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Associate Downstream Process Development Scientist Jobs in Texas

Lonza

R&D Scientist

Houston, TX · On-site

R&D Scientist Location: This is an on-site position located in Pearland, TX The purpose of this ... process development and commercial development. * Capable of achieving deliverables on-time and ...

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Associate Downstream Process Development Scientist information

What are the key skills and qualifications needed to thrive as an Associate Downstream Process Development Scientist, and why are they important?

To excel as an Associate Downstream Process Development Scientist, you need a solid understanding of biochemistry, chemical engineering, and downstream purification techniques, often supported by a bachelor's or master's degree in a life science or engineering discipline. Familiarity with chromatographic systems (such as AKTA), filtration equipment, and analytical tools, as well as knowledge of GMP/GLP regulations, is typically required. Strong problem-solving, attention to detail, and effective teamwork and communication skills help you navigate complex experiments and collaborate with cross-functional teams. These skills ensure efficient process optimization, compliance with regulatory standards, and successful development of biopharmaceutical products.

What are some typical challenges faced by an Associate Downstream Process Development Scientist, and how can they be addressed?

Associate Downstream Process Development Scientists often encounter challenges such as optimizing purification processes, troubleshooting equipment performance, and ensuring batch-to-batch consistency. These challenges can be addressed by maintaining meticulous documentation, collaborating closely with upstream and analytical teams, and staying current with best practices in chromatography and filtration. Proactively seeking feedback from experienced colleagues and participating in cross-functional meetings can also help in identifying solutions and improving process efficiency.

What is an Associate Downstream Process Development Scientist?

An Associate Downstream Process Development Scientist is a professional who works in the biotechnology or pharmaceutical industry, focusing on developing and optimizing processes that purify biological products, such as proteins or antibodies, after they have been produced by cells. Their work is crucial for ensuring the final product meets quality and safety standards before it is used in research or clinical applications. They typically perform laboratory experiments, analyze data, and collaborate with other scientists and engineers to improve yield and efficiency. This role is often entry-level or early-career, providing hands-on experience in process development and technical troubleshooting.

What is the difference between Associate Downstream Process Development Scientist vs Associate Upstream Process Development Scientist?

AspectAssociate Downstream Process Development ScientistAssociate Upstream Process Development Scientist
Primary FocusPurification and recovery of bioproductsCell culture and fermentation processes
Required SkillsProtein purification, chromatography, filtrationCell culture, bioreactor operation, media preparation
Work EnvironmentLaboratories, manufacturing facilitiesLaboratories, bioreactor labs
Common CertificationsBiotech or bioprocessing certificationsBiotech or bioprocessing certifications

Both roles are essential in biopharmaceutical development, focusing on different stages of the production process. The Associate Downstream Process Development Scientist specializes in purification techniques, while the Associate Upstream Process Development Scientist concentrates on cell growth and fermentation. Understanding these distinctions helps candidates target their skills and career paths effectively.

What are the most commonly searched types of Downstream Process Development Scientist jobs in Texas? The most popular types of Downstream Process Development Scientist jobs in Texas are:
What cities in Texas are hiring for Associate Downstream Process Development Scientist jobs? Cities in Texas with the most Associate Downstream Process Development Scientist job openings:
Associate Downstream Process Development Scientist jobs near you

R&D Scientist

Lonza

Houston, TX • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 4 days ago

Lonza rating

8.1

Company rating: 8.1 out of 10

Based on 39 frontline employees who took The Breakroom Quiz

33rd of 71 rated pharmaceutical

Job description

R&D Scientist
Location: This is an on-site position located in Pearland, TX
The purpose of this role is to drive innovation in the development of novel scalable viral vector production platforms for use in in vivo and ex vivo gene therapy applications. The successful candidate will support in identifying, developing and implementing viral vector production technologies, using resources internal and external to Lonza, in order to support in creating scalable robust solutions to viral production bottlenecks. This hands-on bioprocess scientist will design and execute experiments, develop metrics for evaluating results and technologies and procure equipment. The incumbent will be responsible for acquiring, analyzing, and communicating experimental data in cross-functional fashion.
What you will get:
A competitive compensation. In addition, below you will find a comprehensive summary of the benefits package we offer:
  • Performance-related bonus.
  • Medical, dental and vision insurance.
  • 401(k) matching plan.
  • Life insurance, as well as short-term and long-term disability insurance.
  • Employee assistance programs.
  • Paid time off (PTO).

Compensation for this role will be determined by the candidate's qualifications, skills, experience, and relevant knowledge.
What you will do:
  • Plan, design and execute the experiments, including but not limited to cell culture, transfection, viral transduction/infection and analytical work associated with the project.
  • Collect and analyze the data, interpret the results and evaluate next steps in experimental design.
  • Effectively communicate the data and project progress regularly within R&D and across the key stakeholders/departments such as process development and commercial development.
  • Capable of achieving deliverables on-time and high-quality.
  • Maintains accurate and up to date records, including appropriate lab notebook recordings.
  • Actively work on improving viral vector designs for the platforms, to attract and anchor new clients together with cross-functional teams.
  • Actively propose and test new ideas, capture and protect intellectual property with patent applications in order to create long-term competitive technology advantages for Lonza CGT business.
  • Attend meetings and conferences to present R&D work and keep up with the latest technology in cell and gene therapy regarding the viral vector manufacturing and analytics.

What we are looking for:
  • Ph.D. degree in molecular virology/biology with 0-4 years' experience in industry, or relevant virus research experience in academia evidenced by peer-reviewed publications.
  • Skilled in plasmid vector design, cell line engineering, viral production, transfection, Western blot, qPCR/ddPCR, flow cytometry and cell-based assays.
  • Excellent communication skills in oral and written English.
  • The ability to thrive in a multi-disciplinary, collaborative environment is essential.
  • Independence and strong work ethic are a must.

About Lonza:
At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone's ideas, big or small, have the potential to improve millions of lives, and that's the kind of work we want you to be part of.
Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law. If you're ready to help turn our customers' breakthrough ideas into viable therapies, we look forward to welcoming you on board.
Ready to shape the future of life sciences? Apply now.

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