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Car T Cell Jobs (NOW HIRING)

Management of post CAR-T cell therapy patients Responsibilities * Perform bone marrow biopsies * Manage post autologous stem cell transplant patients * Manage post CAR-T cell therapy patients ...

The ideal candidate will bring deep expertise in CAR-T biology, T-cell functional assays, and therapeutic development. The role includes designing CAR constructs, executing advanced cell-based assays ...

The ideal candidate will bring deep expertise in CAR-T biology, T-cell functional assays, and therapeutic development. The role includes designing CAR constructs, executing advanced cell-based assays ...

Senior Scientist Bispecific & T-Cell Engager

San Jose, CA ยท On-site

$107K - $146K/yr

OGAP is used to identify novel, highly tumor specific antigens for novel first-in-class ADC, T-cell Engager (TCE) and Chimeric Antigen Receptor (CAR-T) targets. Our lead asset, OBT076, is an Antibody ...

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Car T Cell information

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$10

$17

$24

How much do car t cell jobs pay per hour?

As of Aug 19, 2026, the average hourly pay for car t cell in the United States is $17.41, according to ZipRecruiter salary data. Most workers in this role earn between $14.90 and $19.23 per hour, depending on experience, location, and employer.

What are CAR T cells?

CAR T cells are a type of immunotherapy where a patient's own T cells are genetically modified to express a chimeric antigen receptor (CAR) that targets specific proteins found on cancer cells. These engineered T cells are then infused back into the patient to help the immune system recognize and attack cancer cells more effectively. CAR T cell therapy has been especially effective in treating certain blood cancers such as leukemia and lymphoma. The process involves collecting T cells from the patient, modifying them in a laboratory, and then returning them to the patient after conditioning chemotherapy. While it offers promising results, it can also cause serious side effects, so patients are monitored closely during and after treatment.

What are the key skills and qualifications needed to thrive as a CAR T cell therapy specialist?

To thrive as a CAR T Cell Therapy Specialist, you need a background in cellular therapy, hematology/oncology, and a relevant healthcare degree such as nursing, pharmacy, or medicine. Familiarity with CAR T cell therapy protocols, apheresis equipment, and certification in chemotherapy administration are commonly required. Strong attention to detail, teamwork, and communication skills help ensure safe and effective patient management. These competencies are vital for delivering complex, cutting-edge treatments while ensuring patient safety and adherence to rigorous clinical standards.

What are some of the unique challenges faced by CAR T cell therapy specialists in a clinical setting?

CAR T cell therapy specialists often encounter challenges related to managing severe and rapid-onset side effects, such as cytokine release syndrome and neurotoxicity, which require quick and coordinated responses with multidisciplinary teams. The role also involves staying updated with rapidly evolving protocols and regulatory requirements due to the novel nature of this treatment. Specialists frequently collaborate with hematologists, oncologists, pharmacists, and research coordinators to ensure patient safety and the success of clinical trials and therapies.

What is the difference between Car T Cell vs CAR T Cell Specialist?

AspectCar T CellCAR T Cell Specialist
Required CredentialsBiotech or medical degree, laboratory trainingBiotech or medical degree, specialized training in CAR T therapies
Work EnvironmentLaboratories, research facilitiesClinical settings, hospitals, research labs
Industry UsageResearch and development of T cell therapiesImplementation and management of CAR T cell treatments in patients

Car T Cell roles focus on research and development of T cell therapies, while CAR T Cell Specialists are involved in clinical application and patient care. Both require similar educational backgrounds but differ in work environment and responsibilities.

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What cities are hiring for Car T Cell jobs?

Cities with the most Car T Cell job openings:

What states have the most Car T Cell jobs?

States with the most job openings for Car T Cell jobs include:

Infographic showing various Car T Cell job openings in the United States as of August 2026, with employment types broken down into 37% Full Time, 59% Part Time, and 4% Contract. Highlights an 99% Physical, and 1% Remote job distribution, with an average salary of $36,219 per year, or $17.4 per hour.

