ZipRecruiter

Log In

1

Associate Director Clinical Scientist Jobs (NOW HIRING)

eGenesis

Associate Director, Clinical Science

Cambridge, MA · On-site

$175K - $226K/yr

POSITION SUMMARY The Associate Director, Clinical Science is responsible for the planning, execution and operational oversight of clinical development programs supporting the advancement of eGenesis ...

eGenesis

Associate Director, Clinical Science

Cambridge, MA · On-site

$175K - $226K/yr

POSITION SUMMARY The Associate Director, Clinical Science is responsible for the planning, execution and operational oversight of clinical development programs supporting the advancement of eGenesis ...

eGenesis

Associate Director, Clinical Science

Cambridge, MA · On-site

$175K - $226K/yr

POSITION SUMMARY The Associate Director, Clinical Science is responsible for the planning, execution and operational oversight of clinical development programs supporting the advancement of eGenesis ...

previous page

Showing results 41-60

All JobsScience JobsResearch JobsResearch Scientist JobsAssociate Director Clinical Scientist Jobs

Associate Director Clinical Scientist information

See salary details

$28

$54

$81

How much do associate director clinical scientist jobs pay per hour?

As of Sep 9, 2026, the average hourly pay for associate director clinical scientist in the United States is $54.75, according to ZipRecruiter salary data. Most workers in this role earn between $40.14 and $68.27 per hour, depending on experience, location, and employer.

What does an associate director clinical scientist do?

An Associate Director Clinical Scientist is responsible for leading and managing clinical research activities within a pharmaceutical or biotechnology company. They oversee the design, implementation, and analysis of clinical trials, ensuring scientific integrity and regulatory compliance. This role also involves collaborating with cross-functional teams, interpreting clinical data, and contributing to the development of clinical strategies for drug development. Associate Directors often mentor junior staff and play a key role in communicating results to stakeholders.

What are the key skills and qualifications needed to thrive as an associate director clinical scientist?

To thrive as an Associate Director Clinical Scientist, you need an advanced degree in life sciences or medicine, extensive clinical research experience, and a deep understanding of drug development processes. Familiarity with clinical trial management systems, regulatory submission tools, and relevant certifications such as GCP are typically required. Strong leadership, strategic thinking, and excellent communication skills help drive cross-functional teams and effectively present scientific data. These competencies are crucial for ensuring robust clinical trial design, regulatory compliance, and impactful scientific contributions to pipeline advancement.

What are some common challenges faced by an associate director clinical scientist when managing cross-functional clinical project teams?

An Associate Director Clinical Scientist often encounters challenges in aligning diverse teams, such as clinical operations, data management, and regulatory affairs, toward common project goals. Balancing scientific rigor with operational timelines requires strong communication and negotiation skills, especially when addressing conflicting priorities or resource constraints. Additionally, ensuring compliance with evolving regulatory standards and maintaining data integrity across global studies can add complexity. Success in this role often depends on proactive problem-solving and fostering a collaborative team environment.

What is the difference between Associate Director Clinical Scientist vs Clinical Scientist?

AspectAssociate Director Clinical ScientistClinical Scientist
Required CredentialsTypically requires a PhD or MD, with several years of experience in clinical researchUsually requires a Bachelor's, Master's, or PhD in a related field
Work EnvironmentLeads cross-functional teams, involved in strategic planning and oversightConducts clinical trials, data analysis, and supports study operations
Employer & Industry UsageCommonly found in pharmaceutical and biotech companies, often in senior rolesFound across industry settings, including CROs and pharma, in operational roles

The Associate Director Clinical Scientist typically holds a more senior, strategic role with leadership responsibilities, while the Clinical Scientist focuses on executing clinical research activities. Both roles require strong scientific expertise, but the Associate Director often oversees projects and teams, guiding overall clinical development efforts.

What cities are hiring for Associate Director Clinical Scientist jobs?

Cities with the most Associate Director Clinical Scientist job openings:

What are popular job titles related to Associate Director Clinical Scientist jobs?

For Associate Director Clinical Scientist jobs, the most frequently searched job titles are:

Infographic showing various Associate Director Clinical Scientist job openings in the United States as of August 2026, with employment types broken down into 3% As Needed, 74% Full Time, 15% Part Time, and 8% Contract. Highlights an 85% Physical, 1% Hybrid, and 14% Remote job distribution, with an average salary of $113,877 per year, or $54.7 per hour.

