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Clinical Science Manager Jobs in California (NOW HIRING)

Olema Oncology

Director, Clinical Science

San Francisco, CA · On-site

$94K - $128K/yr

... Management, Biostatistics, Clinical Pharmacology, Regulatory and Program Management, in the ... Attending scientific meetings pertinent to clinical science activities And will also include:

Janux Therapeutics

Director, Clinical Science

San Diego, CA · On-site +1

$236K - $255K/yr

Maintain scientific and clinical knowledge in the specific therapeutic and disease areas of ... Strong project management skills In addition to a competitive base salary ranging from $236,000 to ...

Travere Therapeutics

Director, Clinical Science

San Diego, CA · On-site

$86K - $117K/yr

The Director, Clinical Science, will provide management and support for Travere's on-going and future nephrology development and life-cycle activities for clinical programs. The position will work ...

Travere

Director, Clinical Science

San Diego, CA · On-site +1

$84K - $115K/yr

The Director, Clinical Science, will provide management and support for Travere's on-going and future nephrology development and life-cycle activities for clinical programs. The position will work ...

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Clinical Science Manager information

See California salary details

$42.9K

$81.3K

$138.2K

How much do clinical science manager jobs pay per year?

As of Aug 26, 2026, the average yearly pay for clinical science manager in California is $81,272.00, according to ZipRecruiter salary data. Most workers in this role earn between $64,100.00 and $88,300.00 per year, depending on experience, location, and employer.

What is a clinical science manager?

Clinical Science Managers are professionals who oversee and coordinate clinical research projects, often within the pharmaceutical, biotechnology, or medical device industries. They are responsible for managing clinical trials, ensuring regulatory compliance, and collaborating with cross-functional teams such as clinical operations, regulatory affairs, and medical affairs. Their role involves protocol development, data analysis, and ensuring the safety and efficacy of investigational products. Clinical Science Managers also play a critical part in interpreting study results and presenting findings to stakeholders. They typically have advanced degrees in life sciences and significant experience in clinical research.

What are the key skills and qualifications needed to thrive as a clinical science manager?

To thrive as a Clinical Science Manager, you need a solid background in clinical research, life sciences, and project management, typically supported by an advanced degree (e.g., PharmD, PhD, or MD) and industry experience. Familiarity with clinical trial management systems, regulatory compliance tools, and data analysis platforms is crucial. Strong leadership, strategic thinking, and effective communication skills help you manage cross-functional teams and build relationships with stakeholders. These competencies ensure the successful design, execution, and oversight of clinical studies, ultimately advancing scientific and business goals.

How does a clinical science manager typically collaborate with cross-functional teams during clinical trial development?

Clinical Science Managers play a key role in bridging scientific objectives with operational execution by working closely with clinical operations, regulatory affairs, data management, and medical affairs teams. They often lead the development of clinical protocols and ensure scientific integrity throughout the study, facilitating regular meetings and communication to align project goals and timelines. Their collaborative efforts help anticipate and resolve challenges, streamline processes, and ensure that trials meet regulatory requirements and scientific standards.

What is the difference between Clinical Science Manager vs Clinical Research Associate?

AspectClinical Science ManagerClinical Research Associate
CredentialsTypically requires advanced degrees (e.g., Master’s or PhD) and industry experienceUsually holds a bachelor’s degree in life sciences or related field
Work EnvironmentLeads teams, manages projects, and oversees clinical studiesMonitors clinical trials at sites, ensures protocol compliance
Employer & Industry UsagePharmaceutical, biotech, and medical device companiesContract research organizations, pharmaceutical companies
Search & Comparison IntentUnderstanding managerial roles in clinical scienceFocus on trial monitoring and site management

The Clinical Science Manager typically oversees clinical projects and manages teams, requiring advanced credentials. In contrast, the Clinical Research Associate focuses on monitoring clinical trials at sites. Both roles are essential in the clinical research process but differ in responsibilities and experience levels.

What are popular job titles related to Clinical Science Manager jobs in California?

For Clinical Science Manager jobs in California, the most frequently searched job titles are:

What job categories do people searching Clinical Science Manager jobs in California look for?

The top searched job categories for Clinical Science Manager jobs in California are:

What cities in California are hiring for Clinical Science Manager jobs?

Cities in California with the most Clinical Science Manager job openings:

Clinical Science Manager jobs near you
Infographic showing various Clinical Science Manager job openings in California as of August 2026, with employment types broken down into 88% Full Time, and 12% Contract. Highlights an 81% In-person, 5% Hybrid, and 14% Remote job distribution, with an average salary of $81,272 per year, or $39.1 per hour.

Director, Clinical Science

South San Francisco, CA • On-site

Electra Therapeutics, Inc.
11 - 50 employees
Learn more about Electra Therapeutics, Inc.external

$96K - $131K/yr

Full-time

Re-posted 19 days ago

Job description

SUMMARY OF POSITION: Electra Therapeutics, based in South San Francisco, California, is a clinical stage biotechnology company developing therapies that target signal regulatory proteins (SIRP) for the treatment of immunological diseases and cancer.

The Director of Clinical Science will report to the Senior Director of Clinical Development and play a critical role in supporting clinical programs, with a strong emphasis on clinical data review, data analysis, and interpretation to ensure the quality, accuracy, and integrity of the studies. The ideal candidate will bring hands-on experience in clinical science with familiarity in data management process to partner effectively with cross-functional teams as well as a background in leading and conducting natural history studies. This role requires someone who is highly detail-oriented and thrives on diving deep into complex datasets, bringing both rigor and curiosity to uncover insights that drive program success.

KEY RESPONSIBILITIES: 

  • Provide scientific leadership for clinical programs including study, data interpretation, and reporting.
  • Lead and participate in clinical data review and analysis to support data cleaning, patient safety review, and data integrity throughout the study lifecycle.
  • Partner with clinical development, clinical operations, and data management to ensure high-quality data delivery.
  • Contribute to data interpretation that informs clinical trial results, regulatory submissions, and publications.
  • Support preparation of manuscripts, abstracts, posters, and presentations by assembling data outputs and ensuring scientific accuracy.
  • Provide scientific and clinical input into study design, endpoint selection, and statistical analysis planning.
  • Participate in cross-functional team meetings and act as a clinical science point of contact for internal and external stakeholders.
  • Contribute to the development and review of key study documents (e.g., protocols, CRFs, data review plans, study reports, regulatory submissions).
  • Support data management activities including database design input, eCRF development, and oversight of data flow.

QUALIFICATIONS:

  • Advanced degree in life sciences (PhD, PharmD, M.S., or equivalent preferred).
  • 7+ years of experience in clinical science and/or epidemiology within the biotech or pharmaceutical industry
  • Demonstrated expertise in data review, analysis, and interpretation.
  • Strong understanding of clinical trial methodology, Good Clinical Practice (GCP), and regulatory requirements.
  • Familiarity with data management concepts, tools, and processes (e.g., EDC, eCRF design, query management), specifically in Medidata RAVE.
  • Experience with natural history studies, epidemiology studies, and real-world evidence (RWE), in oncology and/or rare diseases
  • Excellent organizational skills with the ability to manage multiple priorities in a fast-paced environment.
  • Strong written and verbal communication skills, with proven ability to collaborate across functions.

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