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Best Startup Jobs in Raleigh, NC (NOW HIRING)

Pinnaql

Validation Engineer

Greenville, NC

FAT, SAT, CSV, equipment integration, and startup. * Drive process design for new equipment and ... We believe that when you're empowered to do your best work, bold ideas thrive and real progress ...

Pinnaql

Validation Engineer

Holly Springs, NC · On-site

FAT, SAT, CSV, equipment integration, and startup. * Drive process design for new equipment and ... We believe that when you're empowered to do your best work, bold ideas thrive and real progress ...

MSS Solutions, LLC

Installer - TRK/INF

Zebulon, NC · On-site

A career at MSS is not just a job -- it's collaborating with the business's best talent. It ... Startup and verify performance * Recover, secure electrically and demo existing equipment needing ...

Siemens

Electrician

Knightdale, NC · On-site

$44K - $76K/yr

This position will be based in Raleigh/Knightdale, NC, a new greenfield startup plant. Overview ... Follow and support Siemens safety rules, policies, and best practices * Ensure compliance with ...

Siemens Mobility

Electrician

Raleigh, NC · On-site

$45 - $76/hr

The role is a key technical contributor in a manufacturing startup environment and supports skid ... Follow and support Siemens safety rules, policies, and best practices * Ensure compliance with ...

MSS Solutions LLC

Installer - TRK/INF

Zebulon, NC · On-site

A career at MSS is not just a job -- it's collaborating with the business's best talent. It ... Startup and verify performance * Recover, secure electrically and demo existing equipment needing ...

MSS Solutions LLC

Installer - TRK/INF

Zebulon, NC · On-site

A career at MSS is not just a job -- it's collaborating with the business's best talent. It ... Startup and verify performance * Recover, secure electrically and demo existing equipment needing ...

Vulcan Elements

Sr. Manufacturing Engineer

Durham, NC · On-site

$87K - $120K/yr

Hands-on Startup Support: Provide hands-on support during production startup, helping stabilize ... best-in-class magnet manufacturing. * EHS & Quality Compliance: Ensure compliance with safety ...

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Best Startup information

See Raleigh, NC salary details

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How much do best startup jobs pay per hour?

As of Sep 6, 2026, the average hourly pay for best startup in Raleigh, NC is $16.51, according to ZipRecruiter salary data. Most workers in this role earn between $15.87 and $17.07 per hour, depending on experience, location, and employer.

What is the difference between Best Startup vs Best Startup Developer?

AspectBest StartupBest Startup Developer
Required CredentialsVaries, often includes business or technical degreesTechnical degrees, coding certifications, programming skills
Work EnvironmentFast-paced, innovative startup settingTechnical teams within startup environment, collaborative
Employer & Industry UsageStartup companies across various sectorsTech-focused startups, software development firms
Search & Comparison IntentLooking for top startup companies or opportunitiesComparing roles for startup developers or coding positions

The comparison between Best Startup and Best Startup Developer highlights that while both are associated with startup environments, the former refers broadly to top startup companies, and the latter focuses specifically on developer roles within startups. Understanding these differences helps job seekers target the right opportunities based on their skills and career goals.

Best Startup jobs near you
Infographic showing various Best Startup job openings in Raleigh, NC as of August 2026, with employment types broken down into 84% Full Time, 11% Part Time, and 5% Contract. Highlights an 74% In-person, and 26% Remote job distribution, with an average salary of $34,346 per year, or $16.5 per hour.

Front Line Manufacturing Manager - Upstream Bulk Drug Substance - Days

Amgen

Holly Springs, NC

Full-time

Medical, Dental, Vision, Life, Retirement

Re-posted 10 days ago

Job description

Career CategoryManufacturingJob Description

Join Amgen's Mission of Serving Patients

At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.

Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Be part of Amgen's next generation drug substance manufacturing facility in North Carolina. We are starting up our first facility and breaking ground on our second facility. Both facilities feature the best in-class drug substance technologies and integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.

If you feel like you're part of something bigger, it's because you are. At Amgen, our shared mission-to serve patients-drives all that we do. It is key to our becoming one of the world's leading biotechnology companies. We are global collaborators who achieve together-researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It's time for a career you can be proud of. Join us.