Director, Clinical Scientist - Neuroimmunology

Cambridge, MA • On-site

AstraZeneca
Pharmaceutical Product Wholesalers • 10K+ employees
Learn more about AstraZenecaexternal

Full-time

Medical, Dental, Vision, Retirement, PTO

This job post has expired 1 day ago. Applications are no longer accepted.

AstraZeneca rating

8.4

Company rating: 8.4 out of 10

Based on 45 frontline employees who took The Breakroom Quiz

23rd of 86 rated pharmaceutical

Job description

Are you an experienced clinical scientist who wants to help bring transformative cell and immunotherapies to patients with serious immune-mediated neurological disease? Do you combine deep hands-on study execution, from medical and data review to endpoint integrity and document authorship, with the judgment to run the clinical-science engine of a trial with minimal escalation? Do you thrive where strategy meets day-to-day ownership, and enjoy mentoring more junior scientists? If so, we invite you to join us. We are seeking a Director, Clinical Scientist, Neuroimmunology to drive study-level clinical science across our neuroimmunology portfolio, starting in multiple sclerosis and extending to additional immune-mediated neurologic indications.
The Director, Clinical Scientist leads the day-to-day clinical-science engine of one or more studies, working synergistically with the Study Physician as the expert on the medical-scientific and operational-science aspects of our compounds and their development. You will report to the Global Clinical Head, Neuroimmunology, or their designee, and partnering closely with the Study Physician and the Global Clinical Program Lead (GCPL), you will translate the program's clinical development plan into inspection-ready, decision-enabling studies. You will own document cycles, continuous medical and data review, endpoint integrity, and the site and CRO clinical-science interface, so that routine clinical-science work is handled at the study level. You will operate in compliance with GCP, AZ quality systems, and relevant regulatory guidelines, and will help develop and mentor junior clinical scientists. The GCPL leads the program's clinical development strategy and holds program-level accountability. Medical judgement, benefit-risk, and final medical sign-off sit with the Study Physician; program strategy and cross-study trade-offs are set with the GCPL.
Typical Accountabilities
Document ownership and operational translation
  • Act as lead author and reviewer for study-level documents in alignment with the clinical development plan, including protocols and amendments, IB updates, ICFs, clinical and scientific training materials, medical monitoring plans, and charters such as MRI central read and relapse adjudication. Manage version control and cross-document consistency.
  • Translate protocol intent into operational deliverables such as CRFs and eCRF completion guidelines, lab and pharmacy manuals, and rater guidance. Own the protocol clarification log and ensure site workflows support endpoint quality and data timeliness.
  • Ensure clinical study protocols and associated documents align with the clinical development plan and connect trial data to the Target Product Profile.

Ongoing medical and data review and safety-surveillance partnership
  • Perform routine, independent review of patient profiles, listings, coded terms, and narratives. Run trend checks across safety, efficacy, and protocol compliance, and maintain issue, action, and decision logs, driving timely closure.
  • Contribute to the interpretation of emerging clinical data and identification of clinically meaningful findings, trends, and questions for further evaluation by the study team.
  • Own the day-to-day execution of study-level medical oversight as defined in the Study-Level Medical Oversight Plan (SLMOP), ensuring participant-level and aggregate reviews occur at the specified frequencies, with outcomes documented and filed to the TMF per SOP and SLMOP timelines.
  • Partner with Pharmacovigilance on AE and SAE triage, reconciliation, and timely narrative drafting. Conduct AESI reviews and trending (these include CRS, neurotoxicity/ICANS, infections, IEC-HS, IEC-associated colitis, and new malignancies), prepare SRC, IDMC, and DMC safety packets, and flag emerging signals promptly with proposed next steps, bringing medical-judgement items to the Study Physician.
  • Perform real-time participant-level eligibility reviews during screening, and drive query generation, coding reconciliation, and edit-check refinement with Data Management and Biostatistics.

Endpoint integrity (MS-specific)
  • Own the operational integrity of MS assessments, including MRI central-read charter adherence, EDSS scoring accuracy and FSS concordance, and relapse-adjudication package completeness. Monitor inter-rater reliability and vendor performance, and drive rater and vendor CAPAs where needed.

