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Analytical Method Development Scientist Jobs in Colorado

Cascade Bio

Process Development Scientist

Denver, CO · On-site

$110K - $150K/yr

Evaluate and implement new equipment and process analytical technology solutions * Lead and grow a small process development team over time, mentoring junior scientists while maintaining a technical ...

Cascade Bio

Process Development Scientist

Denver, CO · On-site

$110K - $150K/yr

Evaluate and implement new equipment and process analytical technology solutions * Lead and grow a small process development team over time, mentoring junior scientists while maintaining a technical ...

Carbon, Inc.

Analytical Chemistry Lead

Brighton, CO · On-site

$130 - $150/hr

... science and real world impact. We are building a diverse, collaborative, and driven team of ... method development, and deployment of software and digital architectures to serve these purposes.

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How much do analytical method development scientist jobs pay per hour?

As of Sep 6, 2026, the average hourly pay for analytical method development scientist in Colorado is $44.24, according to ZipRecruiter salary data. Most workers in this role earn between $33.12 and $51.06 per hour, depending on experience, location, and employer.

What does an analytical method development scientist do?

An Analytical Method Development Scientist is responsible for designing, developing, and validating analytical methods used to test and analyze chemical compounds, pharmaceuticals, or other materials. They ensure that the methods are accurate, reliable, and compliant with regulatory standards. This role involves working with advanced laboratory instruments, troubleshooting analytical issues, and documenting procedures for use in research, quality control, or manufacturing environments.

What are the key skills and qualifications needed to thrive as an analytical method development scientist?

To thrive as an Analytical Method Development Scientist, a strong background in chemistry, analytical techniques, and method validation—often supported by a relevant degree in chemistry or pharmaceutical sciences—is essential. Familiarity with laboratory instrumentation such as HPLC, GC, MS, and software for data analysis, as well as knowledge of regulatory guidelines like ICH and FDA, is typically required. Attention to detail, problem-solving abilities, and effective communication are vital soft skills for success in this role. These skills ensure reliable method development, regulatory compliance, and effective collaboration within multidisciplinary scientific teams.

What are the typical challenges faced by an analytical method development scientist when transferring methods to quality control or manufacturing teams?

One common challenge for Analytical Method Development Scientists is ensuring that newly developed analytical methods are robust and reproducible when transferred to quality control or manufacturing teams. Differences in equipment, sample matrices, or operator technique can impact results, so thorough method validation and clear documentation are essential. Scientists often work closely with cross-functional teams to provide training, troubleshoot issues, and adapt protocols as needed. Successfully managing these transitions helps maintain product quality and regulatory compliance.

What is the difference between Analytical Method Development Scientist vs Analytical Chemist?

AspectAnalytical Method Development ScientistAnalytical Chemist
Primary FocusDeveloping and validating new analytical methodsPerforming routine analysis and testing
Work EnvironmentResearch labs, R&D departmentsQuality control labs, manufacturing facilities
CredentialsBachelor's or Master's in Chemistry or related field; experience in method developmentBachelor's degree in Chemistry or related field; experience in analytical testing

While both roles involve analytical testing, the Analytical Method Development Scientist primarily focuses on creating and validating new analytical methods, often in research settings. In contrast, the Analytical Chemist typically performs routine testing to ensure product quality in manufacturing or quality control labs.

What are popular job titles related to Analytical Method Development Scientist jobs in Colorado?

For Analytical Method Development Scientist jobs in Colorado, the most frequently searched job titles are:

What job categories do people searching Analytical Method Development Scientist jobs in Colorado look for?

The top searched job categories for Analytical Method Development Scientist jobs in Colorado are:

Analytical Method Development Scientist jobs near you
Infographic showing various Analytical Method Development Scientist job openings in Colorado as of August 2026, with employment types broken down into 1% As Needed, 78% Full Time, 19% Part Time, and 2% Contract. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution, with an average salary of $92,028 per year, or $44.2 per hour.

Chemist - R&D Gas Analysis - Longmont, CO

Matheson Tri-Gas, Inc.

