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Clinical Lab Technologist Jobs in Rochester, MN (NOW HIRING)

Mayo Clinic

Clinical Lab Technologist

Lake City, MN

$66K - $99K/yr

Perform clinical testing using a variety of automated, semi-automated, and/or manual technology as defined by current job assignment. Perform quality control (QC) and quality assurance (QA) ...

Mayo Clinic

Clinical Lab Technologist

Lake City, MN · On-site

Perform clinical testing using a variety of automated, semi-automated, and/or manual technology as defined by current job assignment. Perform quality control (QC) and quality assurance (QA) ...

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Clinical Lab Technologist information

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$19

$47

$70

How much do clinical lab technologist jobs pay per hour?

As of Jul 22, 2026, the average hourly pay for clinical lab technologist in Rochester, MN is $47.56, according to ZipRecruiter salary data. Most workers in this role earn between $39.09 and $56.44 per hour, depending on experience, location, and employer.

What are Clinical Lab Technologists?

Clinical Lab Technologists are healthcare professionals who perform complex tests and procedures in laboratories to help diagnose, treat, and prevent diseases. They analyze samples such as blood, urine, and tissue using sophisticated equipment and techniques. Their work is essential for providing accurate data to doctors and other medical staff, making them a critical part of patient care teams. In addition to running tests, they often ensure quality control, maintain lab equipment, and may help develop new testing methods.

Who gets paid more, MLT or MLS?

Medical Laboratory Technologists (MLTs) and Medical Laboratory Scientists (MLSs) are often used interchangeably, but in some regions, MLSs typically have higher salaries due to advanced education and certification requirements. Generally, MLSs tend to earn more than MLTs because they usually hold a bachelor's degree and have more responsibilities in complex testing and analysis.

What are some common challenges Clinical Lab Technologists face in ensuring test accuracy and reliability?

Clinical Lab Technologists frequently encounter challenges such as managing high sample volumes while adhering to strict quality control protocols. They must remain vigilant for equipment malfunctions, specimen contamination, or inconsistent results. Staying up-to-date with evolving laboratory technologies and maintaining clear communication with healthcare teams are essential for minimizing errors and ensuring that test results are both accurate and timely.

What is the difference between Clinical Lab Technologist vs Medical Laboratory Technician?

AspectClinical Lab TechnologistMedical Laboratory Technician
CredentialsBachelor's degree in medical technology or related field; certification often requiredAssociate's degree in medical laboratory technology; certification preferred
Work EnvironmentHospitals, diagnostic laboratories, research facilitiesHospitals, clinics, smaller labs
Job ResponsibilitiesPerform complex tests, analyze results, supervise technologistsPrepare samples, perform routine tests, record data

The main difference between a Clinical Lab Technologist and a Medical Laboratory Technician lies in their education, responsibilities, and level of supervision. Clinical Lab Technologists typically hold a bachelor's degree and perform more complex testing and analysis, often supervising technicians. Medical Laboratory Technicians usually have an associate's degree and handle routine testing tasks. Both roles are essential in laboratory settings, but the technologist's role involves higher-level responsibilities and expertise.

What are the key skills and qualifications needed to thrive as a Clinical Lab Technologist, and why are they important?

To thrive as a Clinical Lab Technologist, you need strong analytical skills, attention to detail, and a bachelor's degree in medical technology or a related field, often accompanied by professional certification such as ASCP. Familiarity with laboratory information systems (LIS), automated analyzers, and quality control protocols is essential. Strong problem-solving abilities, communication skills, and a commitment to accuracy help you excel in this role. These competencies ensure reliable diagnostic results, patient safety, and effective collaboration within healthcare teams.

What does a clinical lab technologist do?

A clinical lab technologist performs laboratory tests on blood, tissues, and other specimens to help diagnose, treat, and monitor diseases. They operate and maintain laboratory equipment, follow safety protocols, and ensure accurate test results, often working in hospitals, clinics, or diagnostic laboratories. Certification and attention to detail are essential in this role.

Where do CLS get paid the most?

Clinical Lab Technologists tend to earn the highest salaries in regions with a high cost of living and strong healthcare industries, such as metropolitan areas or states with advanced medical facilities. Salaries can also vary based on experience, certifications, and the specific employer or laboratory setting.

Is a CLS license worth it?

