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Cell Line Development Scientist Jobs in Colorado

DHA

Clinical Laboratory Scientist

Colorado Springs, CO · On-site

... or teaching, test development, or medical research program experience that provided an ... Related fields include physiology, anatomy, molecular biology, cell biology, embryology, pathology ...

Actalent

Sales Development Representative

Denver, CO · On-site

$65K/yr

Building trusted relationships with our network of engineering and sciences companies under our ... Monthly car allowance ($425/month) and monthly cell allowance ($100/month) after hourly paid ...

Actalent

Sales Development Representative

Denver, CO · On-site

$343K/yr

Building trusted relationships with our network of engineering and sciences companies under our ... Monthly car allowance ($425/month) and monthly cell allowance ($100/month) after hourly paid ...

Actalent

Sales Development Representative

Denver, CO · On-site

$343K/yr

Building trusted relationships with our network of engineering and sciences companies under our ... Monthly car allowance ($425/month) and monthly cell allowance ($100/month) after hourly paid ...

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Cell Line Development Scientist information

What does a cell line development scientist do?

A Cell Line Development Scientist is responsible for creating and optimizing cell lines used in the production of biopharmaceuticals, such as therapeutic proteins and monoclonal antibodies. Their work involves selecting, engineering, and characterizing cell lines to ensure high productivity, stability, and quality of the desired product. They use advanced techniques in molecular biology, cell culture, and genetic engineering to achieve these goals. Additionally, they document and analyze data, comply with regulatory standards, and collaborate with other departments to support drug development processes.

What are the key skills and qualifications needed to thrive as a cell line development scientist, and why are they important?

To thrive as a Cell Line Development Scientist, you need expertise in molecular and cell biology, mammalian cell culture, and a relevant life sciences degree (often a PhD or MSc). Experience with cloning, gene editing tools (like CRISPR), bioreactors, and data analysis software such as FlowJo or JMP is typically required. Strong problem-solving abilities, attention to detail, and effective teamwork and communication skills distinguish top performers in this role. These competencies are crucial for developing high-quality cell lines efficiently, ensuring robust research outcomes and supporting biopharmaceutical production.

What are some common challenges faced by cell line development scientists during the cell line selection process?

Cell Line Development Scientists often encounter challenges such as ensuring high productivity and stability of the selected cell line, dealing with genetic drift over multiple passages, and minimizing variability in protein expression. Achieving regulatory compliance and thorough documentation is also critical, as processes must be traceable and reproducible. Collaboration with upstream and downstream process teams is essential to address issues early and optimize cell lines for large-scale manufacturing requirements.

What is the difference between Cell Line Development Scientist vs Research Associate in Biotech?

AspectCell Line Development ScientistResearch Associate in Biotech
Required CredentialsBachelor's/Master's in Life Sciences, PhD often preferredBachelor's or Master's in related field
Work EnvironmentLaboratories focused on cell line creation and optimizationGeneral biotech or research labs, supporting various projects
Employer & Industry UsageBiotech and pharmaceutical companies, research institutionsBiotech firms, research organizations, academic labs
Common Search & ComparisonCell Line Development Scientist vs Research Associate in Biotech

The main difference is that a Cell Line Development Scientist specializes in creating and optimizing cell lines for production, requiring more advanced skills and experience. In contrast, a Research Associate in Biotech typically supports broader research activities with less focus on cell line development. Both roles are essential in biotech research but differ in scope and expertise.

What are popular job titles related to Cell Line Development Scientist jobs in Colorado?

For Cell Line Development Scientist jobs in Colorado, the most frequently searched job titles are:

What job categories do people searching Cell Line Development Scientist jobs in Colorado look for?

The top searched job categories for Cell Line Development Scientist jobs in Colorado are:

What cities in Colorado are hiring for Cell Line Development Scientist jobs?

Cities in Colorado with the most Cell Line Development Scientist job openings:

Cell Line Development Scientist jobs near you
Infographic showing various Cell Line Development Scientist job openings in Colorado as of August 2026, with employment types broken down into 1% As Needed, 81% Full Time, 15% Part Time, and 3% Contract. Highlights an 87% Physical, 3% Hybrid, and 10% Remote job distribution.

Senior Manufacturing Development Engineer

Denver, CO • On-site

Xcimer Energy
See more jobs at Xcimer Energyexternal

$93K - $128K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 18 days ago

Job description

Xcimer Energy leverages decades of research on Inertial Fusion Energy (IFE) combined with groundbreaking new laser architecture. Our mission is to deploy fusion power plants to meet global decarbonization goals as fast as possible. Xcimer has assembled a team of leaders in tough tech, fusion science, and manufacturing with a track record of rapid execution. Supportedby leading investors, Xcimer is uniquely positioned to deliver limitless, clean, fusion power to combat climate change.Join us in powering a better world with inertial fusion! 
 
This is a full-time, onsite role based at our headquarters in Denver, CO.

