ZipRecruiter

Log In

1

Clinical Operation Manager Jobs in Delaware (NOW HIRING)

Phenom People

Clinical Manager

Smyrna, DE · On-site

Ensure provision of quality patient care while maintaining cost-effective clinical operations in ... Manages the tactical execution of short- and long-term objectives through the coordination of ...

ICON

Biospecimen Operations Manager

Wilmington, DE · On-site

Biospecimen Operations Manager ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As a values ...

Icon plc

Biospecimen Operations Manager

Wilmington, DE · Hybrid

Biospecimen Operations Manager ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As a values ...

next page

Showing results 1-20

All JobsClinical Operation JobsClinical Operation Manager JobsClinical Operation Manager Jobs in Delaware

Clinical Operation Manager information

See Delaware salary details

$35K

$98.1K

$186.7K

How much do clinical operation manager jobs pay per year?

As of Aug 14, 2026, the average yearly pay for clinical operation manager in Delaware is $98,123.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,600.00 and $113,600.00 per year, depending on experience, location, and employer.

What are some common challenges clinical operation managers face when coordinating multi-site clinical trials?

Clinical Operation Managers often encounter challenges such as ensuring consistent protocol adherence across all sites, managing communication among geographically dispersed teams, and maintaining timelines despite unexpected delays. They must also address regulatory differences between sites and troubleshoot issues related to patient recruitment and data collection. Success in this role requires strong organizational skills, adaptability, and effective collaboration with investigators, coordinators, and regulatory personnel.

What are the key skills and qualifications needed to thrive as a clinical operation manager?

To thrive as a Clinical Operation Manager, you need expertise in clinical project management, regulatory compliance, and a background in healthcare or life sciences, often supported by a relevant degree. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications such as PMP or Six Sigma are commonly required. Strong leadership, problem-solving abilities, and excellent communication skills set top performers apart in this role. These competencies are essential for ensuring efficient clinical operations, maintaining regulatory standards, and leading teams to deliver successful trial outcomes.

What is a clinical operation manager?

Clinical Operation Managers are professionals responsible for overseeing the daily operations of clinical research sites, medical facilities, or departments. They ensure that clinical trials or healthcare services are conducted efficiently, comply with regulations, and meet quality standards. Their duties often include supervising staff, managing budgets, implementing policies, and coordinating between various teams. Clinical Operation Managers play a crucial role in ensuring that patient care and research activities run smoothly and effectively.

What is the difference between Clinical Operation Manager vs Clinical Research Coordinator?

AspectClinical Operation ManagerClinical Research Coordinator
CredentialsBachelor's degree in health sciences, life sciences, or related field; often with project management certificationsBachelor's degree in health sciences, nursing, or related field; often with research-specific training
Work EnvironmentOversees multiple clinical trials, manages teams, and ensures compliance at a departmental levelCoordinates daily activities of clinical trials, interacts directly with participants and investigators
Employer & IndustryPharmaceutical companies, biotech firms, hospitals, research institutionsResearch sites, hospitals, academic institutions, contract research organizations

The Clinical Operation Manager focuses on overseeing clinical trial operations, managing teams, and ensuring compliance across projects. In contrast, the Clinical Research Coordinator handles the day-to-day activities of specific trials, working closely with participants and investigators. Both roles require relevant healthcare or science credentials, but their scope and responsibilities differ significantly.

What are popular job titles related to Clinical Operation Manager jobs in Delaware?

For Clinical Operation Manager jobs in Delaware, the most frequently searched job titles are:

What job categories do people searching Clinical Operation Manager jobs in Delaware look for?

The top searched job categories for Clinical Operation Manager jobs in Delaware are:

What cities in Delaware are hiring for Clinical Operation Manager jobs?

Cities in Delaware with the most Clinical Operation Manager job openings:

Clinical Operation Manager jobs near you
Infographic showing various Clinical Operation Manager job openings in Delaware as of August 2026, with employment types broken down into 1% As Needed, 83% Full Time, 14% Part Time, and 2% Contract. Highlights an 93% Physical, 3% Hybrid, and 4% Remote job distribution, with an average salary of $98,123 per year, or $47.2 per hour.

Director, Clinical Operations

Incyte Corporation

Wilmington, DE • On-site

Full-time

This job post has expired 2 days ago. Applications are no longer accepted.

