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Biotech Software Engineer Jobs in Chicago, IL (NOW HIRING)

Tempus

Senior Quality Engineer

Chicago, IL · On-site

... Software Engineering, Informatics, Biomedical, or relevant engineering disciplines. * 5+ years experience in FDA regulated domain (e.g. medical device, pharma, biotech) * 3+ years experience in ...

Tempus

Senior Quality Engineer

Chicago, IL · On-site +1

... Software Engineering, Informatics, Biomedical, or relevant engineering disciplines. * 5+ years experience in FDA regulated domain (e.g. medical device, pharma, biotech) * 3+ years experience in ...

BiomeSense

Senior Bioinformatics Engineer

Chicago, IL · On-site

$125K - $200K/yr

Position Help build our MetaBiome platform, a software solution for collecting, curating ... biotech start-up ideal) * Proficiency in Python & JavaScript & experience in production-quality ...

IMA Automation USA Inc

Service Controls Engineer

Elgin, IL · On-site

$83K - $107K/yr

Troubleshoot hardware and software for automated equipment as well as program development while ... Technical understanding of pharmaceutical / biotechnology unit operations a plus. * Fundamental ...

Until

Head of Legal

Mundelein, IL

$250K - $300K/yr

Own Until's IP strategy across hardware, software, chemistry, and biology. * Coordinate proactive ... Partner closely with R&D and engineering to ensure technical iterations are reflected in IP filings ...

bioMerieux

QC Technician II - Accellix.

Lombard, IL

$23.50 - $32.60/hr

Partner with Quality, Manufacturing, Engineering, and other cross-functional teams to support ... Exposure to data analysis software or laboratory data systems. * Experience in biotechnology ...

Biomerieux

QC Technician II - Accellix.

Lombard, IL · On-site

$23.50 - $32.60/hr

Partner with Quality, Manufacturing, Engineering, and other cross-functional teams to support ... Exposure to data analysis software or laboratory data systems. * Experience in biotechnology ...

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All JobsBiotech Software Engineer JobsBiotech Software Engineer Jobs in Chicago, IL

Biotech Software Engineer information

See Chicago, IL salary details

$65.4K

$152K

$211.7K

How much do biotech software engineer jobs pay per year?

As of Jul 20, 2026, the average yearly pay for biotech software engineer in Chicago, IL is $151,971.00, according to ZipRecruiter salary data. Most workers in this role earn between $123,600.00 and $178,200.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in the Biotech Software Engineer position, and why are they important?

To thrive as a Biotech Software Engineer, you need a solid background in computer science or software engineering, coupled with an understanding of biology, genetics, or related life sciences. Familiarity with programming languages such as Python or Java, experience using bioinformatics tools (like BLAST or Bioconductor), and, in some settings, knowledge of regulatory standards are highly valuable. Strong problem-solving abilities, effective communication, and the ability to work well in interdisciplinary teams distinguish top performers in this field. These skills are crucial for building reliable software solutions that support scientific discovery and innovation in biotechnology organizations.

What engineers make $500,000?

Senior biotech software engineers with extensive experience, specialized skills in data analysis, machine learning, or bioinformatics, and often working in leadership roles or at large biotech firms can earn $500,000 or more annually. High compensation may also include bonuses, stock options, or profit sharing, especially in competitive or rapidly growing companies.

What are some typical projects or daily tasks for a Biotech Software Engineer?

As a Biotech Software Engineer, you'll often develop and maintain software tools for analyzing biological data, automate laboratory workflows, or create user-friendly interfaces for scientific researchers. Your daily tasks might include writing code, troubleshooting algorithms, reviewing scientific data, and collaborating closely with biologists, data scientists, and laboratory technicians. Depending on the company, you may be involved in developing cloud-based platforms, integrating new laboratory hardware, or ensuring software compliance with industry regulations. This dynamic and collaborative environment means your work directly impacts ongoing research and helps accelerate scientific discoveries in the biotech sector.

Will AI replace biotechnologists?

Biotech software engineers and biotechnologists perform complementary roles; AI can automate certain tasks like data analysis and modeling but is unlikely to fully replace the expertise, creativity, and decision-making skills required in biotechnology. Human oversight remains essential for experimental design, interpretation, and ethical considerations in the field.

What is a biotech software engineer?

A biotech software engineer develops software applications and tools to support biological research, healthcare, and pharmaceutical development. They often work with data analysis, automation, and laboratory systems, requiring skills in programming, bioinformatics, and understanding of biological processes.