Data readiness, SAP/TLF alignment, and decision enablement
  • Lead the query and data-cleaning strategy to hit LPLV, interim, and database-lock milestones with inspection-ready documentation.
  • Ensure traceability from protocol to SAP and TLF shells, review analysis populations, estimands, and endpoints, and validate mock outputs for decision quality.
  • Build clear, integrated readouts across safety, efficacy, PK/PD, biomarkers, and operations, with options and recommendations for governance, and maintain decision and assumption logs.

External interface, regulatory support, and disclosures
  • Serve as first-line clinical and scientific responder for routine questions from sites and CROs, providing consistent, timely clarifications, support site initiation visits and investigator meetings. Lead root-cause analysis and CAPAs with Clinical Operations and vendors.
  • Draft and review clinical sections of regulatory documents and responses, including HA interactions, briefing books, IND and annual reports, PIPs, and safety updates, ensuring SLMOP-driven surveillance outputs are reflected accurately and aligned with GCP, ICH, FDA, and EMA expectations.
  • Lead development, review, and quality of abstracts, posters, manuscripts, and scientific presentations, ensuring data coherence across disclosures.

Mentorship and continuous learning
  • Provide study-specific onboarding and support for Study Physicians and coach junior Clinical Scientists on study background, systems, oversight processes, and effective communication and expectations.
  • Track key developments in the MS, neuroimmunology, and cell-therapy literature and competitive landscape, and propose pragmatic protocol or analysis optimizations that improve probability of success without destabilizing operations.

Essential Qualifications and Skills
  • Advanced scientific or clinical degree (PhD, PharmD, MD, or equivalent) in a life-sciences or related field.
  • At least 6 years' clinical-development experience, with strong hands-on study execution and medical and data review. Neurology or multiple sclerosis experience preferred.
  • Proven experience designing and delivering clinical trials, including protocol and ICF development, medical monitoring and safety data review, IB and DSUR contributions, clinical data review and interpretation, and CSR authorship.
  • Deep working knowledge of ICH-GCP and global regulatory expectations across Phase 1 and 2, with Phase 3 a plus, and experience contributing clinical-science content to regulatory interactions and submissions such as IND/CTA.
  • Proficiency with clinical databases, listings review, and coding, and effective collaboration with Biostatistics, Data Management, and Pharmacovigilance.
  • Command of clinical-trial methodology and statistical concepts sufficient to support data-driven decision-making.
  • Demonstrated cross-functional collaboration, the ability to influence internal and external stakeholders, learning agility, and solution-focused problem-solving.
  • Attention to detail, an ownership mindset, and a track record of delivering results.

Desirable Skills
  • Direct clinical-development experience in CAR-T or other engineered cell therapies, and/or T-cell engagers, across autoimmune or inflammatory indications, including operational constraints such as chain-of-identity/control and vein-to-vein logistics, and CMC-clinical interfaces.
  • Understanding of end-to-end cell-therapy development across research, clinical operations, clinical pharmacology, translational medicine, biostatistics, regulatory, safety, CMC, and commercial.
  • Experience mentoring or providing work direction to junior scientists.
  • External credibility with investigators, academic partners, consortia, and CROs.
  • Data-analysis and programming familiarity (for example R, SAS, Python) and clinical-review tools (for example Medidata Rave, J-Review).
  • Ability to travel nationally and internationally.

The annual base pay for this position ranges from $203K to $305K. Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
About AstraZeneca
AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that discovers, develops and commercializes prescription medicines for some of the world's most serious diseases. Within Immunology R&D, our Neuroimmunology team is building a world-class capability to accelerate the delivery of transformative cell therapies and immunotherapies for patients with immune-mediated neurological disease. AZ is a place built on courage, curiosity and collaboration, and we make bold decisions driven by patient outcomes.
Date Posted
28-Aug-2026
Closing Date
07-Sep-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

What AstraZeneca employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

AstraZeneca logo

About AstraZeneca

Sourced by ZipRecruiter

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. A place built on courage, curiosity and collaboration - we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take smart risks that write the next chapter for our pipeline and Oncology team. Make a meaningful impact that brings real benefits to society. By applying your knowledge of data, you will help to redefine our industry and ultimately save lives. Work with experts who share a common goal: to accelerate the potential of medicines and the science of tomorrow.

Industry

Pharmaceutical product wholesalers and pharmaceutical and medicine manufacturing

Company size

10,000+ Employees

Headquarters location

Cambridge, Cambridgeshire, GB

View All AstraZeneca Jobs

Apply