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Computational Spatial Transcriptomics Jobs in Texas

Spatial transcriptomics * Proteomics * Metabolomics * Multi-omics integration analyses * Develops ... Mentors graduate students and other trainees in computational biology approaches. * Contributes to ...

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Computational Spatial Transcriptomics information

What is computational spatial transcriptomics?

Computational spatial transcriptomics is a field that combines advanced computational methods with spatial transcriptomics, a technique that measures gene expression within the physical context of tissue samples. It involves processing and analyzing large datasets to map where specific genes are active within tissues, helping researchers understand how cells interact and function in their native environments. This approach is crucial for studies in developmental biology, cancer research, and neuroscience, as it provides insights into cellular organization and tissue architecture. Computational tools help extract meaningful patterns from complex data, enabling discoveries that were previously impossible with traditional methods.

What are some typical challenges faced when working in computational spatial transcriptomics, and how can new team members prepare for them?

Professionals in computational spatial transcriptomics often encounter challenges related to handling and analyzing large, complex datasets that combine spatial and gene expression information. Integrating data from different technologies and ensuring data quality can be demanding, requiring strong programming skills and familiarity with bioinformatics pipelines. New team members can prepare by strengthening their skills in statistical analysis, programming languages like Python or R, and staying updated on the latest spatial transcriptomics techniques. Collaborating closely with experimental biologists and data scientists is also key to overcoming these challenges and driving successful research outcomes.

What are the key skills and qualifications needed to thrive as a computational spatial transcriptomics scientist, and why are they important?

To excel in Computational Spatial Transcriptomics, you need a strong background in bioinformatics, genomics, and statistical data analysis, typically supported by advanced degrees in computational biology or related fields. Familiarity with programming languages (such as R and Python), spatial transcriptomics platforms (like 10x Genomics Visium), and high-throughput sequencing data analysis tools is essential. Strong problem-solving skills, attention to detail, and effective communication are crucial soft skills for interpreting complex datasets and collaborating with multidisciplinary teams. These competencies ensure accurate data interpretation, innovative research, and successful integration of spatial transcriptomics insights into biological and clinical applications.

What is the difference between Computational Spatial Transcriptomics vs Computational Biologist?

AspectComputational Spatial TranscriptomicsComputational Biologist
Required CredentialsAdvanced degrees in bioinformatics, computational biology, or related fields; experience with spatial data analysisTypically a PhD or Master's in biology, bioinformatics, or related disciplines; strong programming skills
Work EnvironmentResearch labs, biotech companies, academic institutions focusing on spatial genomicsResearch institutions, biotech firms, academia working on biological data analysis
Industry UsageSpecialized in spatial transcriptomics techniques and data interpretationBroad biological data analysis across various fields

Computational Spatial Transcriptomics focuses on analyzing spatial gene expression data within tissues, requiring specialized skills in spatial data processing. In contrast, Computational Biologists work on a wider range of biological data types. While both roles involve bioinformatics expertise, the former emphasizes spatial data analysis techniques specific to transcriptomics.

What job categories do people searching Computational Spatial Transcriptomics jobs in Texas look for?

The top searched job categories for Computational Spatial Transcriptomics jobs in Texas are:

What cities in Texas are hiring for Computational Spatial Transcriptomics jobs?

Cities in Texas with the most Computational Spatial Transcriptomics job openings:

Infographic showing various Computational Spatial Transcriptomics job openings in Texas as of August 2026, with employment types broken down into 1% Internship, 60% Full Time, 38% Part Time, and 1% Contract. Highlights an 50% Physical, 2% Hybrid, and 48% Remote job distribution.

POSTDOCTORAL RESEARCHER-Biomedical Data Science & AI-Epidemiology-Ruan Lab [Req#: 963199, Position#:

Dallas, TX • On-site


UT Southwestern Medical Center
Hospitals • 10K+ employees

7.9

Company rating: 7.9 out of 10

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Full-time

Posted 21 days ago


Job description

Description
POSTDOCTORAL RESEARCHER
A postdoctoral fellow position is now available in the laboratories of Dr. Peifeng Ruan (https://qbrc.swmed.edu/labs/ruanlab/) at the Quantitative Biomedical Research Center (QBRC) in the Peter O'Donnell Jr. School of Public Health at UT Southwestern Medical Center, Dallas. The labs' research focuses on developing and applying advanced computational and AI methods to address critical challenges in biomedical research and clinical practice.
The training activities of this position will include data management, curation, and analysis of large-scale biomedical and clinical datasets, including proteomics, metabolomics, single-cell transcriptomics and spatial transcriptomics data; development and/or implementation of novel statistics, machine learning and AI approaches; integration of molecular, cellular, spatial, imaging, and clinical data; interpretation and presentation of analysis results; and writing manuscripts. We are actively seeking exceptionally motivated individuals with outstanding problem-solving abilities. In this role, you will conduct cutting-edge research at the intersection of artificial intelligence and biomedical sciences, with opportunities to collaborate with clinical investigators and industry partners.
Information on our postdoctoral training program, benefits, and a virtual tour can be found at https://www.utsouthwestern.edu/research/postdoctoral-scholars/.
Qualifications
Candidates with a Ph.D. in computer science, bioinformatics, data science, machine learning, or a related quantitative field are encouraged to apply. Experience with one or more of the following areas is desirable: single-cell transcriptomics and spatial transcriptomics, knowledge graphs, large language models, or analysis of real-world clinical data (e.g., electronic health records, claims databases, or pharmacovigilance databases).
Application Instructions
Interested individuals should send a CV and a list of three references to:
Peifeng Ruan
Peifeng.Ruan@UTSouthwestern.edu


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