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Computational Biologist Jobs in Minnesota (NOW HIRING)

Mayo Clinic

Research Fellow - Neurology

Rochester, MN · On-site

$64K - $74K/yr

... computational scientists. A Research Fellow at Mayo Clinic is a temporary position intended to ... Must have a Ph.D., M.D., or equivalent doctoral degree in neuroscience, cell biology ...

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Computational Biologist information

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$47.5K

$92.1K

$130.8K

How much do computational biologist jobs pay per year?

As of Sep 1, 2026, the average yearly pay for computational biologist in Minnesota is $92,053.00, according to ZipRecruiter salary data. Most workers in this role earn between $69,000.00 and $114,600.00 per year, depending on experience, location, and employer.

What is a computational biologist?

A computational biologist is a skilled scientist who uses complex computer algorithms to research and analyze biological systems. This highly specialized job entails using computers and advanced data analytics software to research biological topics such as genetic sequencing, cellular growth numbers, and protein sampling. As a computational biologist, your duties are to code computer algorithms and perform bioinformatics research in the lab. You may also work with students by using the data from their bioinformatics research.

What are the key skills and qualifications needed to thrive as a computational biologist, and why are they important?

To thrive as a Computational Biologist, you need a strong background in biology, mathematics, statistics, and computer science, often supported by an advanced degree in a relevant field. Proficiency with programming languages (such as Python or R), bioinformatics tools, and data analysis platforms is essential. Strong problem-solving abilities, attention to detail, and effective communication are standout soft skills for this role. These skills are critical for analyzing complex biological data, interpreting results, and collaborating with multidisciplinary teams to advance scientific research.

What are some common interdisciplinary collaborations for a computational biologist, and how do these impact daily work?

Computational Biologists frequently collaborate with laboratory scientists, statisticians, and software engineers to analyze complex biological data. These interdisciplinary interactions mean that communication skills are essential, as you’ll often translate computational findings into actionable insights for experimental teams. Daily responsibilities may include attending joint meetings, discussing data analysis strategies, and integrating feedback from collaborators to refine models. This collaborative environment fosters both scientific discovery and personal growth, offering exposure to diverse perspectives and expertise.
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Computational Biologist jobs near you
Infographic showing various Computational Biologist job openings in Minnesota as of August 2026, with employment types broken down into 71% Full Time, 26% Part Time, 1% Temporary, and 2% Contract. Highlights an 73% Physical, 2% Hybrid, and 25% Remote job distribution, with an average salary of $92,053 per year, or $44.3 per hour.

RTP - Research Fellow - AI and Informatics

Mayo Clinic

Rochester, MN • On-site

Full-time

Medical, Dental, Vision, Retirement

Re-posted 24 days ago

Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 705 frontline employees who took The Breakroom Quiz

134th of 898 rated healthcare providers

Job description


A Research Fellow opportunity is available under the mentorship of Hao Gong, Ph.D. in the Research Department of AI and Informatics.
A Research Fellow in Engineering in this role will apply advanced computational and engineering skills to the development, implementation, and evaluation of AI / ML algorithms for clinical applications. Responsibilities include processing and analyzing imaging and multimodal clinical data, implementing and testing of computational models, and supporting translational research and clinical deployment within an interdisciplinary environment.
A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic.
Qualifications
The Research Fellow will lead the development and validation of advanced AI / ML algorithms to support diagnosis and treatment planning, work closely with clinical collaborators to translate in-house-developed techniques toward clinical adoption, and disseminate significant scientific findings through conference presentations and peer-reviewed publications. Applicants should have a strong background in clinical image processing and analysis, generative modeling, multi-modal learning, experimental design, and statistical evaluation. Additional domain knowledge in clinical imaging physics or computational biology is considered a plus.
  • Ph.D. degree in Computer Science, Electrical and Computer Engineering, Biomedical Engineering, Applied Mathematics, Medical Physics, or a related field.
  • Extensive expertise in developing advanced AI / ML methods for clinical imaging tasks, such as disease classification, lesion detection, lesion / tumor segmentation, and biomarker analysis.
  • Proven, hands-on experience with generative modeling approaches (e.g., GAN, Diffusion, or LLM).
  • Experience of designing or implementing multi-modal frameworks that integrate imaging data with other modalities (e.g., EHRs, genomics, clinical reports).
  • Excellent Python programming skills are required, with proficiency in TensorFlow / PyTorch and modern ML tools.
  • (Preferred) Experience with scalable computing, such as multi-GPU training, distributed data processing, and research-oriented MLOps.
  • Excellent oral and written English communication skills, along with a solid record of peer-reviewed publications in relevant conferences and academic journals.
  • The ability to work independently and collaboratively within a multidisciplinary environment.

About Us
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

About the Team
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

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About Mayo Clinic

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Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919

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