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Clinical Systems Engineer Jobs in California (NOW HIRING)

Nudge

Quality Systems Engineer

San Francisco, CA · On-site

About the role As a quality systems engineer at Nudge, you will: * Ensure that new and existing ... Familiarity with Good Clinical Practice (GCP) and human factors * Familiarity with the FDA QMSR ...

nudge

Quality Systems Engineer

San Francisco, CA · On-site

About the role As a quality systems engineer at Nudge, you will: * Ensure that new and existing ... Familiarity with Good Clinical Practice (GCP) and human factors * Familiarity with the FDA QMSR ...

Diality

Senior Systems Engineer

Irvine, CA · On-site

$120K - $133K/yr

... non-clinical users. The Moda-flx Hemodialysis system combines flow rate capabilities of ... As a Senior Systems Engineer, you will leverage your extensive expertise to drive the design ...

Cytek Biosciences Inc

Sr. Systems Engineer

Fremont, CA · On-site

$126K - $185K/yr

Cytek is seeking a Senior Systems Engineer to support the development, integration, verification ... Translate customer, clinical, manufacturing, service, and regulatory needs into clear and testable ...

Cytek Biosciences, Inc.

Sr. Systems Engineer

Fremont, CA · On-site

$123K - $169K/yr

Cytek is seeking a Senior Systems Engineer to support the development, integration, verification ... Translate customer, clinical, manufacturing, service, and regulatory needs into clear and testable ...

Stryker

Senior Video Systems Engineer

San Jose, CA · Hybrid

$101K - $168K/yr

Translate clinical, user, business, and regulatory needs into clear system-level requirements ... Bachelor's degree in engineering, systems engineering, or a related field, with 2+ years of ...

Stryker

Senior Video Systems Engineer

San Jose, CA · On-site

$101K - $168K/yr

Translate clinical, user, business, and regulatory needs into clear system-level requirements ... Bachelor's degree in engineering, systems engineering, or a related field, with 2+ years of ...

B Capital

Principal Systems Engineer

Santa Clarita, CA · On-site

$106.80 - $202.90/hr

Define and analyze system requirements, clinical workflows, and input/output processes by using systems engineering methods and techniques * Apply critical thinking to solve systems integration ...

Cypress HCM

Control Systems Engineer

Irvine, CA

$200K - $250K/yr

Lead research and feasibility of new concepts, conduct animal studies and clinical data collection ... control engineering and system dynamics. * Expert knowledge in signal processing, system ...

Dexcom, Inc.

Senior Staff Systems Engineer

San Diego, CA · On-site

$110K - $151K/yr

You will act as the technical anchor for software-centric systems, partnering closely with Product Management, Software Engineering, Clinical, Regulatory, Quality, Cybersecurity, Data Platform, and ...

Dexcom

Senior Staff Systems Engineer

San Diego, CA · On-site

$110K - $151K/yr

You will act as the technical anchor for software-centric systems, partnering closely with Product Management, Software Engineering, Clinical, Regulatory, Quality, Cybersecurity, Data Platform, and ...

Werfen

Systems Engineer - San Diego

San Diego, CA

$150K - $180K/yr

The system engineer may have interactions with customers, clinicians, third-party vendors, manufacturers, and others. This role is fully onsite at our Scripps Ranch location. DUTIES/RESPONSIBILITIES:

Werfen

Systems Engineer - San Diego

San Diego, CA

$150K - $180K/yr

The system engineer may have interactions with customers, clinicians, third-party vendors, manufacturers, and others.This role is fully onsite at our Scripps Ranch location. Responsibilities DUTIES ...

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Showing results 21-40

All JobsClinical Systems Engineer JobsClinical Systems Engineer Jobs in California

Clinical Systems Engineer information

See California salary details

$40K

$92.5K

$134.2K

How much do clinical systems engineer jobs pay per year?

As of Aug 11, 2026, the average yearly pay for clinical systems engineer in California is $92,473.00, according to ZipRecruiter salary data. Most workers in this role earn between $69,100.00 and $108,100.00 per year, depending on experience, location, and employer.

What does a clinical systems engineer do?

A Clinical Systems Engineer is responsible for managing and optimizing healthcare technology systems, ensuring they function safely and efficiently. They work with medical devices, electronic health record (EHR) systems, and IT infrastructure to improve clinical workflows. Their role involves troubleshooting, integrating new technologies, ensuring compliance with regulations, and collaborating with clinicians and IT teams to enhance patient care.

What are the key skills and qualifications needed to thrive as a clinical systems engineer?

To excel as a Clinical Systems Engineer, you need a strong background in biomedical engineering, information systems, and familiarity with healthcare regulations, usually supported by a relevant degree. Experience with medical device integration, clinical IT systems (such as PACS, EHRs), and certifications like CCE or CBET are highly valuable. Strong problem-solving, communication skills, and the ability to train or support clinical staff set candidates apart in this role. These abilities are crucial for ensuring that healthcare technology is implemented safely, efficiently, and in full compliance with regulatory standards.

What are popular job titles related to Clinical Systems Engineer jobs in California? For Clinical Systems Engineer jobs in California, the most frequently searched job titles are:
What job categories do people searching Clinical Systems Engineer jobs in California look for? The top searched job categories for Clinical Systems Engineer jobs in California are:
Clinical Systems Engineer jobs near you
Infographic showing various Clinical Systems Engineer job openings in California as of August 2026, with employment types broken down into 86% Full Time, 4% Part Time, and 10% Contract. Highlights an 88% In-person, 8% Hybrid, and 4% Remote job distribution, with an average salary of $92,473 per year, or $44.5 per hour.

Quality Systems Engineer

Nudge

San Francisco, CA • On-site

Full-time

Re-posted 8 days ago

Job description

About Nudge

At Nudge, our mission is to develop the best technology for interfacing with the brain to improve people's lives. We're starting with an approach that we believe can help the most people the fastest, and also allow us to learn as much about the brain as possible: developing a non-invasive, ultrasound-based device that can stimulate and image the brain at high resolution and depth. This is a vertically integrated effort building cutting-edge hardware, software, and research capabilities to create products that can benefit millions — and eventually billions — of people.

To succeed, we need to assemble world-class teams across everything we do. We hire people who are exceptional at their craft, believe hard things are worth doing, and execute relentlessly — people who expect the highest levels of both rigor and integrity from each other.

About the role

As a quality systems engineer at Nudge, you will:

  • Ensure that new and existing product designs and processes meet all internal and regulatory requirements with respect to safety and performance

  • Partner in new product development by leading quality critical discussions, influencing key decisions, and driving necessary process changes across design controls, investigational studies, and clinical trials

  • Effectively manage multiple tasks and drive execution of change orders

  • Initiate and/or support corrective action and preventive action (CAPAs) and non-conformances, leading investigations and implementing mitigations

  • Represent and cultivate a culture of quality by working with interdisciplinary teams to set expectations, identify gaps, and meet a high internal bar for rigor

About you

We are looking for quality systems engineers with at least 2 years of industry experience. Regardless of career level, you should have:

  • Experience with design controls, product/process validation, and risk management

  • A degree in an engineering or scientific discipline (e.g., biomedical engineering, electrical engineering, neuroscience) or equivalent hands-on experience

  • Familiarity with Good Clinical Practice (GCP) and human factors

  • Familiarity with the FDA QMSR, ISO 13485, and ISO 14971

  • Experience conducting risk management activities using tools such as failure mode and effects analysis (FMEA)

  • Strong technical writing skills

  • High integrity and strong professional judgement