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Biological Systems Engineering Jobs in Minnesota

Baxter

Sr. Quality Engineer

Saint Paul, MN · On-site

$89K - $121K/yr

Minimum 3 years of Quality Engineering experience within a regulated medical device, pharmaceutical, biologics, or combination product environment. * Working knowledge of FDA Quality System ...

Bora Pharmaceuticals

Head of Engineering

Maple Grove, MN · On-site

... biologics, and sterile injectable pharmaceutical products. From our world-class sites in North ... Ensure that the automation systems are developed/maintained to meet the current and future needs of ...

Mayo Clinic

Director - AI Digital Biology

Rochester, MN · Hybrid

$204K - $306K/yr

Responsibilities The Director - Artificial Intelligence (AI) leads the engineering and research ... Virtual Cells, biological digital twins, and digital biomarker discovery. Directing a ...

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All JobsBiological Systems Engineering JobsBiological Systems Engineering Jobs in Minnesota

Biological Systems Engineering information

See Minnesota salary details

$30.4K

$41.2K

$54.8K

How much do biological systems engineering jobs pay per year?

As of Aug 17, 2026, the average yearly pay for biological systems engineering in Minnesota is $41,239.00, according to ZipRecruiter salary data. Most workers in this role earn between $36,700.00 and $45,500.00 per year, depending on experience, location, and employer.

What is biological systems engineering?

Biological Systems Engineering is an interdisciplinary field that applies engineering principles to biological and agricultural systems. Professionals in this field work on developing sustainable solutions for food production, environmental protection, bioenergy, and resource management. They integrate biology, chemistry, and engineering to design systems and technologies that improve the efficiency and sustainability of processes involving living organisms. Careers can include work in agriculture, environmental consulting, biotechnology, and renewable energy industries.

What are the key skills and qualifications needed to thrive as a biological systems engineer?

To thrive as a Biological Systems Engineer, you need a solid background in engineering principles, biology, and mathematics, generally supported by a degree in biological systems engineering or a related field. Familiarity with CAD software, modeling tools like MATLAB, and knowledge of relevant industry standards or certifications (such as FE/EIT) is often required. Strong problem-solving, teamwork, and communication skills help professionals excel in multidisciplinary projects and effectively convey complex ideas. These skills and qualifications ensure engineers can develop sustainable solutions to biological and agricultural challenges, bridging the gap between engineering and life sciences.

What are some common interdisciplinary collaborations for biological systems engineers within an organization?

Biological Systems Engineers frequently work alongside professionals from a variety of fields, such as agronomists, environmental scientists, mechanical engineers, and computer scientists. These collaborations often focus on developing sustainable solutions for agricultural production, environmental protection, or bioenergy systems. Working in cross-functional teams helps Biological Systems Engineers address complex real-world challenges, integrate new technologies, and ensure that project outcomes are practical and scalable. Effective communication and teamwork are essential, as projects may involve coordinating fieldwork, data analysis, and system optimization.

What is the difference between Biological Systems Engineering vs Agricultural Engineer?

AspectBiological Systems EngineeringAgricultural Engineer
CredentialsBachelor's in Biological Systems Engineering or related fieldBachelor's in Agricultural Engineering or related field
Work EnvironmentResearch labs, manufacturing, environmental systemsFarms, agricultural facilities, rural settings
Industry UsageBiotech, environmental, healthcare, manufacturingAgriculture, food production, rural infrastructure

Biological Systems Engineering focuses on applying engineering principles to biological systems across various industries, including healthcare and environmental management. Agricultural Engineers primarily work within the agriculture sector, designing systems for farming, irrigation, and food production. While both roles require similar credentials, their work environments and industry applications differ significantly.

Are biological systems engineers well paid?

Biological systems engineers typically earn competitive salaries that vary based on experience, education, and location. Entry-level positions often start around the national average for engineering roles, with experienced professionals earning higher wages, especially in industries like biotechnology, agriculture, and environmental management.

What does a biological systems engineer do?

A biological systems engineer designs and develops processes that integrate biology with engineering principles to improve agricultural, environmental, or healthcare systems. They work with tools like modeling software and laboratory equipment, often requiring knowledge of biology, engineering, and data analysis. Their work may involve research, process optimization, and interdisciplinary collaboration to solve complex biological problems.

