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Clinical Trial Operation Manager Jobs (NOW HIRING)

WEP Clinical

Clinical Trial Project Manager

Provide day-to-day accountability for the operational delivery of assigned clinical trials ... Client & Stakeholder Management * Act as the primary client contact for clinical trial operations ...

Clinovo

Clinical Trial Manager

Cambridge, MA · On-site

The Clinical Trial Manager (CTM) plays a key role in the successful execution of clinical research studies, providing operational leadership from study initiation through final closeout. This ...

ICON

Clinical Trial Manager

Center Square, PA · On-site

Clinical Operations Lead ICON plc is a world-leading healthcare intelligence and clinical research ... As a Clinical Trial Manager at ICON, you will manage clinical trial operations activities ...

Prometrika, Llc

Clinical Trial Manager

Cambridge, MA · On-site

$140K - $168K/yr

Manage the operational aspects of clinical trials (e.g., study management, site monitoring and management, trial master file (TMF) oversight) * Coordinate and support regulatory submissions and ...

Biogen

Clinical Trial Manager

Cambridge, MA · On-site

$117K - $157K/yr

As a Clinical Trial Manager, you will be a vital part of the PO&T team within the Implantable ... Monitor study progress and operational metrics, identifying and escalating risks or issues ...

Biogen

Clinical Trial Manager

Cambridge, MA · Hybrid

$117K - $157K/yr

As a Clinical Trial Manager, you will be a vital part of the PO&T team within the Implantable ... Monitor study progress and operational metrics, identifying and escalating risks or issues ...

Intuitive

Clinical Trial Manager

San Carlos, CA · On-site

Clinical Operations & Execution * Manage end-to-end trial execution for assigned studies, including site identification/feasibility assessment, site initiation and activation, patient enrollment and ...

Prometrika LLC

Clinical Trial Manager

Cambridge, MA · On-site

$140K - $168K/yr

Manage the operational aspects of clinical trials (e.g., study management, site monitoring and management, trial master file (TMF) oversight,) * Coordinate and support regulatory submissions and ...

SAB

Clinical Trial Manager, Immunology

Miami Beach, FL · On-site

Manage all aspects of clinical trial operations, ensuring adherence to timelines, budgets, and regulatory requirements. * Participate in the identification, evaluation, selection, and oversight of ...

SAB

Clinical Trial Manager, Immunology

Miami Beach, FL · Remote

$150K - $165K/yr

Manage all aspects of clinical trial operations, ensuring adherence to timelines, budgets, and regulatory requirements. * Participate in the identification, evaluation, selection, and oversight of ...

SAB

Clinical Trial Manager, Immunology

Tulsa, OK · On-site

Manage all aspects of clinical trial operations, ensuring adherence to timelines, budgets, and regulatory requirements. * Participate in the identification, evaluation, selection, and oversight of ...

OCUGEN OPCO INC

Clinical Trial Manager

Malvern, PA · On-site

Own the study operational plan and ensure alignment with the scientific protocol and program goals. * Manage clinical timelines, enrollment projections, budget tracking, and risk mitigation ...

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How much do clinical trial operation manager jobs pay per hour?

As of Sep 12, 2026, the average hourly pay for clinical trial operation manager in the United States is $62.52, according to ZipRecruiter salary data. Most workers in this role earn between $50.72 and $70.43 per hour, depending on experience, location, and employer.

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Infographic showing various Clinical Trial Operation Manager job openings in the United States as of August 2026, with employment types broken down into 88% Full Time, 11% Part Time, and 1% Contract. Highlights an 85% Physical, 2% Hybrid, and 13% Remote job distribution, with an average salary of $130,034 per year, or $62.5 per hour.

Clinical Trial Project Manager

Remote

WEP Clinical
11 - 50 employees
Learn more about WEP Clinicalexternal

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 23 days ago

Job description

Are you looking for an exciting and fulfilling new position? Join our dynamic team at WEP Clinical, where your contributions will play a key role in driving impactful solutions and improving outcomes for clients and patients. We encourage innovation and collaboration, challenging our team to bring forward ideas that make a real difference. Be part of a mission-driven organization dedicated to advancing clinical research and transforming lives.
 
 
Role Objectives: 

The Clinical Project Manager at WEP Clinical is responsible for the setup, implementation, and management of clinical trials, ensuring patient safety, data integrity, and high-quality delivery in compliance with applicable regulations.

This role provides leadership across cross-functional teams, manages client relationships, and is accountable for delivering clinical trials on time, within scope, and within budget.

The Ideal Candidate:
  • Adaptable
  • Detail-oriented
  • Collaborative
  • Solutions-focused
What You'll Do:
The level of appointment (e.g., Project Manager II or Senior Project Manager) will be determined based on the candidate's experience, skills, and demonstrated capabilities during the interview process.
 
