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Cleanroom Manufacturing Jobs in Chicago, IL (NOW HIRING)

Aerotek

Picker

Waukegan, IL · On-site

$19 - $20/hr

Manufacturing or production experience. * Cleanroom experience, including gowning and contamination-control practices. * Medical device, healthcare, or kit assembly experience. Why Join Us? * Work in ...

Element Solutions

Manufacturing Engineer

Itasca, IL · On-site

$71K - $91K/yr

Provide manufacturing input, assess risks, and support project execution * Monitor KPIs ... Familiar with cleanroom operations, contamination control, and regulatory standards * Preferred ...

Element Solutions Inc

Manufacturing Engineer

Itasca, IL

$71K - $91K/yr

Provide manufacturing input, assess risks, and support project execution * Monitor KPIs ... Familiar with cleanroom operations, contamination control, and regulatory standards * Preferred ...

Nemera

Warehouse Trainer (Days)

Buffalo Grove, IL

Works in a cleanroom manufacturing and warehouse environment that may include moderate noise levels ADDITIONAL NOTES This is not designed to cover or contain a comprehensive listing of activities ...

Nemera

Warehouse Trainer (Days)

Buffalo Grove, IL · On-site

$24 - $30/hr

Works in a cleanroom manufacturing and warehouse environment that may include moderate noise levels ADDITIONAL NOTES This is not designed to cover or contain a comprehensive listing of activities ...

Element Solutions Inc

Manufacturing Engineer

Itasca, IL

$71K - $91K/yr

Provide manufacturing input, assess risks, and support project execution * Monitor KPIs ... Familiar with cleanroom operations, contamination control, and regulatory standards * Preferred ...

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All JobsCleanroom Manufacturing JobsCleanroom Manufacturing Jobs in Chicago, IL

Cleanroom Manufacturing information

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$14

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$35

How much do cleanroom manufacturing jobs pay per hour?

As of Sep 1, 2026, the average hourly pay for cleanroom manufacturing in Chicago, IL is $25.70, according to ZipRecruiter salary data. Most workers in this role earn between $20.82 and $29.71 per hour, depending on experience, location, and employer.

What is cleanroom manufacturing?

Cleanroom manufacturing refers to the production of goods in a controlled environment where contaminants like dust, airborne microbes, and chemical vapors are minimized. These cleanrooms are specially designed spaces with strict cleanliness standards, often used in industries such as semiconductor, pharmaceutical, medical device, and aerospace manufacturing. Employees working in cleanroom manufacturing must wear specialized clothing and follow rigorous procedures to prevent contamination. This ensures that products meet high quality and safety standards required for sensitive applications.

What are the key skills and qualifications needed to thrive as a cleanroom manufacturing technician?

To thrive as a Cleanroom Manufacturing Technician, you need attention to detail, knowledge of aseptic techniques, and a high school diploma or equivalent, often supplemented by specialized training. Familiarity with cleanroom protocols, use of personal protective equipment (PPE), and experience operating manufacturing equipment are typically required. Strong teamwork, reliability, and the ability to follow strict procedures set standout professionals apart in this field. These skills are crucial to maintaining product quality, safety, and regulatory compliance in controlled manufacturing environments.

What are some common challenges faced in cleanroom manufacturing, and how can new employees effectively adapt?

Cleanroom manufacturing professionals often face challenges such as maintaining strict contamination controls, adhering to rigorous gowning procedures, and following detailed protocols without deviation. New employees may find the controlled environment and need for constant vigilance demanding, but thorough training and mentorship can ease the transition. Collaborating closely with experienced team members and consistently following established procedures helps ensure product quality and safety, while also fostering a supportive work environment.

What is the difference between Cleanroom Manufacturing vs Cleanroom Technician?

AspectCleanroom ManufacturingCleanroom Technician
CertificationsISO certifications, GMP trainingISO certifications, GMP training
Work EnvironmentControlled cleanroom facilities, manufacturing linesControlled cleanroom environments, equipment setup and maintenance
Job FocusProduction, assembly, process controlMonitoring, testing, equipment calibration
Employer & IndustryPharmaceutical, biotech, electronics manufacturingPharmaceutical, biotech, electronics manufacturing

Both roles operate within cleanroom environments and require similar certifications. However, Cleanroom Manufacturing focuses on production and assembly processes, while Cleanroom Technicians handle testing, equipment maintenance, and monitoring to ensure quality standards are met.