Front Line Manufacturing Manager - Upstream Bulk Drug Substance - Days

What you will do

Let'sdo this.Let'schange the world.Amgen is seeking a Manager ManufacturingUpstreamto provide frontline leadership supporting the facility expansion program and facility startup. Thisessentialrole will lead a team responsible for manufacturingcell cultureoperationsincluding seed train, SUBs, Perfusion, RTF, Stainless Steel BRXs, Depth Filtration and Centrifugation,while partnering across functions to ensure successful operational readiness, technology transfer, and rampup of manufacturing operations within the new facility.

The Manager will play a critical role supporting the design, build, startup, and operational phases of the facility expansion. The position will initially focus on facility startup and operational readiness activities, transitioning to manufacturing leadership as the facility becomes operational.During this phase of thestartup, you will be expected toworkaMonday - Friday schedule from 8am - 5pm.

This role may require work outside standard business hours, including nonstandard shifts, as needed to support startup, commissioning and qualification (C&Q), and engineering execution.As the business moves from C&Q to manufacturing operations, this essential positionwillwork ona 12-hour 2-2-3 schedule from 5:45 am to6:15pmsupporting our critical 24/7 manufacturing operations.As Amgen relies upon the regular attendance of all staff members to meet legitimate business needs, the Manager must be able to work assigned 12-hourshift, including during inclement weather, some holidays and requested overtime in support of our operations.

Responsibilities

  • Frontline Leadership:Lead, develop, and coach a manufacturing team; set clear performance expectations; foster a strong culture of safety, quality, and accountability.

  • Facility Startup & Operational Readiness:Support design, build, commissioning, qualification (C&Q), staffing, training, and readiness milestones for a new manufacturing facility.

  • Manufacturing Operations: Ensure safe, cGMPcompliant execution; drive performance across safety, quality, schedule, and cost; resolve deviations and operational issues.

  • Technology Transfer & Process Implementation:Support transfer and implementation of manufacturing processes; ensure manufacturability, troubleshooting, and continuous improvement.

  • CrossFunctional Collaboration:Partner with Quality, Engineering, NPI, Supply Chain, Validation, and Site Leadership to enable successful startup and rampup.

  • Compliance & Inspection Readiness:Maintaininspection readiness and adherence to regulatory and Amgen quality standards.

  • Continuous Improvement:Identifyand drive efficiency, reliability, and scalability improvements as operations mature.

  • Shift Support:Work nonstandard hours asrequired, transitioning to a 12hour 223 dayshift supporting 24/7 operations.

Win

What we expect from you

We are all different, yet we all use our unique contributions to serve patients. Thebiotechnologyprofessional weseekis amanagerwith these qualifications.

Basic Qualifications

  • Doctoratedegree OR

  • Master's degreeand3years ofManufacturing or Operationsexperience OR

  • Bachelor's degree and5years ofManufacturing or Operationsexperience OR

  • Associate's degree and 10 years of ManufacturingorOperations experience OR

  • High school diploma / GED and 12 years of ManufacturingorOperations experience

  • AND Previous managerial experience directly managing people and/or experience leading teams, projects, programs or directing the allocation of resources

Preferred Qualifications

  • Bachelor's degree in Life Sciences or Engineering

  • Experience with facility startup, commissioning, or operational readiness

  • Biologics / drug substance manufacturing experience (Upstream)

  • cGMP manufacturing experience (5+ years preferred)

  • Experience with technology transfer and process implementation

  • Prior Area Lead / Specialist / Manager experience

  • Strong leadership, performance management, and conflictresolution skills

  • Solid understanding of regulatory requirements

  • Proficiencywith MES/EBR,DeltaV, Maximo, Veeva, LIMS, and electronic quality systems

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates' professional and personal growth and well-being.

The annual base salary range for this opportunity in the U.S. is provided below.

In addition to the base salary, Amgen offers a Total Rewards Plancomprisinghealth and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

  • Stock-based long-term incentives

  • Award-winning time-off plans and bi-annual company-wide shutdowns

  • Flexible work models, including remote work arrangements, where possible

Apply nowfor a career that defies imagination

Objects in your future are closer than they appear. Join us.

careers.amgen.com

#AmgenNorthCarolina

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Salary Range

106,148.00USD -143,612.00USD

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