What is a Biotech Software Engineer job?

A Biotech Software Engineer develops software solutions for the biotechnology industry, enabling research, data analysis, and automation in fields like genomics, bioinformatics, and drug discovery. They work with scientists to design algorithms, manage biological data, and create applications that support experiments and workflows. This role requires expertise in programming, cloud computing, and biological sciences to bridge the gap between technology and life sciences.

Can you make $500,000 as a software engineer?

Biotech software engineers typically earn between $80,000 and $150,000 annually, with higher salaries possible for senior roles or those with specialized skills like data analysis or machine learning. Reaching a $500,000 salary usually requires extensive experience, leadership positions, or working in high-paying industries or companies. Such compensation levels are uncommon for standard biotech software engineering roles.
What are the most commonly searched types of Biotech Software Engineer jobs in Chicago, IL? The most popular types of Biotech Software Engineer jobs in Chicago, IL are:
What are popular job titles related to Biotech Software Engineer jobs in Chicago, IL? For Biotech Software Engineer jobs in Chicago, IL, the most frequently searched job titles are:
What job categories do people searching Biotech Software Engineer jobs in Chicago, IL look for? The top searched job categories for Biotech Software Engineer jobs in Chicago, IL are:
Biotech Software Engineer jobs near you
Infographic showing various Biotech Software Engineer job openings in Chicago, IL as of July 2026, with employment types broken down into 83% Full Time, 6% Temporary, and 11% Contract. Highlights an 94% In-person, and 6% Remote job distribution, with an average salary of $151,971 per year, or $73.1 per hour.
Senior Quality Engineer

Senior Quality Engineer

Tempus

Chicago, IL • On-site

Full-time

Re-posted 16 days ago

Job description

Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
PLEASE NOTE: This is a hybrid role requiring three days a week in the office. Candidates can be based out of our Chicago (Headquarters), New York, or Redwood City locations.
As a Senior Quality Engineer, you will:
  • Lead verification, validation and maintenance of host systems supporting Tempus Medical Device(s).
  • Lead risk assessments to determine testing strategies.
  • Be involved in the medical device software design controls activities, in accordance with the FDA Quality System Regulation, ISO 13485, GAMP5, Computer System Validation (CSV) standards and FDA guidance, other applicable regulatory requirements, as well as best practices in the software industry.
  • Lead computer system validation (CSV) activities of Tempus AI applications, software tools, and computer systems against user, functional and regulatory requirements.

Responsibilities:
  • Support regulatory compliance of the host system operating with Tempus Medical Device(s).
  • Develop and maintain CSV policies, procedures, templates and work instructions.
  • Lead risk-based approach to host / computer system validation (HSV/CSV), SDLC and design controls activities.
  • Perform validation, re-validation and change controls of various AI, SaaS, and Tempus in-house developed software.
  • Author and review software validation deliverables, including Risk Assessments, Validation Plans, Requirements (URS), Validation Protocols (IQ, OQ, PQ), UAT (User Acceptance Test), and Validation Reports.
  • Collaborate with cross-functional teams in developing test-driven system/functional requirements, defining testing strategies and participating in test execution.
  • Support Change Management and Major Incidents (MI) processes, ensuring organizational compliance and continuous improvement.
  • Provide support to Quality and IT organizations in maintaining compliance to various policies, procedures and activities, including support during internal/external inspections and regulatory and customer audits.
  • Provide CSV guidance, coaching, mentorship, and training to test engineers within the team.

Qualifications
  • BA/B.S. or higher preferred in Computer Science, Software Engineering, Informatics, Biomedical, or relevant engineering disciplines.
  • 5+ years experience in FDA regulated domain (e.g. medical device, pharma, biotech)
  • 3+ years experience in Computer System Validation (CSV).
  • Experience with industry standards and best practices for Medical device software and CSV such as Design Controls, GAMP 5, FDA 21 CFR Part 11, FDA (QSR) FDA 21 CFR 820.30, Medical device software (QMS) ISO 13485:2016, FDA 21 CFR 820, and Software life cycle processes (IEC 62304:2006).
  • Knowledge of quality system principles, practices, and standards for the life science industry.
  • Ability to deliver quality outputs without directions or under minimal supervision.

Chicago Pay Range: $90,000-$130,00
NYC/SF Pay Range: $100,000-$150,000
The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
Additionally, for remote roles open to individuals in unincorporated Los Angeles - including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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