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Clinical Research Site Manager Jobs in Riverside, CA

Clinical Development & Research - Non-MD Job Category: Scientific/Technology All Job Posting ... May serve as the primary contact for clinical trial sites (e.g. site management); * Develops ...

Clinical Development & Research - Non-MD Job Category: Scientific/Technology All Job Posting ... May serve as the primary contact for clinical trial sites (e.g. site management); * Develops ...

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Clinical Research Site Manager information

See Riverside, CA salary details

$51.1K

$112K

$197.2K

How much do clinical research site manager jobs pay per year?

As of Sep 5, 2026, the average yearly pay for clinical research site manager in Riverside, CA is $111,980.00, according to ZipRecruiter salary data. Most workers in this role earn between $84,500.00 and $127,800.00 per year, depending on experience, location, and employer.

What does a clinical research site manager do?

A Clinical Research Site Manager is responsible for overseeing the daily operations of clinical trials conducted at a research site. They ensure that studies are conducted in compliance with regulatory guidelines, manage site staff, coordinate with sponsors and monitors, and maintain accurate documentation. Their work is crucial for ensuring patient safety, data integrity, and the successful completion of clinical research studies.

What are the key skills and qualifications needed to thrive as a clinical research site manager?

To thrive as a Clinical Research Site Manager, you need a solid background in clinical research, regulatory compliance, and project management, often supported by a bachelor’s or master’s degree in a health-related field. Familiarity with clinical trial management systems (CTMS), Good Clinical Practice (GCP) guidelines, and regulatory documentation is crucial. Strong leadership, organizational, and communication skills help you coordinate teams, manage timelines, and foster productive sponsor relationships. These skills and qualities are vital for ensuring clinical trial integrity, regulatory adherence, and successful study outcomes.

What are some common challenges faced by clinical research site managers, and how can they be addressed?

Clinical Research Site Managers often encounter challenges such as balancing multiple studies simultaneously, ensuring regulatory compliance, and maintaining participant recruitment targets. Managing communication between sponsors, investigators, and clinical staff can also be complex, especially when timelines are tight. These challenges are typically addressed by implementing strong organizational systems, fostering open communication among team members, and staying updated with regulatory changes through ongoing training.

What is the difference between Clinical Research Site Manager vs Clinical Research Coordinator?

AspectClinical Research Site ManagerClinical Research Coordinator
CredentialsBachelor's degree; often experience in clinical settingsBachelor's degree; relevant certifications often preferred
Work EnvironmentOversees entire research site operationsAssists with patient recruitment, data collection, and study procedures
Employer & Industry UsageResearch institutions, pharmaceutical companies, CROsHospitals, clinics, research sites

The Clinical Research Site Manager typically oversees the entire research site, managing staff and operations, while the Clinical Research Coordinator focuses on day-to-day study activities and participant coordination. Both roles require relevant experience and certifications, but the Site Manager has broader responsibilities in leadership and site management.

What are popular job titles related to Clinical Research Site Manager jobs in Riverside, CA?

For Clinical Research Site Manager jobs in Riverside, CA, the most frequently searched job titles are:

What job categories do people searching Clinical Research Site Manager jobs in Riverside, CA look for?

The top searched job categories for Clinical Research Site Manager jobs in Riverside, CA are:

What cities near Riverside, CA are hiring for Clinical Research Site Manager jobs?

Cities near Riverside, CA with the most Clinical Research Site Manager job openings:

Infographic showing various Clinical Research Site Manager job openings in Riverside, CA as of August 2026, with employment types broken down into 86% Full Time, 13% Part Time, and 1% Contract. Highlights an 84% Physical, 2% Hybrid, and 14% Remote job distribution, with an average salary of $111,980 per year, or $53.8 per hour.

Clinical Research Site Manager

Headlands Research

Riverside, CA • On-site

Full-time

PTO

Re-posted 2 days ago


Job description

The Role

The Site Manager performs clinical research activities as a Clinical Research Coordinator while also serving as Manager of the site operations. The Site Manager owns meeting or exceeding financial targets, KPIs, and patient enrollment, as well as champions screening, patient retention, and partnering with other Headlands centralized departments or sites.

Position Type:  Full-time

Location:  Onsite in Riverside, CA

Responsibilities:

  • Strategic and Operational Management
    • Evaluates overall performance of the Site and recommends and implements processes and plans for improvement.
    • Responsible for maintaining a site calendar to ensure adequate enrollment for studies and coordination of employee PTO.
  • Staff Development and Management
    • Fosters a culture of excellence, teamwork, and innovation among site staff
    • Hires, trains, and mentors site staff, including Clinical Research Coordinators, Research Assistants, Administrative Assistants, Registered Nurses, support personnel, etc.
    • Partners with Human Resources and Management when hiring new employees for the site by reviewing candidate credentials, conducting interviews, and giving input about potential new hires
    • Supervises performance of other Clinical Research Coordinators, Research Assistants, and support staff at the Site
  • Quality Assurance & Compliance
    • Maintains up-to-date knowledge of all relevant regulatory guidelines and requirements
    • Ensures the site's compliance with FDA, ICH, and local regulatory agency regulations
  • Clinical Research Coordination
    • In addition to assuming management responsibilities as a Site Manager, this individual performs the duties of a Clinical Research Coordinator
    • Protects the rights, safety, and welfare of human subjects, follows Good Clinical Practice, and works cooperatively with others
    • Monitors study activities to ensure compliance with study protocols, with site policies, and with applicable federal, state, and local regulations
    • Oversee the planning, initiation, and execution of clinical trials at the site
    • Maintains required records of study activity including case report forms, drug dispensation records, and regulatory forms
    • Manages and optimizes patient recruitment and retention efforts
    • Assesses eligibility of potential subjects through methods such as screening interviews, reviews of medical records, and discussions with physicians and other healthcare professionals
    • Addresses any patient concerns or issues promptly and professionally
  • Documentation and Reporting
    • Documents findings and events in the CTMS platform and in other binders and platforms as directed
    • Reviews proposed study protocols to evaluate factors such as sample collection processes, data management plans, and potential subject risks
  • Performs other duties as assigned, including duties routinely performed by the Company's Research Assistants

 

Requirements:

  • 5+ years of experience as a delegated Clinical Research Coordinator on multiple phase 2-4 clinical research trials, simultaneously
  • Proficiency in FDA regulations governing clinical trials
  • Strong supervisory skills to lead research staff effectively
  • Ability to collect and manage research data accurately
  • Familiarity with documentation review processes in clinical research
  • Knowledge of medical terminology relevant to clinical trials management
  • IATA (dangerous goods handling)
  • GCP (Good Clinical Practice)
  • Strong communication skills with all members of the team.

Preferred Qualifications:

  • Bachelor's degree
  • Capability to perform phlebotomy procedures
  • CCRC or CCRP certified