Job description

Overview
A global biopharmaceutical company on a mission to Solve On, Incyte follows science to find solutions for patients with unmet medical needs. Through the discovery, development, and commercialization of proprietary therapeutics, Incyte has established a portfolio of first-in-class medicines for patients and a strong pipeline of products in Hematology, Oncology and Inflammation and Autoimmunity
Headquartered in Wilmington, Delaware, Incyte has operations in North America, Europe, and Asia.
Job Summary (Primary function)
The Director, Clinical Operations provides strategic, operational, and people leadership for global Phase I-III clinical trials, including first-in-human and pivotal studies. This role oversees end-to-end clinical trial execution, ensures compliance with FDA/EMEA regulations and ICH-GCP, manages CROs and vendors, and partners cross-functionally to deliver high-quality clinical programs aligned with corporate objectives. The Director also leads Clinical Operations staff, drives operational excellence, and contributes to program-level planning across Incyte's Hematology, Oncology, and Inflammation/Autoimmunity portfolio.
Essential Functions of the Job (Key responsibilities)
  • Provide strategic operational leadership for assigned clinical programs, including feasibility, resource forecasting, and long-range planning.
  • Contribute to program-level strategy, timelines, budgets, and operational deliverables in alignment with corporate goals.
  • Ensure harmonized operational plans and high-quality data across global trials.
  • Lead end-to-end planning, implementation, and management of global Phase I-III trials, including first-in-human studies.
  • Oversee day-to-day clinical operations to ensure adherence to timelines, budgets, SOPs, ICH-GCP, and country-specific regulations.
  • Manage investigational product accountability and reconciliation processes.
  • Support preparation of safety updates, interim analyses, and final clinical study reports; resolve data discrepancies.
  • Partner closely with Clinical Development, Regulatory, Biometrics, Supply Chain, and other internal teams to achieve study objectives.
  • Lead and/or participate in cross-functional study team meetings, ensuring alignment and timely decision-making.
  • Collaborate with senior management to determine clinical supply requirements and operational strategy.
  • Select, negotiate, and manage CROs and external vendors (central labs, EDC providers, patient recruitment partners, etc.).
  • Develop RFPs, conduct cost analyses, and ensure vendor performance meets quality, timeline, and budget expectations.
  • Provide strategic oversight of CRO governance and issue resolution.
  • Contribute to the development and review of protocols, amendments, ICFs, CRFs, study guides, operational plans, and charters.
  • Participate in preparation of INDs, Investigator Brochures, regulatory briefing documents, and other clinical submissions.
  • Ensure operational feasibility and high-quality clinical data across studies.
  • Build and maintain strong relationships with investigator sites, KOLs, patient advocacy groups, and referral networks.
  • Support site engagement strategies to ensure enrollment targets and study goals are met.
  • Recruit, manage, and mentor Clinical Trial Managers, Clinical Trial Specialists, and other direct reports.
  • Provide clear objectives, ongoing coaching, and performance evaluations.
  • Foster a culture of engagement, accountability, and collaboration.
  • Provide regular updates and status reports to senior leadership.

Qualifications (Minimal acceptable level of education, work experience, and competency)
  • Bachelor's degree in Life Sciences or related field required.
  • 10+ years of clinical operations experience in biopharma or biotech.
  • Minimum 5 years of direct clinical study management experience.
  • Extensive experience managing global Phase I-III trials; first-in-human experience strongly preferred.
  • Oncology experience preferred; rare disease experience desirable.
  • Global clinical development experience preferred.
  • Strong knowledge of FDA/EMEA regulations, ICH-GCP, and clinical trial methodology.
  • Proven ability to manage CROs and external vendors.
  • Experience with clinical systems (EDC, CTMS, eTMF) and operational documentation.
  • Demonstrated ability to manage budgets, timelines, and complex operational plans.
  • Proven ability to lead and develop high-performing teams.
  • Strong organizational, time-management, and problem-solving skills.
  • Excellent written and verbal communication skills.
  • Thrives in a collaborative, fast-paced, high-energy environment.
  • Ability to travel domestically and internationally (up to 30%).

Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.
Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.
We Respect Your Privacy
Learn more at: http://www.incyte.com/privacy-policy
The Incyte hiring organization processes your personal data to manage your job application in order to enter into an employment relationship with you if you are the successful candidate.
During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job. You can learn more about this process here.
You may have the right to access, delete, restrict, edit, move, or object to the use of your personal data. You may also have a right to report concerns to the authority responsible for data privacy in the country where the position is based or where you live or work.
You can learn more about Incyte's data protection practices here. By accessing this link you can learn about the types of personal data we collect, how we use it, whether collection and processing is optional, sources of the personal data we process, how it is shared, where it is stored or transferred to, how long we keep it, and contact information for Incyte, Incyte's data protection officer, and your supervisory authority (if applicable).
Please contact privacy@incyte.com if you have any questions or concerns or would like to exercise your rights.
VWD

Apply