ZipRecruiter

Log In

1

Cmc Main Jobs in California (NOW HIRING)

previous pagenext page

Showing results 21-40

All JobsCmc Main JobsCmc Main Jobs in California

Cmc Main information

What is a CMC Main?

CMC Main jobs typically refer to roles within the Correctional Management Complex (CMC) at a correctional or detention facility. These positions may include correctional officers, administrative staff, medical personnel, and support staff responsible for maintaining security, supervising inmates, managing facility operations, and providing rehabilitative services. The 'Main' designation often distinguishes the primary or central facility from annexes or satellite units. Working in CMC Main requires strong communication, observation, and crisis management skills, as well as the ability to work in a challenging environment. These roles are essential for the safety and orderly operation of correctional institutions.

What are some common challenges faced by CMC professionals in maintaining regulatory compliance during product development?

A key challenge for CMC professionals is staying current with evolving global regulatory requirements, as these can differ significantly between regions. They must ensure thorough documentation and consistency in manufacturing processes, which involves collaborating closely with quality assurance, regulatory affairs, and R&D teams. Managing timelines and resources efficiently while responding to regulatory feedback is also crucial. Successfully navigating these challenges not only supports product approval but also minimizes costly delays.

What are the key skills and qualifications needed to thrive as a CMC Maintenance Technician, and why are they important?

To excel as a CMC Maintenance Technician, you need strong mechanical aptitude, troubleshooting abilities, and typically a relevant technical diploma or certification. Familiarity with computerized maintenance management systems (CMMS), diagnostic tools, and safety protocols is essential. Attention to detail, effective communication, and the ability to work well under pressure are valuable soft skills in this role. These competencies are crucial for ensuring equipment reliability, minimizing downtime, and maintaining a safe, efficient work environment.

What is the difference between Cmc Main vs Cmc Coordinator?

AspectCmc MainCmc Coordinator
CredentialsTypically requires advanced degrees or extensive experience in pharmaceutical or biotech industriesOften requires basic certifications or relevant experience, but less specialized
Work EnvironmentInvolves overseeing CMC activities, ensuring compliance, and managing teams in a regulated environmentFocuses on supporting CMC processes, coordinating documentation, and assisting senior staff
Industry UsageUsed in pharmaceutical, biotech, and life sciences companies for senior or lead rolesCommonly used for entry to mid-level roles supporting CMC functions

The main difference between Cmc Main and Cmc Coordinator lies in their responsibilities and required experience. Cmc Main roles involve overseeing and managing CMC activities with higher qualifications, while Cmc Coordinators support these processes with more administrative and coordination tasks. Both roles are essential in the pharmaceutical industry but differ in scope and seniority.

What are popular job titles related to Cmc Main jobs in California?

For Cmc Main jobs in California, the most frequently searched job titles are:

What job categories do people searching Cmc Main jobs in California look for?

The top searched job categories for Cmc Main jobs in California are:

Cmc Main jobs near you
Infographic showing various Cmc Main job openings in California as of August 2026, with employment types broken down into 17% As Needed, 49% Full Time, 17% Part Time, and 17% Contract. Highlights an 100% In-person job distribution.

Director Product Quality Leader

AstraZeneca

Santa Monica, CA • On-site

$167K - $251K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 16 days ago

AstraZeneca rating

8.4

Company rating: 8.4 out of 10

Based on 45 frontline employees who took The Breakroom Quiz

23rd of 86 rated pharmaceutical

Job description

The Cell Therapy Product Quality Leader (PQL) is a matrixed leader responsible for the end-to-end product quality strategy and lifecycle management of autologous, allogeneic, and in-vivo cell therapy products. This role will provide technical and compliance oversight for advanced therapeutic modalities, including, but not limited to, drug substance, drug product, viral delivery systems (e.g. LVV, AAV), and gene-edited cell therapy products from clinical stage through commercialization. This role requires deep technical and compliance expertise, strategic thinking, and cross-functional collaboration to ensure product quality, regulatory compliance, and lifecycle continuity are met and maintained.
This PQL position can physically reside at either the Gaithersburg/Rockville, MD site or Santa Monica/Tarzana, CA site locations, with an understanding that the products supported are manufactured at the Santa Monica/Tarzana, CA sites.
Main Responsibilities:
  • Serve as the Quality representative on the CMC Team and lead the Product Quality Team (PQT) sub-team

  • Serve as the single voice of Quality in liaising with the CMC Program Lead to communicate Quality deliverables, risks, changes, etc.

