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Bioinformatics Software Developer Jobs in California

AllSTEM Connections

Software Developer - II

Pescadero, CA · On-site

$164K - $185K/yr

Bachelor's degree in Computer Science, Software Engineering, Bioinformatics, Data Science, or a related technical discipline. • Experience Baseline: Minimum of 3 to 5 years of relevant professional ...

Worky

Software Quality Engineer II

San Diego, CA · On-site

Summary Bionano is looking for a talented software quality engineer to support our bioinformatic software. Our goal is to produce compelling, robust commercial products that enable our customers to ...

ROSALIND

Bioinformatics Engineer

San Diego, CA · On-site

As a Bioinformatics Engineer, you will develop software for analyzing and visualizing complex biological data while collaborating with Front-End and Cloud Infrastructure Engineering teams.

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Bioinformatics Software Developer information

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How much do bioinformatics software developer jobs pay per hour?

As of Sep 14, 2026, the average hourly pay for bioinformatics software developer in California is $42.23, according to ZipRecruiter salary data. Most workers in this role earn between $41.97 and $42.45 per hour, depending on experience, location, and employer.

What is a bioinformatics software developer?

A Bioinformatics Software Developer designs, implements, and optimizes software tools for analyzing biological data, such as genomic sequences or protein structures. They combine expertise in computer science, bioinformatics, and data science to develop algorithms, databases, and pipelines that support research and clinical applications. These developers often work with researchers to streamline data processing, improve efficiency, and enable new discoveries in the life sciences. Strong programming skills in languages like Python, Java, or R, along with knowledge of bioinformatics frameworks, are essential for this role.

What are the key skills and qualifications needed to thrive as a bioinformatics software developer?

To thrive as a Bioinformatics Software Developer, you need strong programming skills (especially in Python, R, or Java), a solid foundation in computational biology, and typically a degree in computer science, bioinformatics, or a related field. Familiarity with bioinformatics tools (such as BLAST, Bioconductor, or Galaxy), experience with version control systems like Git, and understanding databases and cloud platforms are commonly required. Collaboration, problem-solving abilities, and strong communication skills help facilitate effective teamwork across interdisciplinary scientific teams. These competencies are vital for developing robust software solutions that address complex biological data challenges encountered in research and healthcare settings.

What are some common challenges faced by bioinformatics software developers in their daily work?

Bioinformatics Software Developers often work with large and complex biological datasets, which can present challenges in terms of data integration, processing efficiency, and scalability. Keeping up with rapidly evolving research methodologies and integrating new scientific findings into software solutions can also be demanding. Developers must collaborate closely with biologists, researchers, and other IT professionals to ensure that the tools they build meet scientific needs and are user-friendly. Strong problem-solving skills and adaptability help in overcoming technical and domain-specific obstacles, making this a dynamic and intellectually rewarding career choice.

What are popular job titles related to Bioinformatics Software Developer jobs in California?

For Bioinformatics Software Developer jobs in California, the most frequently searched job titles are:

What job categories do people searching Bioinformatics Software Developer jobs in California look for?

The top searched job categories for Bioinformatics Software Developer jobs in California are:

Bioinformatics Software Developer jobs near you
Infographic showing various Bioinformatics Software Developer job openings in California as of September 2026, with employment types broken down into 1% Internship, 1% As Needed, 83% Full Time, 12% Part Time, 1% Temporary, and 2% Contract. Highlights an 84% Physical, 3% Hybrid, and 13% Remote job distribution, with an average salary of $87,834 per year, or $42.2 per hour.

Bioinformatics Engineer

South San Francisco, CA • On-site

The Select Group
501 - 1,000 employees
Learn more about The Select Groupexternal

Full-time

Re-posted 5 days ago

Job description

BIOINFORMATICS ENGINEER | SAN FRANCISCO, CA
The Select Group is seeking a Bioinformatics Engineer to join one of our top biotechnology partners in the Fortune 100. This team works with next gen sequencing and diagnostic instruments that help detect lung cancer and reproductive diseases. This person will be working on the bioinformatics pipeline and will be testing existing and new features on the next gen sequencing applications/platforms. Note, working hours will be 9:00am-5:00pm PST.
BIOINFORMATICS ENGINEER REQUIREMENTS
  • Bachelors Degree and 5+ years of relevant work experience OR Masters Degree and 3+ years of relevant experience OR PhD and 2+ years of relevant experience
    • Degree should be in Bioinformatics, Chemistry, Biology, Biochemistry, Computational Science, or a similar scientific field
  • 3 years of coding experience and proficiency with at least 1 language (preference on Python)
  • Familiarity and experience with Linux command lines
  • Prior experience with next gen sequencing
  • Must have documentation experience (likely will not be listed on resume)
  • Soft skills: detail oriented, team player, flexible, able to work in fast paced environments

Bonus skills:
  • Oncology experience (huge plus)
  • FDA Compliance 21 CFR documentation experience
  • Test development experience with Java
  • Experience with Selenium
  • Familiarity with mapping algorithm development

BIOINFORMATICS ENGINEER RESPONSIBILITIES
  • Analyze the requirements for data analysis pipelines and visualizations to support various applications (Oncology, Reproseq, Immuno-oncology, CarrierSeq etc) and translate them to software specifications.
  • Help software development team to understand and design the complex Informatics and Data Visualization features. Work closely with developers to implement software features
  • Write and execute test protocols to validate the features and data analysis pipelines
  • Troubleshooting the data analysis pipeline and software issues.
  • Check the correctness of output Compare output data with other equivalent systems
  • Perform system performance profiling
  • Perform test automation with Python and Java
  • Prepare FDA submission documentation when needed
  • Collaborate with cross functional team

TSG is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
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