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Clinical Monitoring Jobs in Missouri (NOW HIRING)

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Clinical Monitoring information

See Missouri salary details

$11

$38

$65

How much do clinical monitoring jobs pay per hour?

As of Aug 9, 2026, the average hourly pay for clinical monitoring in Missouri is $38.58, according to ZipRecruiter salary data. Most workers in this role earn between $27.07 and $49.38 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in clinical monitoring, and why are they important?

To thrive in Clinical Monitoring, you need a solid background in life sciences or nursing, strong knowledge of clinical trial protocols, and often a relevant degree such as a BS in a scientific field. Familiarity with electronic data capture (EDC) systems, Good Clinical Practice (GCP) guidelines, and certifications like ACRP or SOCRA are highly valued. Exceptional attention to detail, strong organizational skills, and effective communication are crucial soft skills for managing trial sites and ensuring compliance. These competencies are vital for ensuring data integrity, regulatory adherence, and the smooth progress of clinical trials.

What is the difference between Clinical Monitoring vs Clinical Data Management?

AspectClinical MonitoringClinical Data Management
Primary RoleOversees site activities, ensures protocol adherence, monitors patient safetyCollects, validates, and manages clinical trial data
Required CredentialsTypically a degree in life sciences, nursing, or related field; often requires monitoring certificationsDegree in life sciences, biostatistics, or related; data management certifications beneficial
Work EnvironmentOn-site at clinical trial sites or remotely, interacting with site staffPrimarily office-based, working with electronic data capture systems
Industry UsageCommonly used in clinical trial phases, especially during site visitsUsed throughout the trial for data collection, cleaning, and analysis

Clinical Monitoring focuses on overseeing clinical trial sites and ensuring compliance, while Clinical Data Management handles the collection and validation of trial data. Both roles are essential in clinical research, often working closely but with distinct responsibilities.

What is clinical monitoring?

Clinical monitoring is the process of overseeing clinical trials to ensure they are conducted, recorded, and reported in accordance with the protocol, standard operating procedures, Good Clinical Practice (GCP), and regulatory requirements. Clinical monitors, often called Clinical Research Associates (CRAs), are responsible for checking the progress of a clinical trial at research sites, verifying data accuracy, ensuring participant safety, and ensuring compliance with regulations. Their work is essential in maintaining the integrity of clinical data and the safety of trial participants.

What are some common challenges faced by professionals in clinical monitoring, and how can they be addressed?

Clinical Monitoring professionals often encounter challenges such as managing multiple study sites, ensuring protocol compliance, and maintaining clear communication with site staff. Navigating regulatory requirements and handling unexpected issues, like protocol deviations or data discrepancies, can also be demanding. To address these, strong organizational skills, proactive communication, and thorough documentation are essential. Building collaborative relationships with site personnel and staying updated on regulatory guidelines can help ensure smoother study progress and data integrity.
What cities in Missouri are hiring for Clinical Monitoring jobs? Cities in Missouri with the most Clinical Monitoring job openings:
Infographic showing various Clinical Monitoring job openings in Missouri as of July 2026, with employment types broken down into 3% As Needed, 74% Full Time, 18% Part Time, and 5% Contract. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $80,239 per year, or $38.6 per hour.

Clinical Lead II (Oncology)

11 Premier Research International LLC

California, MO โ€ข On-site

$104.40 - $127.60/hr

Other

Medical, Retirement, PTO

Posted 4 days ago


Job description

Premier Research is looking for a Clinical Lead II (Oncology) to join our Clinical Management team.

What You'll Be Doing:
  • Serve as the initial point of contact for all site management and monitoring quality concerns, including initiation and oversight of site performance improvement plans (sPIP).
  • Plan, present, and participate in sponsor calls, representing Clinical and SSU functions by providing status updates on clinical deliverables.
  • Oversee the quality of clinical monitoring, central monitoring, and site management deliverables through dashboards and reporting tools.
  • Contribute strongly to the central monitoring plan.
  • Monitor clinical operations metrics, activities, and timelines on a regular basis; track data entry timelines, open actions, protocol deviations, queries aging reports, SDR/SDV backlog, and monitoring visit report turnaround timelines.
  • Ensure a state of audit readiness for both Premier and sites.
  • Review and respond to audit findings and support sites in remediation or responses to any site audit findings.
  • Escalate through established channels CRA/CM/SSU performance concerns, quality events, data breaches, serious breaches, scientific misconduct, or any other event requiring prompt assessment and reporting.
What We Are Searching For:
  • Bachelorโ€™s degree, or its international equivalent, from an accredited institution in a clinical, biological, scientific, or healthโ€‘related field; or equivalent work experience.
  • At least 2 years of experience as a Clinical Lead.
  • Prior onsite monitoring experience, including experience with Riskโ€‘Based Monitoring, is preferred.
  • Strong leadership skills and the ability to persuade and motivate team members and sites to achieve targets.
  • Working knowledge of clinical financials, including budgets, passโ€‘throughs, and resource management.
  • Ability to multitask and work effectively in a fastโ€‘paced environment with changing priorities.
  • Required therapeutic area: Oncology.
Compensation and Benefits:
  • Annualized minimum base pay: $116,000 USD.
  • Comprehensive benefits package that may include health insurance, retirement plans, and paid time off.
Equal Employment Opportunity Statement:

Premier Research is a proud equal opportunity employer that is compliant with all federal guidelines. All qualified applicants will receive equitable consideration without regard to race, color, religion, sexual orientation, gender identity, national origin, disability, or veteran status.

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