Generate, manage, evaluate, and maintain critical data in a highly organized manner, including the ... Extensive experience in immune cell-based analytics and assay development including but not limited ...
Generate, manage, evaluate, and maintain critical data in a highly organized manner, including the ... Extensive experience in immune cell-based analytics and assay development including but not limited ...
Provide leadership for target validation, mechanism-of-action studies, assay development, candidate ... Big Data Management, Data Reporting, Data Savvy, Drug Discovery Development, Molecular Diagnostics ...
Provide leadership for target validation, mechanism-of-action studies, assay development, candidate ... Big Data Management, Data Reporting, Data Savvy, Drug Discovery Development, Molecular Diagnostics ...
Provide leadership for target validation, mechanism-of-action studies, assay development, candidate ... Big Data Management, Data Reporting, Data Savvy, Drug Discovery Development, Molecular Diagnostics ...
Provide leadership for target validation, mechanism-of-action studies, assay development, candidate ... Big Data Management, Data Reporting, Data Savvy, Drug Discovery Development, Molecular Diagnostics ...
... assay development of new clinical assays which may include the optimization, qualification ... remote management, but also work collaboratively with a broader team and across functional ...
... assay development of new clinical assays which may include the optimization, qualification ... remote management, but also work collaboratively with a broader team and across functional ...
... assay development for phase 1 clinical studies and sample processing and analysis for larger phase ... managing large sample libraries and data sets. The candidate must maintain a record of studies in ...
... assay development for phase 1 clinical studies and sample processing and analysis for larger phase ... managing large sample libraries and data sets. The candidate must maintain a record of studies in ...
Lead assay selection, qualification/validation strategy and oversight (internal and external CROs ... Highly developed problem-solving, critical thinking, and risk management skills with exceptional ...
Lead assay selection, qualification/validation strategy and oversight (internal and external CROs ... Highly developed problem-solving, critical thinking, and risk management skills with exceptional ...
Sr. Scientist
Philadelphia, PA · On-site
$92K - $126K/yr
Generate, manage, evaluate, and maintain critical data in a highly organized manner, including the ... Extensive experience in immune cell-based analytics and assay development including but not limited ...
Sr. Scientist
Philadelphia, PA · On-site
$92K - $126K/yr
Generate, manage, evaluate, and maintain critical data in a highly organized manner, including the ... Extensive experience in immune cell-based analytics and assay development including but not limited ...
Scientist
Philadelphia, PA · On-site
Generate, manage, evaluate, and maintain critical data in a highly organized manner, including the ... Extensive experience in immune cell-based analytics and assay development including but not limited ...
Scientist
Philadelphia, PA · On-site
Generate, manage, evaluate, and maintain critical data in a highly organized manner, including the ... Extensive experience in immune cell-based analytics and assay development including but not limited ...
... assay development, commercial value, etc. Executing Pharmacogenomics and biomarker studies ... manage vendors in experimental set-up and implementation in clinical trials Collaboratively ...
... assay development, commercial value, etc. Executing Pharmacogenomics and biomarker studies ... manage vendors in experimental set-up and implementation in clinical trials Collaboratively ...
Research Associate II - Immunology
Philadelphia, PA · On-site
$30/hr
Reporting to the Senior Director of Immunology and/or Lab Manager, this position is a full-time on ... Contribute to assay development of new clinical assays which may include the optimization ...
Quick apply
Research Associate II - Immunology
Philadelphia, PA · On-site
$30/hr
Reporting to the Senior Director of Immunology and/or Lab Manager, this position is a full-time on ... Contribute to assay development of new clinical assays which may include the optimization ...
Senior Associate Scientist
Spring House, PA · On-site
$85K - $95K/yr
Coordinate routine maintenance, deep cleaning, vendor servicing, and replacement part management. Assay Development & Biologics Support * Develop and optimize biological and cell-based assays ...
Senior Associate Scientist
Spring House, PA · On-site
$85K - $95K/yr
Coordinate routine maintenance, deep cleaning, vendor servicing, and replacement part management. Assay Development & Biologics Support * Develop and optimize biological and cell-based assays ...
Senior Associate Scientist
Spring House, PA · On-site
$85K - $95K/yr
Coordinate routine maintenance, deep cleaning, vendor servicing, and replacement part management. Assay Development & Biologics Support * Develop and optimize biological and cell-based assays ...
Senior Associate Scientist
Spring House, PA · On-site
$85K - $95K/yr
Coordinate routine maintenance, deep cleaning, vendor servicing, and replacement part management. Assay Development & Biologics Support * Develop and optimize biological and cell-based assays ...
