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Clinical Database Programmer Jobs in Durham, NC (NOW HIRING)

CYNET SYSTEMS

MS Power Platform Developer

Raleigh, NC · On-site

$90 - $95/hr

Knowledge of SQL database structure. * Strong problem-solving skills and attention to detail ... We deliver agile, scalable talent solutions across IT, engineering, life sciences, clinical, and ...

Labcorp

Principal Software Engineer

Durham, NC · On-site

$130K - $174K/yr

... clinical workflows. * Experience with Terraform for infrastructure as code and AWS resource ... Database migration strategies for zero-downtime deployments in 24/7 environments. * Experience with ...

Labcorp

Principal Software Engineer

Durham, NC · On-site

$130K - $174K/yr

... clinical workflows. * Experience with Terraform for infrastructure as code and AWS resource ... Database migration strategies for zero-downtime deployments in 24/7 environments. * Experience with ...

Teleflex

Engineer 2, Sustaining, R&D

Morrisville, NC · On-site

$85K - $105K/yr

Vascular & Emergency Medicine - Built on a legacy of innovation and clinical excellence, the ... Utilizes appropriate PLM, ERP and other product-related database systems. • Conducts research on ...

Teleflex

Engineer 2, Sustaining, R&D

Morrisville, NC · On-site

$85K - $105K/yr

Vascular & Emergency Medicine - Built on a legacy of innovation and clinical excellence, the ... Utilizes appropriate PLM, ERP and other product-related database systems. Conducts research on ...

Fujifilm

Senior Software Engineer, RIS

Durham, NC · On-site

$118K - $156K/yr

Design and implement product features from internal and external customer requirements and clinical ... Entity Relationship Modeling and Principles of Relational Database * Agile/SCRUM work practices

Merck & Co.

Senior Software Engineer, RIS

Durham, NC · On-site

$80 - $110/hr

Design and implement product features from internal and external customer requirements and clinical ... Entity Relationship Modeling and Principles of Relational Database * Agile/SCRUM work practices

Fujifilm

Senior Software Engineer, RIS

Durham, NC · On-site

$118K - $156K/yr

Design and implement product features from internal and external customer requirements and clinical ... Entity Relationship Modeling and Principles of Relational Database * Agile/SCRUM work practices

Fujifilm

Senior Software Engineer, RIS

Durham, NC · On-site

$118K - $156K/yr

Design and implement product features from internal and external customer requirements and clinical ... Entity Relationship Modeling and Principles of Relational Database * Agile/SCRUM work practices

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All JobsClinical Database Programmer JobsClinical Database Programmer Jobs in Durham, NC

Clinical Database Programmer information

See Durham, NC salary details

$63K

$107.8K

$192.1K

How much do clinical database programmer jobs pay per year?

As of Sep 1, 2026, the average yearly pay for clinical database programmer in Durham, NC is $107,788.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,500.00 and $163,100.00 per year, depending on experience, location, and employer.

What is a clinical database programmer?

A Clinical Database Programmer is responsible for designing, developing, and maintaining databases used in clinical trials. They ensure that data is collected, stored, and managed efficiently while complying with regulatory standards such as CDISC and FDA guidelines. Their role involves creating database structures, writing validation checks, and supporting data analysis to ensure accurate and reliable clinical trial results. They often work with clinical data managers, biostatisticians, and regulatory teams.

What are the key skills and qualifications needed to thrive as a clinical database programmer?

To excel as a Clinical Database Programmer, you need a bachelor's degree in computer science or a related field, experience in database design, and a strong understanding of clinical data standards. Proficiency in database management systems (such as Oracle or SQL), knowledge of electronic data capture (EDC) tools like Medidata Rave, and familiarity with programming languages like SAS or SQL are commonly required, along with certifications such as CDISC or Medidata Solutions. Attention to detail, problem-solving ability, and strong communication skills are valuable soft skills for this role. Mastering these competencies is vital for ensuring high-quality, regulatory-compliant clinical trial data and effective collaboration within multidisciplinary research teams.

What are common responsibilities and team interactions for a clinical database programmer in a typical workweek?

As a Clinical Database Programmer, your primary responsibilities usually include designing, building, and validating clinical trial databases, ensuring data is collected and managed in compliance with industry standards and regulatory requirements. You will frequently collaborate with clinical data managers, biostatisticians, and study coordinators to define data collection requirements and resolve data discrepancies. Team meetings and cross-functional communication are integral parts of the role, as you work together to maintain database integrity throughout the study lifecycle. This collaborative environment provides valuable experience in both technical problem-solving and teamwork, often paving the way for advancement into senior programming or data management positions.