  • Develop and implement the overall Product Quality Strategy and phase-appropriate control strategies

  • Own and maintain lot release and stability specifications for advanced cell therapy modalities

  • Manage the full specification lifecycle - from clinical stage through commercial approval and post-approval maintenance

  • Support the design and execution of analytical comparability studies supporting process and product changes for advanced cell therapy modalities; ensure scientifically sound strategies and data-driven conclusions

  • Support the design and execution of process tech transfer and analytical method transfer protocols/reports for advanced cell therapy modalities

  • Oversee the stability program for advanced cell therapy modalities, in collaboration with Global Stability

  • Oversee annual product reviews for commercial products

  • Maintain the Product Quality Risk Register to identify, mitigate, and escalate issues related to manufacturing, analytical methods, or supply chain

  • Work cross-functionally to develop and implement platform approaches for specifications, comparability, and stability to enable consistent, scalable practices across multiple cell therapy products

  • Author and review CMC sections for global filings, including INDs, BLAs, and MAAs; manage responses to health authority queries

  • Stay current on emerging process & analytical technologies and evolving regulatory expectations

  • Partner closely with Process Development, Analytical Sciences, Supply Chain, Quality, Regulatory Affairs, Program Management, and other impacted stakeholders to ensure alignment with development milestones and commercial objectives

  • Acts as a Subject Matter Expert (SME) during health authority inspections (e.g., FDA, EMA) for product quality-specific inquiries

  • Review and evaluate major process changes to ensure no impact to product safety and efficacy

Education, Qualifications, & Experience:
  • Bachelor's or Advanced degree (MS/PhD preferred) in Life Sciences or Engineering (e.g., Biology, Biochemistry, Chemical Engineering)

  • 10+ years in the biotechnology or biopharmaceutical industry, with at least 3 - 5 years in a Cell & Gene Therapy (CGT) or Biologics leadership role

  • Deep understanding of global cGMP regulations (FDA, EMA, ICH) including phase-appropriate requirements for clinical vs. commercial products

  • Demonstrated record of authoring CTD sections for IND, BLA/MAA, and/or post-approval submissions

  • Expertise in analytical method validation, process development, tech transfer, and viral vectors (e.g. LVV)

  • Expertise in designing and executing product & process control and comparability strategies

  • Demonstrated ability to clearly articulate complex technical concepts to cross-functional, senior management, and regulatory audiences

  • Demonstrated success in a fast-paced, matrixed environment with a collaborative, problem-solving mindset, including an ability to influence diverse stakeholders and drive decision-making without direct authority

The annual base pay for this position ranges from $167,595.20 - 251,392.80. Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Date Posted
17-Aug-2026
Closing Date
03-Sep-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

What AstraZeneca employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

AstraZeneca logo

About AstraZeneca

Sourced by ZipRecruiter

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. A place built on courage, curiosity and collaboration - we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take smart risks that write the next chapter for our pipeline and Oncology team. Make a meaningful impact that brings real benefits to society. By applying your knowledge of data, you will help to redefine our industry and ultimately save lives. Work with experts who share a common goal: to accelerate the potential of medicines and the science of tomorrow.

Industry

Pharmaceutical product wholesalers and pharmaceutical and medicine manufacturing

Company size

10,000+ Employees

Headquarters location

Cambridge, Cambridgeshire, GB

View All AstraZeneca Jobs

Apply