ZipRecruiter

Log In

1

Associate Downstream Process Development Scientist Jobs in Pittsburgh, PA

Form Energy

Senior Cathode Process Development Engineer

Weirton, WV · On-site

$101K - $131K/yr

Provide technical guidance to a team of technicians and associates * Champion safety by partnering ... Bachelors Engineering, material science, or equivalent STEM background Where you'll work: This role ...

Posted today

ATI

Process Engineer

Vandergrift, PA · On-site

In this position you will be responsible for process development and improvement, and quality cost ... Bachelor's degree in Material Science, Metallurgical Engineering, Chemical Engineering, or related ...

ATI

Process Engineer

Vandergrift, PA · On-site

In this position you will be responsible for process development and improvement, and quality cost ... Bachelor's degree in Material Science, Metallurgical Engineering, Chemical Engineering, or related ...

Next Gen Alloys

Process Engineer

Vandergrift, PA · On-site

In this position you will be responsible for process development and improvement, and quality cost ... Bachelor's degree in Material Science, Metallurgical Engineering, Chemical Engineering, or related ...

ElevateBio

Engineer I, MSAT

Pittsburgh, PA · On-site

The Role As a Process Engineer for Manufacturing Science and Technology (MSAT), you will provide process science support for GMP manufacturing, technology transfers, development studies ...

Form Energy

Process Engineer II, Welding

Weirton, WV · On-site

... Materials Science, Welding Engineering, or equivalent * Demonstrated mastery in owning welding ... Advanced proficiency using statistical methods for making process development decisions (using JMP ...

Form Energy

Process Engineer II, Welding

Weirton, WV · On-site

... Materials Science, Welding Engineering, or equivalent * Demonstrated mastery in owning welding ... Advanced proficiency using statistical methods for making process development decisions (using JMP ...

PPG

Product Development Operation Lead

Monroeville, PA · On-site

$113K - $141K/yr

... Science, Chemical Technology, or a related technical discipline preferred. * Minimum 2 to 4 years of experience in chemical manufacturing, process development, pilot plant operations, specialty ...

next page

Showing results 1-20

All JobsAssociate Downstream Process Development Scientist JobsAssociate Downstream Process Development Scientist Jobs in Pittsburgh, PA

Associate Downstream Process Development Scientist information

See Pittsburgh, PA salary details

$18

$32

$48

How much do associate downstream process development scientist jobs pay per hour?

As of Sep 11, 2026, the average hourly pay for associate downstream process development scientist in Pittsburgh, PA is $32.70, according to ZipRecruiter salary data. Most workers in this role earn between $26.83 and $40.14 per hour, depending on experience, location, and employer.

What is an associate downstream process development scientist?

An Associate Downstream Process Development Scientist is a professional who works in the biotechnology or pharmaceutical industry, focusing on developing and optimizing processes that purify biological products, such as proteins or antibodies, after they have been produced by cells. Their work is crucial for ensuring the final product meets quality and safety standards before it is used in research or clinical applications. They typically perform laboratory experiments, analyze data, and collaborate with other scientists and engineers to improve yield and efficiency. This role is often entry-level or early-career, providing hands-on experience in process development and technical troubleshooting.

What are some typical challenges faced by an associate downstream process development scientist, and how can they be addressed?

Associate Downstream Process Development Scientists often encounter challenges such as optimizing purification processes, troubleshooting equipment performance, and ensuring batch-to-batch consistency. These challenges can be addressed by maintaining meticulous documentation, collaborating closely with upstream and analytical teams, and staying current with best practices in chromatography and filtration. Proactively seeking feedback from experienced colleagues and participating in cross-functional meetings can also help in identifying solutions and improving process efficiency.

What are the key skills and qualifications needed to thrive as an associate downstream process development scientist, and why are they important?

To excel as an Associate Downstream Process Development Scientist, you need a solid understanding of biochemistry, chemical engineering, and downstream purification techniques, often supported by a bachelor's or master's degree in a life science or engineering discipline. Familiarity with chromatographic systems (such as AKTA), filtration equipment, and analytical tools, as well as knowledge of GMP/GLP regulations, is typically required. Strong problem-solving, attention to detail, and effective teamwork and communication skills help you navigate complex experiments and collaborate with cross-functional teams. These skills ensure efficient process optimization, compliance with regulatory standards, and successful development of biopharmaceutical products.

What is the difference between Associate Downstream Process Development Scientist vs Associate Upstream Process Development Scientist?