What are popular job titles related to Clinical Database Programmer jobs in Durham, NC?

For Clinical Database Programmer jobs in Durham, NC, the most frequently searched job titles are:

What job categories do people searching Clinical Database Programmer jobs in Durham, NC look for?

The top searched job categories for Clinical Database Programmer jobs in Durham, NC are:

What cities near Durham, NC are hiring for Clinical Database Programmer jobs?

Cities near Durham, NC with the most Clinical Database Programmer job openings:

Clinical Database Programmer jobs near you
Infographic showing various Clinical Database Programmer job openings in Durham, NC as of August 2026, with employment types broken down into 100% Full Time. Highlights an 67% In-person, and 33% Remote job distribution, with an average salary of $107,788 per year, or $51.8 per hour.

Data Engineer 1, Operational Technology - Operations #4941

GRAIL

Durham, NC • On-site

$110K - $132K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 5 days ago

Job description

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.
 
We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine's greatest challenges.
 
GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.
 
For more information, please visit grail.com

As a Data Engineer on the Operational Technology team, you will build and maintain the data pipelines that connect GRAIL's lab instruments, automation systems, and operational platforms to a trusted, well modeled data foundation. You will own well scoped ingestion and transformation pipelines end to end, partnering with systems engineers, lab operations, data scientists, and automation engineers to keep data flowing reliably from the lab floor to the analytics and AI systems that depend on it. This is a hands-on role for an engineer who is ready to take ownership of real data infrastructure and grow quickly in a fast paced, regulated environment. Expect to work alongside a talented and highly motivated team that moves quickly.

This role is based on-site in RTP, North Carolina, Monday through Friday. The position participates in an on-call rotation and may occasionally require weekend or holiday support for production incidents, maintenance, or critical deployments.

Responsibilities:

  • Build and maintain data pipelines that ingest and integrate information from laboratory instruments, automation systems, sequencers, operational platforms, APIs, autonomous robotics platforms, databases and file based data sources.

  • Support downstream analytics, reporting, and AI systems by delivering clean, trustworthy datasets and timely data extracts for troubleshooting, root-cause investigations and platform improvements.

  • Develop and optimize SQL and transformation logic to cleanse, standardize, and model raw instrument and production data into reliable, well structured datasets.

  • Build and support datasets and data models used by operational dashboards, analytics, process monitoring, troubleshooting, and governed AI enabled workflows.

  • Implement orchestration, testing, monitoring and alerting so that data failures, freshness issues, schema changes, and incomplete processing are identified early.

  • Implement data validation and quality checks to ensure datasets are accurate, complete, and reliable.

  • Document pipelines, data models, and datasets to support reproducibility and compliance with ISO, CLIA, CAP, NYS, GMP, and FDA requirements.

  • Continuously improve your technical skills and the team's engineering practices.

Required Qualifications:

  • Degree in Computer Science, Mathematics, Software Engineering, Data Science, Life Sciences, Physics or similar field.

  • 1+ years of relevant professional, internship, academic, or project experience in data engineering, analytics engineering, software development, or a related field, or equivalent practical experience.

  • Proficiency in SQL.

  • Working proficiency with one or more programming languages, such as Python, Rust, C++, or similar.

  • Basic understanding of ETL or ELT pipelines, relational databases, and structured or semi-structured data.

  • Strong attention to detail and a commitment to data quality, reliability and accuracy.

  • Ability to collaborate effectively in teams of technical and non-technical individuals, and comfortable working in a rapidly changing environment with dynamic objectives and fast iteration.

  • Ability to investigate technical problems methodically, continuously learn and communicate clearly.

  • A highly analytical mindset and eagerness to solve technical problems.

Preferred Qualifications:

  • Familiarity with data pipeline orchestration and transformation tools such as Airflow, dbt, or comparable technologies.

  • Familiarity with cloud data platforms, object storage and warehouses such as AWS S3, Redshift, Glue, Snowflake or comparable technologies.

  • Familiarity integrating AI/agentic tooling into the data engineering SDLC.

  • Experience with semantic data modeling, data lineage, and automated data quality testing. 

  • Familiarity with statistical methods or basic process analytics.

  • Exposure to manufacturing, clinical laboratory operations, diagnostics, or biotechnology.

  • Experience with version control systems such as Git and collaborative development practices.

  • Basic understanding of APIs, file transfers, networking and system integrations.

The expected, full-time, annual base pay scale for this position is $86K - $106K. Actual base pay will consider skills, experience, and location.


This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate's qualifications. Employees in this role are also eligible for GRAIL's comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.

GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at [email protected] if you require an accommodation to apply for an open position.

GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!

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