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Clinical Database Programmer Jobs in California (NOW HIRING)

Collabera

Clinical Data Manager

Irvine, CA

Work closely with clinical project team and database programmers to provide edit check requirements and specifications at the time of study database development and Post production changes. Ensure ...

BetterHelp

Senior Database Engineer

San Jose, CA · On-site

$124K - $168K/yr

As a Senior Database Engineer at BetterHelp, you'll join a diverse team of licensed clinicians, engineers, product pros, creatives, marketers, and business leaders who share a passion for expanding ...

BetterHelp

Senior Database Engineer

San Jose, CA

$124K - $168K/yr

As a Senior Database Engineer at BetterHelp, you'll join a diverse team of licensed clinicians, engineers, product pros, creatives, marketers, and business leaders who share a passion for expanding ...

QuidelOrtho

Senior Database Design Engineer

San Diego, CA · Remote

$112K - $152K/yr

The Opportunity QuidelOrtho unites the strengths of Quidel Corporation and Ortho Clinical ... Join our mission as our next Senior Database Design Engineer to join our R&D Instrument Platforms ...

Xencor

Sr. Director, Clinical Science (Oncology)

San Diego, CA · On-site

$84K - $115K/yr

More than 20 XmAb drug candidates engineered with our technology are in clinical development, and ... Provides medical input for the clinical database build, CRFs, monitoring plan, data management plan ...

Recor Medical

Senior Clinical Programmer

Palo Alto, CA

$145K - $156K/yr

Create and maintain data integration pipelines between clinical systems and internal databases * Provide technical guidance to junior programmers on clinical data processing methodologies * Other ...

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Clinical Database Programmer information

See California salary details

$68.6K

$117.4K

$209.2K

How much do clinical database programmer jobs pay per year?

As of Jun 12, 2026, the average yearly pay for clinical database programmer in California is $117,404.00, according to ZipRecruiter salary data. Most workers in this role earn between $79,000.00 and $177,600.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Clinical Database Programmer position, and why are they important?

To excel as a Clinical Database Programmer, you need a bachelor's degree in computer science or a related field, experience in database design, and a strong understanding of clinical data standards. Proficiency in database management systems (such as Oracle or SQL), knowledge of electronic data capture (EDC) tools like Medidata Rave, and familiarity with programming languages like SAS or SQL are commonly required, along with certifications such as CDISC or Medidata Solutions. Attention to detail, problem-solving ability, and strong communication skills are valuable soft skills for this role. Mastering these competencies is vital for ensuring high-quality, regulatory-compliant clinical trial data and effective collaboration within multidisciplinary research teams.

What is a Clinical Database Programmer job?

A Clinical Database Programmer is responsible for designing, developing, and maintaining databases used in clinical trials. They ensure that data is collected, stored, and managed efficiently while complying with regulatory standards such as CDISC and FDA guidelines. Their role involves creating database structures, writing validation checks, and supporting data analysis to ensure accurate and reliable clinical trial results. They often work with clinical data managers, biostatisticians, and regulatory teams.

What are common responsibilities and team interactions for a Clinical Database Programmer in a typical workweek?

As a Clinical Database Programmer, your primary responsibilities usually include designing, building, and validating clinical trial databases, ensuring data is collected and managed in compliance with industry standards and regulatory requirements. You will frequently collaborate with clinical data managers, biostatisticians, and study coordinators to define data collection requirements and resolve data discrepancies. Team meetings and cross-functional communication are integral parts of the role, as you work together to maintain database integrity throughout the study lifecycle. This collaborative environment provides valuable experience in both technical problem-solving and teamwork, often paving the way for advancement into senior programming or data management positions.

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Clinical Database Programmer jobs near you
Infographic showing various Clinical Database Programmer job openings in California as of June 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $117,404 per year, or $56.4 per hour.
Sr. Principal Specialist, Clinical Database Programming

Sr. Principal Specialist, Clinical Database Programming

Neurocrine Biosciences, Inc.

