as aligning validation activities with evolving regulatory requirements, managing tight project timelines, and coordinating between multiple stakeholders like IT, Quality Assurance, and business users. Ensuring thorough documentation and traceability, while adapting to technology updates or scope changes, can also be demanding. Proactive communication and strong project management skills are essential to mitigate risks and ensure successful, compliant system implementations.

What does a Computer System Validation Manager do?

A Computer System Validation Manager is responsible for ensuring that computer systems used in regulated industries, such as pharmaceuticals or biotechnology, meet all required compliance standards. They oversee the planning, execution, and documentation of validation activities to ensure systems are reliable, accurate, and secure. Their duties include managing validation projects, writing protocols, coordinating with IT and quality assurance teams, and ensuring adherence to regulations like FDA 21 CFR Part 11. This role is critical for maintaining product quality and regulatory compliance.

What is the difference between Computer System Validation Manager vs Computer System Validation Specialist?

AspectComputer System Validation ManagerComputer System Validation Specialist
CertificationsGAMP, CQE, CSQEGAMP, CQE, CSQE
Work EnvironmentManagement, oversight, strategic planningExecution, testing, documentation
Industry UsagePharmaceutical, biotech, regulated industriesPharmaceutical, biotech, regulated industries
Primary FocusLeading validation projects, team coordinationPerforming validation activities, testing

The main difference between a Computer System Validation Manager and a Computer System Validation Specialist lies in their roles. The manager oversees validation projects, manages teams, and ensures compliance, while the specialist executes validation tasks and documents testing procedures. Both roles require similar certifications and are vital in regulated industries like pharmaceuticals and biotech.

What are the most commonly searched types of Computer System Validation jobs in Buffalo, NY? The most popular types of Computer System Validation jobs in Buffalo, NY are:
What are popular job titles related to Computer System Validation Manager jobs in Buffalo, NY? For Computer System Validation Manager jobs in Buffalo, NY, the most frequently searched job titles are:
What job categories do people searching Computer System Validation Manager jobs in Buffalo, NY look for? The top searched job categories for Computer System Validation Manager jobs in Buffalo, NY are:
What cities near Buffalo, NY are hiring for Computer System Validation Manager jobs? Cities near Buffalo, NY with the most Computer System Validation Manager job openings:
Computer System Validation Manager jobs near you
Infographic showing various Computer System Validation Manager job openings in Buffalo, NY as of July 2026, with employment types broken down into 1% As Needed, 81% Full Time, 16% Part Time, and 2% Contract. Highlights an 82% Physical, 1% Hybrid, and 17% Remote job distribution, with an average salary of $102,112 per year, or $49.1 per hour.
Validation Specialist II

Validation Specialist II

Pine Pharmaceuticals

Tonawanda, NY

Full-time

Re-posted 29 days ago

Job description

Position Summary:

Works collaboratively with the Quality Control and Production Unit to perform routine validation and calibration activities. Assists with onboarding of all new equipment, requalification of existing equipment and all validation activities to include Installation and Operational Qualifications and Performance Qualifications.


Essential Functions:

  • Perform and assist with validation activities such as Installation,Operational, Performance Qualifications (IOPQ), and Requalifications (RQ).
  • Author and review of technical documents such asqualification protocols, summary reports, and final reports.
  • Support computer system validation activities including user acceptance testing, traceability documentation, and validation summary reports.
  • Assist in nonconformance investigations, out-of-specification (OOS), and out-of-calibration (OOC) events as they relate to validated systems and equipment.
  • Support risk assessment activities associated with equipment qualification, process changes, and revalidation decisions.
  • Creation and modification of SOP's to reflect current validated status
  • Setup and operation of dataacquisitiondevices such as the Kaye Validator and Eupry dataloggers.
  • Assist as required in troubleshooting validated equipmentsuch as autoclaves, refrigerators, freezers, incubators, labelingequipment, etc.
  • Maintain oversight ofthe internal calibration tracking program by maintaining the records and alerting key stakeholders of calibration due dates and status
  • Collaborate with key stakeholders to assist in new validation initiatives
  • Perform other duties assigned by the Director of Engineering and Director of Quality/Production to ensure uniform quality assurance throughout the entire company
  • Become gown qualified to perform validation activities in classified environments

Education and Experience:

  • A minimum of 1-2 years Validations or equivalent experience
  • Aminimum ofa 2 or 4 yeardegree, preferably in a Science or Engineering field of study; or equivalent industry experience.

Knowledge, Skills and Abilities:

  • Full knowledge and understanding of FDA cGMP, CFR Parts 210 and 211, USP Chapters / Monographs, and various State Board of pharmacy laws as they relate tothe HumanDrug Compounding.
  • Excellent interpersonal communication skills including presentation skills, and multitask ability
  • Strong computer skills, knowledgeable with standard Microsoft Office applications and Kaye Validator software
  • Self-motivated and organized with minimum supervision
  • Cleaning validation experience desirable


Physical Requirements / Working Conditions:

  • Prolonged periods standing on production floor
  • Prolonged periods of walking
  • Must be able to lift up to 35 pounds at times
  • Must be able to climb small stepladders
  • Must be able to wear appropriate PPE (goggles, gloves, scrubs, frock/coverall, hairnet/hood, beard guard/mask) as needed based on work area and materials being handled in accordance with procedures/policies


Compensation

$65-$80K/yr DOE

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