Senior Associate Scientist
Spring House, PA · On-site
$85K - $95K/yr
Coordinate routine maintenance, deep cleaning, vendor servicing, and replacement part management. Assay Development & Biologics Support * Develop and optimize biological and cell-based assays ...
Senior Associate Scientist
Spring House, PA · On-site
$85K - $95K/yr
Coordinate routine maintenance, deep cleaning, vendor servicing, and replacement part management. Assay Development & Biologics Support * Develop and optimize biological and cell-based assays ...
Postdoctoral Scholar
University Park, PA · On-site
... assay development, and vaccine development. Responsibilities for this position include developing ... Ability to manage multiple projects simultaneously * Strong problem-solving skills * Ability to ...
Postdoctoral Scholar
University Park, PA · On-site
... assay development, and vaccine development. Responsibilities for this position include developing ... Ability to manage multiple projects simultaneously * Strong problem-solving skills * Ability to ...
LIMS Consultant
Philadelphia, PA · On-site +1
Configure LIMS modules to support workflows, including assay development, plate results, sample management, stability, and analytical testing processes * Design, configure, and validate assay ...
LIMS Consultant
Philadelphia, PA · On-site +1
Configure LIMS modules to support workflows, including assay development, plate results, sample management, stability, and analytical testing processes * Design, configure, and validate assay ...
... assay development, and vaccine development. Responsibilities for this position include developing ... Ability to manage multiple projects simultaneously * Strong problem-solving skills * Ability to ...
... assay development, and vaccine development. Responsibilities for this position include developing ... Ability to manage multiple projects simultaneously * Strong problem-solving skills * Ability to ...
The Sr. R&D Manager - Upstream will lead upstream process development including Cloning, Expression ... assay materials, we partner with the brightest minds in biotech and pharma to tackle the world ...
The Sr. R&D Manager - Upstream will lead upstream process development including Cloning, Expression ... assay materials, we partner with the brightest minds in biotech and pharma to tackle the world ...
The Sr. R&D Manager - Upstream will lead upstream process development including Cloning, Expression ... assay materials, we partner with the brightest minds in biotech and pharma to tackle the world ...
The Sr. R&D Manager - Upstream will lead upstream process development including Cloning, Expression ... assay materials, we partner with the brightest minds in biotech and pharma to tackle the world ...
The Sr. R&D Manager - Upstream will lead upstream process development including Cloning, Expression ... assay materials, we partner with the brightest minds in biotech and pharma to tackle the world ...
The Sr. R&D Manager - Upstream will lead upstream process development including Cloning, Expression ... assay materials, we partner with the brightest minds in biotech and pharma to tackle the world ...
The Sr. R&D Manager - Upstream will lead upstream process development including Cloning, Expression ... assay materials, we partner with the brightest minds in biotech and pharma to tackle the world ...
The Sr. R&D Manager - Upstream will lead upstream process development including Cloning, Expression ... assay materials, we partner with the brightest minds in biotech and pharma to tackle the world ...
Assay Development Manager information
What are some common challenges faced by an assay development manager during the early stages of a new project?
One of the main challenges Assay Development Managers encounter in the early phases of a project is balancing the need for high sensitivity and specificity with practicality and scalability. They often need to troubleshoot unexpected assay variability, optimize protocols, and ensure the reproducibility of results under tight deadlines. Additionally, coordinating input from cross-functional teams—such as R&D scientists, quality assurance, and regulatory affairs—can present logistical hurdles. Effective communication and project management skills are essential to navigate these complexities and drive the project forward.
What is an assay development manager?
An Assay Development Manager is a scientific professional responsible for leading the design, development, validation, and optimization of laboratory assays, which are tests used to measure the presence or amount of a substance in biological samples. They manage teams of scientists and collaborate closely with research, quality, and regulatory departments to ensure assays meet scientific and regulatory requirements. Their work is vital in fields such as biotechnology, pharmaceuticals, and diagnostics, supporting drug discovery, disease diagnosis, and product development.
What is the difference between Assay Development Manager vs Laboratory Supervisor?
| Aspect | Assay Development Manager | Laboratory Supervisor |
|---|---|---|
| Credentials | Bachelor's/Master's in Life Sciences, relevant certifications | Bachelor's in Life Sciences or related field, relevant certifications |
| Work Environment | Research labs, biotech or pharma companies | Laboratories, clinical or research settings |
| Employer & Industry | Biotech, pharmaceutical, diagnostics | Research institutions, hospitals, biotech |
| Primary Focus | Designing and optimizing assays, project management | Overseeing daily lab operations, staff supervision |
The Assay Development Manager focuses on designing, developing, and optimizing assays, often managing projects and teams. In contrast, the Laboratory Supervisor oversees daily lab operations and staff, ensuring smooth workflow. Both roles require relevant scientific credentials and work in similar environments, but their core responsibilities differ significantly.