Senior Scientist Bispecific & T-Cell Engager

MOST

San Jose, CA โ€ข On-site

$140K - $160K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 12 days ago


Job description

About Oxford Biotherapeutics:
Oxford Biotherapeutics is a clinical-stage biotechnology company focusing on the development of antibody therapeutics for the treatment of cancer. OBT's OGAP-verifyยฎ platform is the world's largest, cancer specific, membrane protein library, directly measuring plasma membrane protein expression in patient tumors. OGAP is used to identify novel, highly tumor specific antigens for novel first-in-class ADC, T-cell Engager (TCE) and Chimeric Antigen Receptor (CAR-T) targets. Our lead asset, OBT076, is an Antibody Drug Conjugate (ADC) in Phase 1b clinical development. Our clinical and pre-clinical pipeline of novel biologics is balanced between internal programs, focused on ADCs and checkpoint regulators, and externally partnered programs with key innovators in oncology such as Roche, GSK and Zymeworks.
Job Description
We are seeking a highly motivated and intellectually curious Senior Scientist to join our discovery research organization. This individual will play a central role in advancing T-cell engagers by generating high
quality, decision
driving data from early discovery through IND. The role blends hands
on experimental expertise with scientific leadership, assay innovation, and cross-
functional collaboration.
Responsibilities will include, but are not limited to, the following:
Scientific Leadership & Program Execution
  • Design, execute, and lead in vitro functional studies supporting target discovery, validation, lead selection and optimization, and preclinical development of T-cell engagers.
  • Develop, optimize, and run T-cell functional assays to inform potency, selectivity, and safety. (e.g., cytotoxicity, cytokine release, activation, immune profiling, reporter assays).
  • Design and run co-culture assays to evaluate T-cell-mediated tumor cell killing in response to T-cell engagers.
  • Design and execute primary human T-cell assays, including activation, cytokine release, T-cell exhaustion, mixed lymphocyte reaction assays and proliferation. Generate and interpret complex datasets with a strong emphasis on scientific rigor, reproducibility, and data quality.
  • Build decision-focused data packages and communicate clear scientific conclusions and recommendations to project teams, management, and external collaborators.

Assay Development & Technical Expertise
  • Develop and execute multiparameter flow cytometry, including activation and intracellular cytokine staining.
  • Design and perform real-time cytotoxicity assays (e.g., IncuCyte, eSight) and other functional readouts relevant to T-cell engager activity.
  • Characterize T-cell engagers using cell-based functional assays, including cytokine release and cytotoxicity.
  • Understand various TCE formats and improve tumor-specific killing efficacy.

Collaboration & Cross-Functional Engagement
  • Collaborate closely across teams to evaluate and optimize T-cell engager molecules.
  • Coordinate with external collaborators and CROs to deliver high quality, timely data.
  • Proactively identify project risks, propose mitigation strategies, and communicate progress and challenges clearly to stakeholders.

Innovation & External Awareness
  • Monitor the scientific literature and competitive landscape relevant to T-cell engagers and emerging immune redirecting modalities.
  • Propose innovative experimental approaches to accelerate early-stage discovery.
  • Serve as an internal subject matter expert in T cell immunobiology and immune redirecting therapies.
  • Monitor the scientific literature and competitive landscape relevant to OGAP-selected targets.

Team Leadership & Culture
  • Foster a culture of scientific rigor, learning, transparency, accountability, and inclusion.
  • Act as a scientific thought leader within the research organization.

Compliance & Documentation
  • Adhere to OBT's Quality Management System (QMS), including SOPs, documentation standards, electronic lab notebooks, and required training.
  • Support audit readiness and contribute to continuous improvement of laboratory systems and workflows.

Please note the roles and responsibilities for the position include but are not limited to the above
Required Qualifications and Skills:
  • PhD with 4-6 years of relevant post-PhD experience, or
  • MS with 8-12 years of relevant industry experience demonstrating increasing scientific independence and technical leadership
  • Basic understanding of antibody therapeutics development
  • Hands-on experience working with T-cell engagers and/or bispecific antibody formats.
  • Strong hands-on experience with core immunology techniques, including:
  • PBMC and primary human T-cell isolation, culture, and functional assays
  • Multiparameter flow cytometry and panel design
  • Intracellular cytokine staining & other flow-based assays
  • Cell-based reporter assays
  • Demonstrated ability to design, analyze, and interpret complex datasets and translate results into clear scientific conclusions.
  • Strong written and verbal communication skills, with the ability to present data to multidisciplinary audiences.
  • Combines a humble, team-oriented mindset with the ability to form and voice clear, independent viewpoints.

Preferred Qualifications and Skills:
  • Experience contributing to biologics discovery programs from early discovery through lead optimization and/or preclinical development.
  • Track record of scientific impact demonstrated through publications, patents, presentations, or program advancement.
  • Experience with both traditional and homogeneous ELISA-derived platforms, including AlphaLISA and/or multiplex systems such as Luminex.

One of our top priorities is to maintain the health and wellbeing of our employees and their families. To achieve this goal, we offer comprehensive benefits.
Benefits Offered:
  • Medical, dental and vision insurance for employee and dependents
  • FSA (Flexible Spending Account)
  • STD, LTD, Basic Life and AD&D Insurance, Supplemental Life
  • 401(k) Plan
  • 120 hours of Paid Time Off
  • 5 sick days per year
  • 11 holidays
  • Employee Referral Bonus Program
  • Annual bonus program
  • New hire stock options

Equal Opportunities Statement
OBT is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status, and veteran status. All qualified applicants will receive consideration for employment. One of our top priorities is to maintain the health and wellbeing of our employees and their families. To achieve this goal, we offer comprehensive benefits