Longmont, CO • On-site

$120K - $130K/yr

Full-time

Re-posted 11 days ago

Matheson rating

8.0

Company rating: 8.0 out of 10

Based on 47 frontline employees who took The Breakroom Quiz

33rd of 87 rated oil and gas companies

Job description

Role Overview
Nippon Sanso Matheson is looking for an experienced Analytical Method Development Chemist to drive the development and implementation of industry standards and novel test methods for the Electronics/Specialty Gas Division Analytical Laboratory. In addition, this position may require management of analytical chemists in production and R&D. This analytical laboratory supports routine and non-routine analytical testing for quality, R&D, and other business units within Matheson. Metals analysis and gas phase analysis at ultra-trace levels is routinely conducted and new methods and combination of methods will be developed to meet increasing demands from customers. Direct management of analytical resources along with development of analytical programs are a requirement of this position.
Responsibilities
  • Develop new analytical methods in specialty and electronic gases and mixture of such gases.
  • Combine analytical techniques to increase sensitivity and selectivity of the analyte species to be measured.
  • Ensure developed methods meet all required customer, safety, and industry standards.

• Provide customer facing support for new and existing analytical methods and data in support of existing and new products from Matheson.
• Collaborate with Matheson partners, customers, and technical consortia in support of new product development by implementing new and novel analytical methods and instrumentation.
• Manage and resolve new customer complaints and requests for assistance as it pertains to analytical methods, data and inquires.
  • Support the selection, purchasing, installation of analytical instrumentation and other sample preparation associated equipment
  • Implement method improvements over time based on learnings from routine analysis, best practices, test failures, and customer requests
  • Develop and validate test methods to meet accuracy, precision, robustness, specificity, linearity, detection limit, and any other requirements
  • Ability to troubleshoot complex instruments and methods in an organized and well documented manner including assisting with developing preventative maintenance practices
  • Lead cross-functional discussions to define test method performance criteria and business requirements
  • Provide critical technical support to a team managing the day-to-day operations of a high-through put analytical laboratory
  • Serve as a leader in maintaining and improving safety in the lab and in the work process
  • Author test methods documents and associated lab standard operating procedures to be consistently performed by lab technicians of various technical backgrounds and capabilities
  • Train and certify lab staff to perform to associated testing practices to method requirements
  • Support lab management in the implementation of best laboratory practices for incoming, process, and final product testing to provide timely and consistent testing services for internal and external customers

Knowledge and Skills
  • Previous hands-on experience with, ICP-MS, IC, GC, GC/MS, FTIR, CRDS, XRF and/or other analytical/metrological testing instrumentation
  • Knowledge of standard industry practices for method development, transfer, and validation
  • Experience and good skills in technical writing and documentation with attention to detail in documents being written.
  • Knowledge of Good Laboratory Practice (GLP) principles
  • Previous technical writing experience, including authoring test method documentation
  • Ability to remain positive and professional in a high-pressure environment
  • Strong analytical problem solving, organizational, and documentation skills

Education and Experience
  • Bachelors of Science (BS) in Chemistry or related scientific field with 10+ years or advanced degree such and (MS) or (PhD) with 5+ years of analytical or metrological method development experience
  • Demonstrated ability to develop test methods utilizing multiple pieces of instrumentation listed in the Knowledge and Skills section
  • Demonstrated ability to combine instruments to lower detection limits or increase selectivity of the instruments.
  • Demonstrated ability to learn new techniques and solve complex analytical problems
  • Demonstrated ability to work under pressure while pushing projects to completion with strict time lines
  • Demonstrated ability to independently manage multiple projects of various priorities
  • Experience with method development, validation, and transfer in a quality environment
  • Experience with a wide range of instrumentation software, Microsoft Office Suite, Minitab, and other statistical software
  • Experience with Laboratory Information Management software systems (LIMS)

Compensation: $120-130k DOE
Nippon Sanso Matheson is an Equal Opportunity Employer that complies with the laws and regulations set forth under EEOC.. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status. EOE AA M/F/VET/Disability

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