As a Senior Manufacturing Development Engineer, you will be responsible for developing automated equipment and manufacturing processes that enable reliable, repeatable production at increasing volumes. You will take ownership of automated manufacturing projects from concept through deployment, working closely with mechanical, electrical, controls, manufacturing, quality, facilities, and systems engineering partners. This role requires a hands-on engineer who is comfortable moving between design, prototyping, implementation, and troubleshooting in a fast-moving development environment.

This position offers the opportunity to significantly influence manufacturing capability, throughput, and system reliability across multiple hardware platforms critical to fusion energy development.

Responsibilities

Develop Advanced Automated Manufacturing Equipment: Lead the design and implementation of automated manufacturing systems incorporating industrial robotics, motion systems, sensing, and vision technologies. Define system architectures that prioritize reliability, scalability, and maintainability.

Controls and System Integration: Support controls engineers, who will develop and integrate electrical and controls systems using industrial PLCs, standard communication protocols, and HMI platforms. Support data acquisition and performance monitoring to evaluate and improve system behavior. Work with controls engineers to integrate industrial robotic systems to improve consistency, precision, and production efficiency within automated manufacturing cells.

Mechanical Design and DFM Support: Design mechanical components and assemblies using 3D CAD and GD&T principles. Generate detailed fabrication drawings and provide design-for-manufacturing feedback to improve automation performance and robustness.

Risk and Failure Analysis: Conduct product and process failure analyses, including DFMEA and PFMEA, to identify risks, implement mitigations, and support high system uptime.

Project and Program Ownership: Plan and execute multiple projects simultaneously by setting milestones, tracking progress, managing risks, and coordinating cross-functional resources. Support the development of internal processes that enable predictable delivery.

Manufacturing Process Optimization: Evaluate and improve automated manufacturing workflows by analyzing cycle times, material flow, automation ROI, and work-in-process buffering to support consistent production output. 

Technical Documentation and Handover: Create comprehensive documentation including electrical and pneumatic schematics, bills of materials, maintenance documentation, spare parts lists, and troubleshooting guides to support long-term operation.

Safety and Regulatory Compliance: Collaborate with EHS stakeholders to perform risk assessments, define personal safety requirements, and integrate appropriate guarding.

Supplier and Integrator Management: Work with procurement and external vendors to develop RFQs, define technical specifications, manage build and installation phases, and lead factory and site acceptance testing for robots, cobots, palletizers, and other actuated parts of the production line.  Support and coordinate with controls engineers who will own controls hardware definition and procurement.

Qualifications
  • Education: Bachelor's or Master's degree in Mechanical Engineering, Electrical Engineering, Robotics Engineering, or equivalent practical experience
  • Experience: 5+ years of experience in production line development 
  • Demonstrated experience integrating industrial robotic systems
  • Strong mechanical design capability using SolidWorks, including GD&T and drawing release for automated equipment
  • Experience delivering manufacturing robotics or capital equipment projects from concept through commissioning, with proficiency using tools such as Jira or equivalent project tracking systems
  • Background in manufacturing optimization using Lean principles, Six Sigma tools, and structured problem-solving methodologies 
  • Experience integrating machine vision systems, sensors, and closed-loop feedback for precision automation
  • Clear written and verbal communication skills, with the ability to develop technical specifications and collaborate effectively across disciplines
  • Must be a U.S. citizen or national, U.S. permanent resident (current Green Card holder), or lawfully admitted into the U.S. as a refugee of granted asylum 
$141,000 - $150,000 a year
Candidates may be considered for other positions at Xcimer Energy, and our actual base salary will be determined on an individual basis and may vary based on job-related knowledge and skills, education, and experience. The range is published in accordance with Colorado Equal Pay for Equal Work Act and California Equal Pay Act.
Equal Employment Opportunity
Xcimer Energy is proud to be an Equal Opportunity/Affirmative Action Employer and is committed to attracting, retaining, and developing a highly qualified, diverse, and dedicated work force. Xcimer Energy hires and promotes people on the basis of their qualifications, performance, and abilities. We support the establishment and maintenance of a workplace that fosters trust, equality, and teamwork, in which all employees recognize and appreciate the diversity of individual team members. We provide all qualified applicants for employment and employees with equal opportunities for hire, promotion, and other terms and conditions of employment, regardless of their race, color, religion, gender, sexual orientation, gender identity, national origin/ethnicity, age, physical or mental disability, genetic factors, military/veteran status, or any other status or characteristic protected by federal, state, and/or local law. Xcimer Energy will consider for employment qualified applicants with criminal histories in a manner consistent with applicable federal, state, and local laws. For more information on "EEO Is the Law," please see here and here.
 
Benefits
Benefits Employee Benefits include: Medical, dental, vision, basic and supplemental life insurance, paid parental leave (must be employed at time of birth or adoption), short and long-term disability, 401(k) with a company match of up to 6%. Paid Time Off: 15 days per year based on weekly scheduled hours, 10 paid sick leave, and 13 company-paid holidays for all regular employees (including part-time), fixed-term, and interns. Equity will be granted to eligible employees. Equity is designed to allow employees to share in company results and success.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
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