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Computer Information System Manager Jobs in Frederick, MD

Customer Value Partners

Risk Manager

Rockville, MD · On-site

The Cybersecurity Risk Manager will work directly with the Cybersecurity Program Manager and the ... system authorization; security reporting; and other information security-related tasks.

Customer Value Partners

Risk Manager

Rockville, MD · On-site

The Cybersecurity Risk Manager will work directly with the Cybersecurity Program Manager and the ... system authorization; security reporting; and other information security-related tasks.

Customer Value Partners

Risk Manager

Rockville, MD

$155K - $165K/yr

The Cybersecurity Risk Manager will work directly with the Cybersecurity Program Manager and the ... system authorization; security reporting; and other information security-related tasks.

Customer Value Partners

Risk Manager

Rockville, MD · On-site

Track the A&A status for all divisions and programs that have information systems to validate they ... Certified Information Security Manager (CISM) * Certified in Risk and Information Systems Control ...

X Energy, LLC

Manager, IT Projects

Rockville, MD

$100K - $118K/yr

IT Project Manager This role will provide project management for Digital Engineering IT projects ... systems including Teamcenter, NX CAD integration, and Product Lifecycle Management * Detail and ...

CAI

Computer Systems Validation Engineer

Rockville, MD · On-site

$75K - $106K/yr

We provide commissioning, qualification, validation, startup, project management, and other ... System & Industry Expertise Support CSV activities across various platforms including MES, DCS ...

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All JobsComputer Information System JobsComputer Information System Manager JobsComputer Information System Manager Jobs in Frederick, MD

Computer Information System Manager information

See Frederick, MD salary details

$21.4K

$99.6K

$150.1K

How much do computer information system manager jobs pay per year?

As of Jun 15, 2026, the average yearly pay for computer information system manager in Frederick, MD is $99,623.00, according to ZipRecruiter salary data. Most workers in this role earn between $78,000.00 and $121,300.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Computer Information System Manager position, and why are they important?

To excel as a Computer Information System Manager, you typically need a bachelor’s degree in computer science or information systems, alongside strong leadership and project management capabilities. Familiarity with enterprise resource planning (ERP) software, network infrastructure, cybersecurity tools, and relevant certifications like PMP or CISSP is highly valued. Outstanding communication, problem-solving, and organizational skills help facilitate collaboration among IT teams and other departments. These competencies ensure efficient system operations, secure data management, and successful project delivery in dynamic business environments.

What does a Computer Information System Manager do?

A Computer Information System (CIS) Manager oversees an organization's technology infrastructure, ensuring systems run efficiently and securely. They manage IT teams, implement new technology solutions, and troubleshoot technical issues. CIS Managers also develop IT policies, coordinate system upgrades, and align technology with business goals to enhance productivity and security.

What are the typical daily responsibilities of a Computer Information System Manager?

As a Computer Information System Manager, your typical day involves overseeing IT infrastructure, managing system upgrades and maintenance, and ensuring data security across the organization. You’ll coordinate projects, troubleshoot system issues, and work closely with department heads to align technical solutions with business needs. The role often requires balancing both hands-on technical work and strategic management, including supervising IT staff and vendors. Regular collaboration and clear communication are essential, as you’ll serve as the primary liaison between technical teams and organizational leadership to drive technology-related initiatives.

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Computer Information System Manager jobs near you
Computer Systems Validation Lead

Computer Systems Validation Lead

Quality Agents, LLC

Rockville, MD

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 14 days ago

Job description

Quality Agents, LLC offers validation and quality expertise to the pharmaceutical and biotechnology industries.


Our Computer Systems Validation Leads work directly with our clients to support activities that include, but are not limited to, documentation review and approval, including change controls, assessment plans, risk assessment reports, compliance plans, user requirements, system and user acceptance testing protocols, traceability matrix, error reports/defect report forms and summary reports. The individual will contribute directly to the completion of projects through the management of assigned contract personnel, development and execution of validation change control documents, and development and review of protocols, reports and data tables generated by peers and contract personnel. Responsibilities include:


  • Optimization of CQV support process, including developing including developing standards and KPI reports.
  • Compile and analyze validation data and make recommendations for changes and/or improvements
  • Maintain all documentation pertaining to computer systems validation
  • Data integrity qualification
  • Participate in cross-functional project teams including development & deployment teams as well as customer Manufacturing, Engineering, Quality and other groups
  • Some travel is required


Skill level & requirements:


  • Experience with IQ, OQ, PQ Final reports relating to Computer Systems Validation.
  • Experience writing validation master plans.
  • Experience with Configuration, design, data and traceability matrices.
  • Validation experience with automated systems is preferred
  • Thorough knowledge of cGMP regulations related to CSV including 21 CFR Part 11
  • Strong knowledge of computerized system development life cycle approach is required
  • Strong leadership skills and the ability to work in cross-functional team environments, as well as independently
  • Experience coordinating Quality documentation, specifically qualification/Validation documentation
  • Demonstrated excellent leadership/Project Manager skills
  • Strong technical writing skills
  • Excellent written and verbal communication skills
  • The ability to work and make decisions independently and have the flexibility to adapt to changing priorities is required


Minimum Requirements:


  • Bachelor's degree in a technical discipline (i.e. Engineering, Chemistry, Microbiology, Biology)
  • 3 - 5 years Computer Systems Validation background
  • 3 - 5 years IT Quality Assurance / Validation experience
  • Current driver's license and auto insurance or other means of independent transportation


Quality Agents offers a full suite of benefits for full-time employees including:


  • Health, dental and vision insurance
  • Life, AD&D and Disability Insurance
  • Health savings account for participants in our health plan
  • 401k retirement plan
  • Paid time off
  • Paid holidays


Quality Agents accepts applications on an on-going basis in order to build a talent pool of potential candidates. These applications remain open for consideration, as positions become available, for one (1) year from the date of application.After that time, or if your application information changes, please submit your application again.

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