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Bioreactor Jobs in New York (NOW HIRING)

Jj

Lentivirus Manufacturing Operator

Raritan, NJ · On-site

$18 - $21.50/hr

Perform tasks related to single use bioreactor operations including bioreactor setup, sampling and monitoring, and disassembly. * Work in a team based, cross-functional environment to complete ...

MSD

Biologics Process R&D Senior Scientist

Rahway, NJ

$100K - $127K/yr

Understanding of basic bioreactor principles, mass transfer kinetics * Understanding of cell & molecular biology * Downstream * Sound scientific knowledge of protein properties and purification

MSD

Biologics Process R&D Scientist

Rahway, NJ · On-site

Bioanalytical Techniques, Bioreactor Operation, Cell Culture Process Development, Cross-Functional Teamwork, GMP Compliance, Mammalian Cell Culture, Microbial Fermentation, Optimism, Process ...

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Bioreactor information

What is a bioreactor?

A Bioreactor job typically involves the operation, monitoring, and maintenance of bioreactors used in biopharmaceutical, food, or industrial biotechnology production. Professionals in this role ensure optimal conditions for cell cultures or microbial fermentation processes, adjusting parameters like pH, temperature, and oxygen levels. They also troubleshoot equipment issues, collect and analyze samples, and comply with industry regulations. This role is essential in producing biologics, vaccines, enzymes, and other biotech products.

What does a bioreactor operator do?

A typical day for a Bioreactor Operator or Technician involves preparing and maintaining bioreactor equipment, monitoring culture conditions, recording process data, and troubleshooting any operational issues that arise. You’ll often work closely with quality assurance teams, engineers, and scientists to ensure that production runs smoothly and meets regulatory standards. Routine tasks may include sampling, calibration, cleaning, and adjusting process parameters as needed. This collaborative and dynamic environment allows you to expand your technical skills and play a vital role in the successful production of biopharmaceuticals or other biotech products.

What skills and qualifications are needed to thrive as a bioreactor operator?

To thrive as a Bioreactor Operator or Technician, you need a solid background in biotechnology, microbiology, or chemical engineering, often supported by an associate’s or bachelor’s degree in a related field. Proficiency with bioreactor systems, control software, and quality assurance protocols is crucial, and relevant certifications such as GMP (Good Manufacturing Practice) are highly valued. Attention to detail, problem-solving skills, and strong teamwork abilities set top performers apart in this role. These capabilities ensure safe, efficient, and compliant bioprocessing operations that are vital for producing high-quality biological products.

What are the most commonly searched types of Bioreactor jobs in New York?

The most popular types of Bioreactor jobs in New York are:

What are popular job titles related to Bioreactor jobs in New York?

For Bioreactor jobs in New York, the most frequently searched job titles are:

What job categories do people searching Bioreactor jobs in New York look for?

The top searched job categories for Bioreactor jobs in New York are:

What cities in New York are hiring for Bioreactor jobs?

Cities in New York with the most Bioreactor job openings:

Bioreactor jobs near you
Infographic showing various Bioreactor job openings in New York as of August 2026, with employment types broken down into 84% Full Time, 4% Part Time, 9% Contract, and 3% Nights. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution.

Sr. Scientist, Lentivirus Upstream Processing

Legend Biotech US

Somerset, NJ • Hybrid

$96K - $132K/yr

Full-time

Re-posted 6 days ago

Job description

Legend Biotech is seeking a Sr. Scientist, Lentivirus Upstream Processing as part of the Technical Development team based in Somerset, NJ.

Role Overview

The Senior Scientist, Lentivirus Upstream Process Development, will be a core technical contributor responsible for designing, executing, and optimizing upstream production processes for lentiviral vectors (LVV) within our innovative pipeline. This role focuses on delivering high-quality, high-titer vector products to support LVV generation and other advanced cell therapy programs. The successful candidate will apply technical expertise in upstream processing (USP)-including seed train optimization, mammalian cell culture (HEK293/HEK293T), large-scale transient transfection, and bioreactor scale-up-to ensure processes are robust, scalable, and phase-appropriate for GMP manufacturing. This position demands a blend of hands-on technical mastery and strong analytical thinking to support project timelines while maintaining a patient-focused approach.

Key Responsibilities

  • Design and execute experimental strategies for lentiviral vector upstream production.
  • Perform development and optimization of upstream processes, including seed train expansion, suspension mammalian cell culture (HEK293/HEK293T), plasmid transient transfection optimization, and feed batch/perfusion bioprocessing in stir-tank and rocker bioreactors.
  • Support the establishment and validation of bioreactor scale-up and scale-down models to ensure process comparability and predictability.
  • Support the translation of bench-scale processes to GMP manufacturing, assisting in technology transfer and providing troubleshooting support during clinical production runs.
  • Execute study protocols to define operating parameters, feeding strategies, and performance limits; maintain accurate documentation for USP data.
  • Communicate technical findings, issues, and potential delays to project leads in a timely manner.
  • Collaborate with cross-functional team members, including CMC Project Management and other technical leads, to support project goals.
  • Apply scientific knowledge and technology to optimize vector titer, specific productivity, and quality.
  • Support team activities by providing technical guidance to junior staff, fostering a culture of scientific rigor and continuous improvement.
  • Author and review technical documents, including development reports, SOPs, and relevant sections for regulatory submissions (IND).
  • Work closely with Downstream Process Development and Analytical Development teams to ensure integrated process outcomes.
  • Support tech transfer activities to/from other Legend sites or CDMOs.
  • Ensure compliance with all internal and regulatory requirements.

Requirements

  • Advanced degree (PhD preferred, or MS) in Chemical Engineering, Bioengineering, or a related field.
  • Experience: 5-8 years (PhD) or 8+ years (MS) of experience in process development or manufacturing within a biotech or pharmaceutical setting
  • Hands-on experience in mammalian cell culture (HEK293, HEK293T), seed train expansion, feeding strategy, and transient transfection optimization specifically for viral vectors (Lentivirus preferred).
  • Demonstrated proficiency in developing and implementing bioreactor scale-up and scale-down models.
  • Solid understanding of GMP manufacturing requirements and CMC strategies for early-phase clinical trials.
  • Direct experience with cell and lentiviral vector technologies within the current emerging field.
  • Working knowledge in engineering modeling, mass transfer, and bioprocess optimization.
  • Strong interpersonal and communication skills; ability to maintain focus and collaborate effectively during challenging development timelines.
  • Analytical and creative thinking.
  • Effective troubleshooting skills.
  • Preferred experience in handling large-scale (>50L, e.g., 200L/500L) upstream bioreactor processes.
  • Language(s):
  • English. Mandarin is a plus.

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