What are the key skills and qualifications needed to thrive as an assay development manager?
To thrive as an Assay Development Manager, you need a strong background in molecular biology, biochemistry, or a related field, typically with an advanced degree and experience in assay design and validation. Familiarity with laboratory automation, data analysis software, and quality management systems is essential, along with relevant certifications like GLP or ISO standards. Strong project management, leadership, and communication skills help drive cross-functional teams and ensure effective collaboration. These competencies are crucial for delivering reliable assays that meet scientific, regulatory, and business objectives.
What are the most commonly searched types of Assay Development jobs in Pennsylvania?
The most popular types of Assay Development jobs in Pennsylvania are:
What are popular job titles related to Assay Development Manager jobs in Pennsylvania?
For Assay Development Manager jobs in Pennsylvania, the most frequently searched job titles are:
What job categories do people searching Assay Development Manager jobs in Pennsylvania look for?
The top searched job categories for Assay Development Manager jobs in Pennsylvania are:
Full-time
Re-posted 6 days ago
Job description
Legend Biotech is seeking a Scientist as part of the Research & Development team based in Philadelphia, Pennsylvania.
Role Overview
We are seeking an initiative-taking and creative scientist to grow our pipeline efforts. The candidate will be part of Legend Biotech, a leading cell therapy company with a commercial CAR drug product CARVYKTI and an attractive pipeline portfolio. The candidate will be an integral part of our Philadelphia R&D team, whose aim is to research, develop and advance the next generation of cell therapies using innovative in vivo delivery technologies and create novel CAR therapy to treat a wide range of cancer and autoimmune disease indications. This position will focus on in-vivo CAR. The position requires enthusiasm, passion, outstanding skills in the art, diligence, and a desire to create new medicines for patients.
Expertise in immunology and/or oncology is required. The ideal candidate will be a highly motivated individual who enjoys fast paced biotech environment. You thrive in a collaborative work environment. Knowledge of state-of-art immunotherapy and its applications. As part of the Legend Biotech R&D team and under minimal supervision, you will be responsible for timely execution and delivery of projects in our discovery pipeline.
Key Responsibilities
- Design and optimize research with aims of exploring next generation cell therapies using in-vivo CAR-T.
- Contribute to project creation and formation through dissection of published literature to find novel solutions to in-vivo cell therapy problems.
- Isolate immune cells from leukopak or blood of healthy donors or patients and execute the evaluation of in-vivo CAR virus using a battery of in-vitro assays and in-vivo mice models.
- Perform treatment of solid tumor research requiring cell biology techniques including cell culture, transfection, FACS, and cell-based functional assays.
- Package and titer engineered viruses to infect immune cells in vitro and in vivo; Characterize virus particles with protein and PCR based assays; Measure transduction rate using flow and VCN analysis.
- Generate, manage, evaluate, and maintain critical data in a highly organized manner, including the use of ELN.
- Deliver result to meet timeline with accountability through presentation to a wide range of audiences of internal group meetings and other forums.
- Maintain compliance with GLP and EHS protocols.
Requirements
- PhD in Immunology or related discipline.
- 2 years of experience in the field of cell and gene therapy, in vivo CAR-T experience preferred.
- Extensive experience in immune cell-based analytics and assay development including but not limited to advanced multi-parameter flow-cytometry, immunogenicity assay such as cytotoxicity assay, cytokine release ELISA/MSD multiplex assays.
- Experience with lentivirus particle characterization and quantification using molecular (VCN) and flow-based assays.
- Experience with solid tumor models and in vivo cell-specific gene delivery is a plus.
- Track record of productivity is evidenced by publications or patents.
- Be able to work independently to plan and timely execute research projects
- Deep knowledge of immunology and immunotherapy; a deep understanding of solid tumor models is preferred
- Proficient in advanced gene delivery methods using LVV, VLP or LNP technologies
- Strong experience with lentivirus production, tittering and transduction.
- Working molecular biology and cellular biology knowledge in design and evaluation of modified viral vectors
- Strong multitasking, problem-solving and collaborative skills
Excellent verbal and written communication skills
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