AspectAssociate Downstream Process Development ScientistAssociate Upstream Process Development Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Required SkillsProtein purification, chromatography, filtrationCell culture, bioreactor operation, media preparation
Work EnvironmentLaboratories, manufacturing facilitiesLaboratories, bioreactor labs
Common CertificationsBiotech or bioprocessing certificationsBiotech or bioprocessing certifications

Both roles are essential in biopharmaceutical development, focusing on different stages of the production process. The Associate Downstream Process Development Scientist specializes in purification techniques, while the Associate Upstream Process Development Scientist concentrates on cell growth and fermentation. Understanding these distinctions helps candidates target their skills and career paths effectively.

What cities near Pittsburgh, PA are hiring for Associate Downstream Process Development Scientist jobs?

Cities near Pittsburgh, PA with the most Associate Downstream Process Development Scientist job openings:

Associate Downstream Process Development Scientist jobs near you
Infographic showing various Associate Downstream Process Development Scientist job openings in Pittsburgh, PA as of September 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $68,016 per year, or $32.7 per hour.

Research Associate, Upstream Process Development

Pittsburgh, PA • On-site

Krystal Biotech
Biotechnology Research and Development • 51 - 200 employees
Learn more about Krystal Biotechexternal

Full-time

Posted 7 days ago

Job description

About Krystal Bio: At Krystal Biotech, we bring together the brightest and most eager minds to relentlessly pursue the discovery, development, manufacturing, and commercialization of genetic medicines to treat diseases with high unmet medical needs.
Founded in 2016, Krystal is distinguished in three powerful ways: science and technology using our patented gene therapy platform, innovative manufacturing supported by our commercial scale facilities, and a unique commercialization model that focuses on the patient’s end-to-end experience.
Krystal received U.S. FDA approval for the first and only redosable gene therapy treatment, VYJUVEK®, for the treatment of Dystrophic Epidermolysis Bullosa (DEB). Krystal continues to leverage our proprietary platform to rapidly advance a robust pipeline of investigational genetic medicines in respiratory, oncology, dermatology, and ophthalmology.
Krystal is headquartered in Pittsburgh, PA, which is home to our two state-of-the-art CGMP manufacturing facilities with teams around the world and satellite offices in Switzerland, Germany, and Japan. We are a company built and run by people who care, are fearless in the face of a challenge, love the work they do, and practice the highest level of scientific integrity. As we grow, we are seeking team members that embody these values.
Position Summary:
Krystal Biotech, Inc. is seeking a highly motivated and innovative Research Associate to support multidisciplinary efforts in Upstream Process Development.
The Research Associate will support process development initiatives by conducting experiments related to the characterization, optimization, and scale-up of viral vector production. They will support the tech transfer of developed processes to the Manufacturing team.
Primary Responsibilities:
  • Set up and operate bench scale bioreactors under the guidance of senior staff
  • Perform mammalian cell culture using aseptic techniques
  • Prepare buffers and media, maintain equipment, and order supplies to ensure the lab runs smoothly
  • Provide technical support in the lab through equipment maintenance and troubleshooting
  • Participate in study design and process development brainstorming sessions
  • Design scientifically sound experiments and record data accurately in electronic lab notebooks
  • Adhere to safety guidelines and maintain a clean and orderly lab environment
  • Analyze experimental data and effectively communicate findings with manager and rest of process development team
  • Interact with cross-functional teams (manufacturing, MSAT, etc.) to identify and solve problems encountered during process scale-up
Requirements and Preferred Qualifications:
  • Bachelor’s Degree in Biomedical Engineering, Chemical Engineering, Bioengineering or a related scientific discipline.
  • Some understanding in one or more of the following areas: aseptic technique, mammalian cell culture, bioreactor technology, cell biology, and/or virology
  • Familiarity with bioreactor operation and upstream processing is a plus
  • Familiarity with lab automation or basic coding is a plus
  • High capability of multitasking in a fast-paced team-oriented environment
  • Excellent oral and written communication skills

Krystal Biotech, Inc. is an Equal Employment Opportunity and Affirmative Action Employers. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender perception or identity, national origin, age, marital status, protected veteran status, or disability status. Headhunters and recruitment agencies may not submit resumes/CVs through this Web site or directly to managers. Krystal Biotech, Inc. does not accept unsolicited headhunter and agency resumes. Krystal Biotech, Inc.  will not pay fees to any third-party agency or company that does not have a signed agreement with Krystal Biotech, Inc.

Powered by JazzHR

5hYuu1kGrj