San Diego, CA • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 29 days ago

Job description

Who We Are:
At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.
What We Do:
Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X and Facebook. (*in collaboration with AbbVie)
About the Role:
Provides strategic and operational leadership for the clinical database programming function across Neurocrine's clinical development portfolio. This is a hands-on role, and accountable for defining standards, governance, and long-term strategy to ensure high-quality, compliant, and scalable clinical databases. Serves as a recognized expert, influencing cross-functional decision-making and driving continuous improvement, innovation, and inspection readiness across all therapeutic areas and development phases.
Your Contributions (include, but are not limited to):
  • Provide strategic leadership and functional ownership of clinical database programming across all clinical programs and therapeutic areas
  • Define, implement, and oversee standards, processes, and best practices for database programming to ensure consistency, quality, and regulatory compliance
  • Mentor, train, and develop team members (as required)
  • Lead and perform clinical database programming activities, including database build, data review and cleaning programs, validation and derivation procedures, database migrations, Targeted SDV configuration, SAS dataset creation, and Global Library maintenance, ensuring the highest standards of quality, compliance, and inspection readiness. Partner within Data Management and Analytics & Data Sciences (ADS) as well as cross-functional leadership to help develop long-arrange plans, resourcing, and operating models aligned with corporate objectives
  • Oversee database timelines, risks, and dependencies; proactively identify and mitigate complex technical/systemic issues that could impact quality, inspection readiness, or submissions
  • Oversee vendor quality and performance, including CROs and consultants, ensuring alignment with internal standards and expectations
  • Lead evaluation, implementation, validation, and adoption of new technologies, platforms, and system enhancements related to data collection, validation, integration, and review
  • Assess the impact of and oversee software updates, including impact to team processes and workflows, and document findings, risks, and recommended actions
  • Ensure inspection readiness and regulatory compliance through proactive oversight of SOPs, work instructions, documentation practices, and quality metrics
  • Act as a liaison across Clinical Data Management (and ADS), Clinical Operations, DSPV, Regulatory, IT, and external partners
  • Stay current with industry trends and regulatory expectations; translate insights into actionable improvements for Neurocrine
  • Provide hands-on technical guidance and expertise in high-risk or high-complexity situations to ensure database quality and an appropriate resolution.
  • other duties as assigned

Requirements:
  • BS/BA degree AND 8+ years of relevant experience OR
  • Master's AND 6+ years of related experience OR
  • PharmD or PhD AND 4+ years of related experience
  • Demonstrated success as a leader and influencing cross-functional teams without direct authority
  • Strong leadership, communication, problem-solving, and decision-making skills
  • Anticipates business and industry issues; recommends relevant process / technical / service improvements
  • Demonstrates broad expertise or unique knowledge
  • Considered an expert within the company and may have external presence in area of expertise
  • Applies in-depth expertise in discipline and broad knowledge of other closely related areas to improve efficiency of team
  • Ability to work as part of and lead multiple teams
  • Strong leadership, mentoring skills and abilities; typically leads lower levels and/or indirect teams
  • Excellent computer skills
  • Excellent communications, problem-solving, analytical thinking skills
  • Sees broader picture and longer-term impact on division/company
  • Ability to meet multiple deadlines across a variety of projects/programs, with a high degree of accuracy and efficiency
  • Excellent project management, strong project leadership skills
  • Advanced knowledge of Medidata Rave and clinical database programming within a pharmaceutical or biotechnology environment (CRO or sponsor)
  • Extensive understanding of the end-to-end drug development process and regulatory submission requirements
  • Expert knowledge of GCP and applicable FDA/EMA regulations and guidance
  • Demonstrated experience with CDISC standards (CDASH, SDTM) and organizational implementation of standards
  • Proven ability to define and govern SOPs, work instructions, and functional standards across the organization
  • Advanced hands-on experience with clinical database programming tools, including SAS and SQL (or other programming language)
  • Experience with data visualization tools
  • Experience leading enterprise-wide system implementations or major upgrades
  • Experience with custom programming a plus

#LI-RS1
Neurocrine Biosciences is an EEO/Disability/Vets employer.
We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.
The annual base salary we reasonably expect to pay is $158,100.00-$216,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 30% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

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