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Cell Therapy Process Development Jobs in California

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Cell Therapy Process Development information

What are the key skills and qualifications needed to thrive as a cell therapy process development professional?

To thrive in Cell Therapy Process Development, you need a solid background in cell biology, biotechnology, or a related field, often supported by a relevant degree and experience with cell culture techniques. Familiarity with bioprocessing equipment, Good Manufacturing Practice (GMP) regulations, and analytical tools such as flow cytometry and PCR is typically required. Strong problem-solving skills, attention to detail, and effective teamwork enhance performance in this collaborative and innovative environment. These competencies ensure the safe and efficient development of cell therapies, meeting rigorous quality standards and advancing clinical applications.

What are some typical challenges faced by professionals in cell therapy process development, and how are they addressed?

Professionals in Cell Therapy Process Development often encounter challenges such as scaling up production processes from laboratory to clinical or commercial scale while maintaining product quality and consistency. Additional hurdles include adhering to strict regulatory requirements and managing complex collaborations across cross-functional teams, like quality assurance, regulatory affairs, and manufacturing. These challenges are typically addressed through rigorous process optimization, thorough documentation, and ongoing communication with stakeholders to ensure that all aspects of the process meet industry standards and regulatory expectations.

What is the difference between Cell Therapy Process Development vs Cell Therapy Manufacturing Specialist?

AspectCell Therapy Process DevelopmentCell Therapy Manufacturing Specialist
CredentialsTypically requires a degree in biology, biochemistry, or biomedical engineering; certifications in GMP or cell therapy are commonSimilar credentials; often holds degrees in related fields and GMP certifications
Work EnvironmentResearch labs, development facilities, early-stage process optimizationManufacturing plants, production floors, quality control labs
Industry UsageFocuses on developing and optimizing cell therapy processesInvolved in large-scale production and process execution

Cell Therapy Process Development professionals focus on designing and refining cell therapy procedures, while Cell Therapy Manufacturing Specialists handle the production and quality assurance in manufacturing settings. Both roles require similar educational backgrounds and certifications but differ mainly in their work environment and specific responsibilities.

What is cell therapy process development?

Cell Therapy Process Development refers to the design, optimization, and scaling up of manufacturing processes for cell-based therapies, such as CAR-T cells or stem cell products. Professionals in this field work on translating laboratory research into reproducible, efficient, and safe production methods that meet regulatory standards. This involves working with cell culture techniques, bioreactors, quality control, and process validation to ensure that therapies can be produced consistently for clinical and commercial use. The goal is to develop robust processes that deliver safe and effective cell therapies to patients.
What cities in California are hiring for Cell Therapy Process Development jobs? Cities in California with the most Cell Therapy Process Development job openings:
Infographic showing various Cell Therapy Process Development job openings in California as of August 2026, with employment types broken down into 61% Full Time, and 39% Part Time. Highlights an 100% In-person job distribution.

Senior Principal Scientist: Metabolomics/Cell Therapy Media Development

Genentech

South San Francisco, CA • On-site

$143K - $266K/yr

Full-time

Re-posted 2 days ago


Genentech rating

8.8

Company rating: 8.8 out of 10

Based on 22 frontline employees who took The Breakroom Quiz

11th of 86 rated pharmaceutical


Job description

This role is a vital part of our Cell Therapy Process Development team within Pharma Technical Cell and Gene Therapy Development (PTCC), which is committed to advancing next-generation cell therapies through innovative metabolomics research and media optimization.

As a member of this team, you will lead cutting-edge efforts to develop and optimize cell culture media platforms while collaborating closely with key stakeholders across Analytical Development, Research, Manufacturing Operations, and cross-functional teams within Genentech and Roche. You will serve as the primary in-house expert on state-of-the-art cell therapy media development practices, translating deep scientific expertise into strategic innovations that enable breakthrough therapies to reach patients. This position offers the opportunity to shape the future of cell therapy manufacturing while fostering a collaborative, inclusive team culture focused on continuous improvement.

The Opportunity

In this role, you will lead metabolomics research initiatives focused on developing and optimizing cell culture media for a diverse portfolio of cell therapy products. You will provide scientific and strategic guidance to establish highly-productive platform processes while serving as the primary technical expert and thought leader in cell therapy media development. Additional responsibilities include:

  • Designing and developing chemically-defined cell culture media platforms tailored to meet the unique needs of T cell therapies, stem cell therapies, and other cell-based products

  • Applying advanced metabolomics tools, computational methods, and -omics technologies to deeply understand cell metabolism and drive continuous improvement in cell culture performance

  • Leading technology transfer initiatives and collaborate with manufacturing operations to translate laboratory innovations into scalable, robust processes

  • Providing technical leadership and strategic guidance to process development teams, media preparation operations, and supply chain partners to resolve complex challenges and optimize raw material selection

  • Mentoring and developing scientific staff within the Cell Therapy Process Development group, fostering a culture of technical excellence, lean thinking, and continuous improvement

  • Interfacing effectively across multiple internal stakeholder groups (Analytical Development, Research, Manufacturing, Quality) and external collaborators to align priorities and drive impactful outcomes

  • Establishing thought leadership through peer-reviewed publications, conference presentations, and participation in industry discussions on metabolomics and cell therapy manufacturing

This position may be based out of South San Francisco or San Diego, CA.

Who You Are
The successful candidate will have an established track record for strong technical leadership in metabolomics research and/or cell culture media development.

  • Advanced degree and extensive experience: PhD in biological sciences, chemical engineering, or related discipline with 5+ years of relevant research and development experience in metabolomics and/or cell culture media development

  • Strategic technical leadership: Proven track record of leading complex technical projects from conception to completion with strong organizational skills and scientific rigor; demonstrated ability to translate research insights into practical manufacturing solutions

  • Team development and inclusive leadership: Demonstrated success building, managing, and developing highly productive technical teams with an emphasis on creating an inclusive environment that values diverse perspectives and fosters collaboration

  • Matrixed stakeholder management: Proven ability to build and maintain strong relationships with cross-functional partners, customers, and collaborators; excellent skills in influencing, communication, and working effectively across organizational boundaries in complex matrixed environments

  • Thought leadership and communication: Established track record of excellent verbal and written communication demonstrated through peer-reviewed publications, conference presentations, and ability to articulate complex scientific concepts to audiences at all levels

The expected salary range for this position based on the primary location of California is $143,290 - $266,110. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at this link.

Relocation benefits are available for this position.

#LI-CA1

#ptcareers

#cellandgenetherapycareers#

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.


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About Genentech

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A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

Industry

Scientific research and development services

Company size

10,000+ Employees

Headquarters location

South San Francisco, CA, US

Year founded

1976

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