Clinical Research Associate Remote Jobs in Missouri

LOCATION: U.S. locations - remote/hybrid (8 days a month in the office). Candidates within commuting distance of a Wolters Kluwer office will be considered for hybrid employment (within 50 miles of an office). Candidates not within commuting distances will be considered for remote employment. Please see eligible locations on the posting.

OVERVIEW

Wolters Kluwer, UpToDate and Lexidrug is seeking experienced clinicians to join our team as Clinical Artificial Intelligence (AI) Strategists. This role is central to advancing the clinical reasoning framework that underpins our next generation of trustworthy, clinically intelligent AI systems. You will work cross-functionally to evolve and operationalize this framework across AI architecture, system validation, and clinical workflows, ensuring outputs remain clinically sound and faithful to our trusted content.

You will help shape the future of clinical decision support by combining deep expertise in clinical reasoning with strong technical fluency and communication skills. Working across Clinical AI, Product, Engineering, Editorial, and Design, you will translate clinical thinking into scalable AI capabilities that meaningfully support patient care.

RESPONSIBILITIES

Clinical AI Strategy & Development (80%-100%)

• Serve as the clinical lead on our clinical reasoning framework, guiding its continued advancement and application across AI initiatives.
• Partner with Product, Engineering, Editorial, and AI teams to translate clinical reasoning into scalable AI system capabilities.
• Define and maintain clinical indices, decision pathways, reasoning frameworks, and evaluation approaches that reflect real-world clinical decision making across specialties.
• Contribute to clinical validation platform development, including development of clinical test sets, reasoning benchmarks, red teaming protocols, safety evaluations, and ongoing expert review to ensure outputs remain clinically faithful, useful, and meaningful.
• Translate clinician and customer feedback into improvements in AI system behavior and the continued evolution of the clinical reasoning framework.
• Serve as a clinical liaison between the Clinical AI team and traditional editorial operations, helping align clinical standards, workflows, and content strategy.
• Communicate effectively across clinical, technical, and business teams, translating complex clinical concepts into practical system requirements and technical concepts into clinically meaningful guidance.
• Represent Wolters Kluwer externally through white papers, conference presentations, and thought leadership.

Clinical Practice (optional - up to 20%)

Clinicians may allocate time to maintain active clinical practice, ensuring continued relevance and real-world insight; existing clinical stipend for physician editors will continue to apply.

QUALIFICATIONS

Education

• MD, DO, PharmD, Advanced Practice Provider, or equivalent clinical degree: M.D. strongly preferred

Experience

• Minimum 5 years of clinical practice, with demonstrated depth in patient care and breadth across domains such as hospital administration, patient safety, quality improvement, clinical research, medical education, clinical informatics, or publishing.
• Demonstrated expertise in clinical reasoning as a discipline, including diagnostic reasoning, therapeutic decision making, uncertainty management, and evidence-based clinical decision making, as evidenced by teaching, publication, research, curriculum development, or related scholarly work.
• Active clinical practice preferred; board certification preferred.
• Valid medical license in at least one U.S. state preferred.
• Strong understanding of modern AI technologies, including generative AI and large language models, with the ability to apply clinical expertise to AI development and evaluation. Experience with AI, informatics, machine learning, or digital health innovation is strongly preferred.
• Excellent written, verbal, and technical communication skills, with the ability to translate clinical reasoning into system logic and communicate effectively with both clinical and technical audiences.
• Experience working across agile, cross-functional environments, with the ability to build alignment and strong partnerships across clinical, engineering, product, and editorial teams.
• Comfort with ambiguity and rapid iteration; ability to adapt quickly as AI technologies and organizational priorities evolve.
• Strategic mindset with the ability to contribute to Clinical AI strategy and influence the evolution of clinical AI capabilities.
• Leadership experience guiding complex initiatives or multidisciplinary teams is strongly preferred.
• Experience supporting senior leaders through strategic analysis, written briefings, and cross-functional initiatives is preferred.

TRAVEL: Approximately one week every six weeks for team meetings and collaborative planning.

#LI-Remote

To maintain a fair and genuine hiring process, we kindly ask that all candidates participate in interviews without the assistance of AI tools or external prompts. Our interview process is designed to assess your individual skills, experiences, and communication style. We value authenticity and want to ensure we're getting to know you-not a digital assistant. To help maintain this integrity, we ask to remove virtual backgrounds and include in-person interviews in our hiring process. Please note that use of AI-generated responses or third-party support during interviews will be grounds for disqualification from the recruitment process.

Applicants may be required to appear onsite at a Wolters Kluwer office as part of the recruitment process.

Compensation:

Compensation range listed is based on primary location of the position. Actual base salary offer is influenced by a wide array of factors including but not limited to skills, experience and actual hiring location. Your recruiter can share more information about the specific offer for the job location during the hiring process.

Wolters Kluwer offers a wide variety of competitive benefits and programs to help meet your needs and balance your work and personal life, including but not limited to: Medical, Dental, & Vision Plans, 401(k), FSA/HSA, Commuter Benefits, Tuition Assistance Plan, Vacation and Sick Time, and Paid Parental Leave. Full details of our benefits are available upon request.