 
Principal Duties and Responsibilities
  • Lead the setup, execution, and close-out of clinical trials in compliance with WEP Clinical SOPs, GCP/ICH guidelines, and regulatory requirements.
  • Provide day-to-day accountability for the operational delivery of assigned clinical trials.
  • Develop and maintain study manuals, operational project plans, timelines, and key performance metrics.
  • Ensure proper setup, maintenance, and close-out of eTMF and CTMS systems.
Leadership & Cross-Functional Oversight
  • Serve as project team lead and primary point of contact for internal and external stakeholders.
  • Provide oversight and coordination of cross-functional deliverables including monitoring, site management, data management, pharmacovigilance, regulatory, IP supply, and medical writing.
  • Ensure internal and external teams are appropriately trained on study protocols and operational requirements.
Client & Stakeholder Management
  • Act as the primary client contact for clinical trial operations, deliverables, and issue resolution.
  • Lead internal and external meetings, ensuring alignment on project status, risks, and timelines.
Risk & Issue Management
  • Identify, assess, and proactively manage risks and issues throughout the clinical trial lifecycle.
  • Implement mitigation strategies and corrective actions where required.
Regulatory & Compliance
  • Oversee submissions to IRB/ECs and review informed consent forms as required.
  • Ensure compliance with regulatory requirements and internal quality standards.
  • Collaborate with Quality Assurance to support audits, CAPAs, and investigations as appropriate.
Financial & Vendor Management
  • Manage project budgets, scope, and financial performance.
  • Oversee vendor performance and deliverables, including review and approval of invoices.
  • Review site payments and ensure alignment with Clinical Trial Agreements.
Documentation & Systems
  • Maintain accurate and complete trial documentation within internal systems (e.g., SharePoint).
  • Ensure all trial records meet quality and compliance standards.
What You'll Need:
  • Bachelor's Degree (health or science field preferred)
  • Minimum 5 years' experience in a Project Manager role within clinical trials or clinical research 
  • Demonstrated experience managing clinical trials from initiation through close-out
  • Strong working knowledge of ICH GCP guidelines and clinical trial processes
  • Proven ability to lead cross-functional teams and manage multiple priorities
  • Strong organizational, problem-solving, and decision-making skills
  • Effective verbal and written communication skills
  • Proficiency in Microsoft Office tools
  • Ability and willingness to travel as required for business needs
Additional Notes
  • This role may be filled at different levels depending on experience and demonstrated capability.
  • Responsibilities may expand in scope with increased seniority and complexity of assigned projects.
Location eligibility applies. Candidates must reside in a U.S. state where the company is authorized to hire. This role is not eligible for residents of: California, Colorado, New York, Washington, New Jersey, Massachusetts, Illinois, Hawaii, and District of Columbia. 
 
What We Offer:
Medical, dental, and vision insurance
FSA, HSA
Voluntary Critical Illness, Hospital Indemnity, and Accident Insurance
Group short-term and long-term disability insurance
Group Life Insurance
401K safe harbor plan and company match
Paid vacation, holiday, sick and volunteer time
Paid maternity & paternity leave
 
What Sets Us Apart:
WEP Clinical partners with biopharmaceutical Sponsors to help them bring treatments closer to the patients who need them most. Through end-to-end clinical trial delivery, home health services, expanded access programs, and market access consultancy, we provide flexible, fit-for-purpose solutions that support drug development, improve access, and help therapies reach the right patients at the right time. With more than 15 years of global experience, we have supported programs across 150+ countries, combining operational scale with the agility and personalized service of a specialized provider. Our work helps bridge critical gaps in care, ensuring safe, ethical, and efficient access to promising new treatments. 
 
We're Committed to Our Team:
WEP has many initiatives to encourage wellness, growth and development, and team relationships. Check out our LinkedIn Life Page to learn more about our team events and all we do to support our employees. 
 
How We Work at WEP Clinical:
At WEP Clinical, we look for individualswho are conscientious, exercise sound judgment, and engage with others thoughtfully and professionally. We believe excellence is achieved through integrity, accountability, and respect for diverse perspectives - and we are committed to helping our people grow and succeed in an inclusive, supportive environment. 
 
Our Services Include:
Access Programs
Clinical Trial Services
Patient Site Solutions
Clinical Trial Supply
Market Access and Commercialization
 
Data Privacy Notice:
WEP Clinical is committed to protecting your personal information throughout the recruitment process. By applying, you acknowledge that your personal data will be processed in accordance with our Privacy Policy and Job Applicant Privacy Notice.
 
Privacy Policy: https://www.wepclinical.com/privacy-policy/
Job Applicant Privacy Notice: https://www.wepclinical.com/Job-Applicant-Privacy-Notice/
 
How to Apply:
To be considered for this role, please submit your resume through the WEP Clinical Careers Portal or by using LinkedIn's Easy Apply option. Please ensure your resume is in English. 
 
Important Note:
To streamline our hiring process, we use an Upwage AI screener. If you receive a link from Upwage, it is a legitimate part of our application process and helps ensure every candidate is reviewed consistently. If you are selected to move forward after the screener, a member of our team will contact you directly from an @wepclinical.com email address to guide you through the next steps of the interview process. Please ensure you apply only through our official careers page (https://www.wepclinical.com/careers/) or our verified LinkedIn page. 

For Your Safety, Please Note:

We will never communicate with you via Microsoft Teams or text message.

We will never ask for your bank account information at any stage of recruitment. 

 
WEP Clinical is a smoke-free, drug-free, and alcohol-free work environment.
 
WEP Clinical is an equal-opportunity employer. WEP Clinical does not unlawfully discriminate against employees or applicants for employment based on an individual's race, colour, religion, creed, sex, sexual orientation, gender identity or expression, national origin, genetic information, age, disability, marital status, veteran status or any other status protected by applicable law. This policy applies to all terms, conditions, and privileges of employment, including recruitment, hiring, placement, compensation, promotion, discipline, and termination. WEP Clinical will make reasonable accommodation for qualified individuals with known disabilities, in accordance with applicable law.
 
#LI-fulltime 
#LI-remote 
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
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