What are popular job titles related to Cleanroom Manufacturing jobs in Chicago, IL?

For Cleanroom Manufacturing jobs in Chicago, IL, the most frequently searched job titles are:

What job categories do people searching Cleanroom Manufacturing jobs in Chicago, IL look for?

The top searched job categories for Cleanroom Manufacturing jobs in Chicago, IL are:

What cities near Chicago, IL are hiring for Cleanroom Manufacturing jobs?

Cities near Chicago, IL with the most Cleanroom Manufacturing job openings:

Cleanroom Manufacturing jobs near you
Infographic showing various Cleanroom Manufacturing job openings in Chicago, IL as of August 2026, with employment types broken down into 89% Full Time, 6% Part Time, 3% Contract, and 2% Nights. Highlights an 95% Physical, 2% Hybrid, and 3% Remote job distribution, with an average salary of $53,454 per year, or $25.7 per hour.

Manufacturing Associate I (DS) - Chicago, IL

Unicon Pharma Inc.

Chicago, IL • On-site

Contractor

Re-posted 21 days ago

Job description

Title: Manufacturing Associate I (DS)

Location: Chicago, IL, 60616

Position Summary:

The Manufacturing Associate I (DS), will be responsible for the manufacturing of Biotechnology products for clinical and commercial human use.

Employee applies aseptic techniques while working in controlled and classified environments, which require cleanroom gowning and some aseptic gowning.

Must comply with Client policies, procedures (SOP), FDA current Good Manufacturing Practices (cGMP), and any other government requirement.

Essential Duties & Responsibilities

Follow work instructions, production specifications, and standard operating procedures (SOPs) to perform key responsibilities and maintain quality data while meeting production goals and timelines and minimizing downtime/delays.

Work instructions include but are not limited to:

  • Weighing and dispensing of materials
  • Media and buffer preparation
  • Operation of filtration systems (such as dead end filtration, depth filtration, tangential flow filtration)
  • Inoculation, fermentation, harvest, and homogenization of cytokine cells
  • Setup and operation of chromatography columns
  • Aseptic final filtration of intermediates and drug substances
  • Monitor product for quality output using PLC controls, HMI interfacing, integrity testing, and in process testing (pH, Conductivity, and Spectroscopy).
  • Properly handle and discard hazardous materials (i.e, buffers, chemicals, etc.) in accordance with EHS guidelines. Remove used and soiled materials from manufacturing areas.
  • Follow daily and weekly cleaning routines for cleanrooms and equipment to maintain the required conditions for cleanroom manufacturing.
  • Verify raw materials and commodities; accurately enter raw material and commodities data in MES on daily basis
  • Completes Batch Records and other cGMP documentation accurately and in a timely manner.
  • Reports nonconformances or events that arise during the shift to the Supervisor
  • Complies with all safety, cGMP and Company policies, practices and procedures.
  • Performs other functions as required or assigned

Education:

  • Associate degree or higher in Biology, Chemistry, Biotechnology or related preferred
  • Or an equivalent of 0 – 2 years of industry experience required
  • Aseptic techniques and cleanroom manufacturing experience is preferred.

Language:

  • Basic verbal and written communication skills in English with the ability to understand technical information, procedures, batch records, and other documents in English.
  • Excellent interpersonal skills, effective communication with peers and supervision.

Reasoning Skills:

  • The candidate should have the ability to operate complex systems and equipment in accordance with current GMPs, SOPs, and safety guidelines under minimum supervision.
  • Basic skills for identifying problems and troubleshooting of the equipment and manufacturing processes
  • Ability to work independently, within prescribed guidelines, or as a team member and the demonstrated ability to follow detailed directions.

Computer and/or Technical Skills:

  • Skills for working with Computer systems, such as: Delta, PCR, POMS, LIMS, SAP, etc.
  • Operation and understanding of word processing, spreadsheets, and data management
  • Knowledge of GMP and safety requirements.
  • Knowledge of biotechnology operations such as, Aseptic Filtration Systems, Aseptic Sampling, Filter Integrity Testing, Fermentation Process, Inoculation Process, Chromatography Columns, Mixing systems, Weigh Scales, etc.

Work Environment & Physical Demands:

  • General work environment and physical demands as required to successfully perform the essential functions of this job.
  • Ability to work flexible hours as needed.
  • Ability to work under pressure and meet deadlines.