A Clinical Lab Technologist (CLS) license is valuable for employment as it demonstrates compliance with state or national certification requirements, often leading to better job prospects and higher pay. Licensing typically requires passing a certification exam and maintaining ongoing education, which ensures competency in laboratory procedures and safety standards.
What cities near Rochester, MN are hiring for Clinical Lab Technologist jobs? Cities near Rochester, MN with the most Clinical Lab Technologist job openings:
Clinical Lab Technologist jobs near you
Infographic showing various Clinical Lab Technologist job openings in Rochester, MN as of July 2026, with employment types broken down into 2% As Needed, 74% Full Time, 17% Part Time, and 7% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $98,934 per year, or $47.6 per hour.
Clinical Lab Technologist

Clinical Lab Technologist

Mayo Clinic

Lake City, MN

$66K - $99K/yr

Other

Medical, Dental, Vision, Retirement

Posted 8 days ago

Mayo Clinic rating

7.9

Company rating: 7.9 out of 10

Based on 690 frontline employees who took The Breakroom Quiz

105th of 888 rated healthcare providers

Job description

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

Responsibilities

Collect, receive, and process the appropriate specimens (body fluids, blood, urine, swabs, stools, etc.) in a safe, accurate, and professional manner with the proper technique. Perform clinical testing using a variety of automated, semi-automated, and/or manual technology as defined by current job assignment. Perform quality control (QC) and quality assurance (QA) procedures to ensure accurate reporting of test results. Perform daily, weekly, and monthly instrument maintenance of various equipment. Troubleshoot machines and solve technical issues. Follow standard precautions at all times. Participate in external quality controls like CAP proficiencies and perform laboratory competencies. Maintain laboratory documentation and files. Display competency in phlebotomy for all age ranges from pediatrics to geriatrics. Conduct validation, verification, and correlation of the equipment. Communicate effectively to providers, nurses, and colleagues regarding critical values and clinical care. Perform in different sections of the laboratory: Blood Banking, Clinical Chemistry, Hematology, Microbiology/PCR, Urinalysis, and Receiving and Processing Specimens. Perform operational support functions to facilitate workflow. Must be available to work weekends, overnight, and holiday shifts.

Visa sponsorship is not available for this role. 


Qualifications

Bachelor's degree in Medical Technology (MT), Medical Laboratory Science (MLS), or Clinical Laboratory Science (CLS) OR a Bachelor's degree in a field related to medical laboratory science along with a Certificate in Medical Laboratory Science (MLS), Clinical Laboratory Science (CLS), or Medical Technology (MT), as recognized by the National Accrediting Agency for Clinical Laboratory Sciences (NAACLS). 

Skills: Microscopic analysis;

Proficiency in medical laboratory procedures and the use of medical laboratory instruments;

Applied knowledge of Blood Bank theory;

Applied chemistry knowledge in the context of a medical laboratory;

Microbiology/PCR skills;

Applied Hematology/Coagulation knowledge in the context of a medical laboratory;

Demonstrated proficiency in phlebotomy and specimen collection techniques in the context of a medical laboratory; Applied Urinalysis knowledge in the context of a medical laboratory.

Visa sponsorship is not available for this role. 


Exemption Status
Nonexempt
Compensation Detail
$66,123.20-$99,236.80/year
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
Varies
Weekend Schedule
Varies
International Assignment
No
Site Description
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the 'EOE is the Law'.  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Recruiter
Tricia HardingQualifications:

Bachelor's degree in Medical Technology (MT), Medical Laboratory Science (MLS), or Clinical Laboratory Science (CLS) OR a Bachelor's degree in a field related to medical laboratory science along with a Certificate in Medical Laboratory Science (MLS), Clinical Laboratory Science (CLS), or Medical Technology (MT), as recognized by the National Accrediting Agency for Clinical Laboratory Sciences (NAACLS). 

Skills: Microscopic analysis;

Proficiency in medical laboratory procedures and the use of medical laboratory instruments;

Applied knowledge of Blood Bank theory;

Applied chemistry knowledge in the context of a medical laboratory;

Microbiology/PCR skills;

Applied Hematology/Coagulation knowledge in the context of a medical laboratory;

Demonstrated proficiency in phlebotomy and specimen collection techniques in the context of a medical laboratory; Applied Urinalysis knowledge in the context of a medical laboratory.

Visa sponsorship is not available for this role. 

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About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919

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