What jobs can you get with a biological systems engineering degree?

Biological systems engineering graduates can pursue careers as biological or agricultural engineers, environmental engineers, or process engineers, often working in industries such as agriculture, healthcare, or environmental management. These roles typically require knowledge of biology, engineering principles, and often involve designing systems, managing projects, or improving processes using tools like CAD software and data analysis. Certification or licensing may be required for certain engineering positions.

What are popular job titles related to Biological Systems Engineering jobs in Minnesota?

For Biological Systems Engineering jobs in Minnesota, the most frequently searched job titles are:

What job categories do people searching Biological Systems Engineering jobs in Minnesota look for?

The top searched job categories for Biological Systems Engineering jobs in Minnesota are:

Biological Systems Engineering jobs near you
Infographic showing various Biological Systems Engineering job openings in Minnesota as of August 2026, with employment types broken down into 1% As Needed, 88% Full Time, 7% Part Time, 3% Contract, and 1% Nights. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $41,239 per year, or $19.8 per hour.

Postdoctoral Research Fellow - T Cell Engineering Lab

Mayo Clinic

Rochester, MN

$49K - $67K/yr

Full-time

Medical, Dental, Vision, Retirement

Re-posted 13 days ago

Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 699 frontline employees who took The Breakroom Quiz

128th of 887 rated healthcare providers

Job description

The T Cell Engineering Laboratory (Kenderian Laboratory) at Mayo Clinic is seeking a highly motivated and talented Postdoctoral Research Fellow to lead and contribute to the development of next-generation engineered cell therapies for cancer and immune-mediated diseases. 

Our laboratory is recognized for its work in CAR T cell biology, synthetic and logic-gated cell therapies, mechanisms of resistance and toxicity, and translational immunotherapy, with a strong emphasis on moving discoveries from bench to clinic. The successful candidate will work in a highly collaborative, well-resourced environment with direct access to GMP manufacturing, clinical trials, and multidisciplinary translational teams. 

This position is ideal for individuals aspiring to careers in academic medicine, biotechnology, or translational research leadership. The postdoctoral fellow will have the opportunity to lead independent and collaborative projects in areas including (but not limited to):

  • Design and engineering of next-generation CAR T and other engineered immune cell therapies
  • Synthetic biology approaches (e.g., logic-gated receptors, synNotch, armored CARs)
  • Overcoming tumor immune evasion, antigen loss, exhaustion, and senescence
  • Mechanisms of on-target/off-tumor toxicity and immune-related adverse events
  • Translational studies bridging preclinical models, GMP manufacturing, and early-phase clinical trials
  • Solid and hematologic malignancies, with opportunities for cross-platform innovation

Projects will be tailored to the fellow's expertise and career goals, with strong encouragement and support for first-author high-impact publications and independent funding applications. The laboratory offers a unique translational ecosystem, including:

  • State-of-the-art BSL-2+/cell engineering laboratories
  • Access to GMP cell manufacturing through the Center for Regenerative Biotherapeutics
  • Close interaction with clinician-scientists, immunologists, bioengineers, and industry collaborators

Strong mentoring culture with structured guidance in:

  • Grant writing (NIH K99/R00, foundation awards)
  • Manuscript preparation for top-tier journals
  • Scientific presentation and leadership development
  • Career advancement in academia or industry
Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Required qualifications:

Ph.D., M.D., or M.D./Ph.D. in Immunology, Cancer Biology, Bioengineering, Molecular Biology, or a related field. Strong background in cellular or molecular immunology or cancer biology. Demonstrated productivity with peer-reviewed publications. Excellent written and verbal communication skills. High level of independence, creativity, and scientific rigor.

Preferred qualifications: (not required)

Experience with T cell biology, CAR T cell engineering, or adoptive cell therapy. Expertise in one or more of the following:

  • Viral or non-viral gene delivery
  • Flow cytometry and immune phenotyping
  • CRISPR/Cas9 or genetic engineering
  • In vivo mouse models
  • Synthetic biology platforms
  • Interest in translational or clinically oriented research

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About Mayo Clinic

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Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919

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