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Area Director Clinical Operations Jobs (NOW HIRING)

Jade Biosciences

$215K - $240K/yr

Role Overview The Director, Clinical Operations will oversee the strategic and operational execution of clinical trials, leading cross-functional teams and collaborating with internal stakeholders ...

Doist

Director, Clinical Operations

Seattle, WA · On-site

$215K - $240K/yr

Role Overview The Director, Clinical Operations will oversee the strategic and operational execution of clinical trials, leading cross-functional teams and collaborating with internal stakeholders ...

TalentCraft

Director Clinical Operations

Yukon, OK · On-site

The Regional Director of Clinical Operations is responsible for overseeing site performance, revenue generation, and quality of research conducted. The Regional Director of Clinical Operations is ...

Doist

Director, Clinical Operations

Boston, MA · On-site

$215K - $240K/yr

Role Overview The Director, Clinical Operations will oversee the strategic and operational execution of clinical trials, leading cross-functional teams and collaborating with internal stakeholders ...

Doist

Director, Clinical Operations

San Francisco, CA · On-site

$215K - $240K/yr

Role Overview The Director, Clinical Operations will oversee the strategic and operational execution of clinical trials, leading cross-functional teams and collaborating with internal stakeholders ...

Socket.dev

Director, Clinical Operations

Cambridge, MA · On-site

... Director of Clinical Operations to lead the operational execution of an innovative early-stage clinical development program in Alzheimer's disease. This individual will play a critical role in ...

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Area Director Clinical Operations information

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How much do area director clinical operations jobs pay per year?

As of Sep 11, 2026, the average yearly pay for area director clinical operations in the United States is $145,969.00, according to ZipRecruiter salary data. Most workers in this role earn between $102,000.00 and $173,500.00 per year, depending on experience, location, and employer.

What does an area director clinical operations do?

An Area Director of Clinical Operations oversees the management and execution of clinical trials or healthcare operations across multiple sites within a specific region. They are responsible for ensuring that clinical activities comply with regulatory standards, maintaining high-quality patient care, managing budgets, and supporting clinical staff. Additionally, they play a key role in developing and implementing operational strategies, optimizing processes, and collaborating with other departments to achieve organizational goals.

How does an area director clinical operations typically support and collaborate with site managers and clinical teams across multiple locations?

As an Area Director of Clinical Operations, you play a pivotal role in bridging communication between executive leadership and clinical site teams. You will regularly collaborate with site managers to ensure clinical protocols are upheld, address operational challenges, and implement process improvements. Your responsibilities include conducting site visits, facilitating training, monitoring key performance metrics, and fostering a culture of compliance and patient-centered care. Building strong relationships with cross-functional teams is essential to streamline workflows and support the professional development of your teams.

What are the key skills and qualifications needed to thrive as an area director clinical operations, and why are they important?

To thrive as an Area Director of Clinical Operations, you need strong leadership abilities, comprehensive knowledge of clinical protocols, and typically a degree in nursing or healthcare administration, often complemented by several years of management experience. Familiarity with clinical management software, quality assurance systems, and regulatory compliance tools is essential, and certifications like CPHQ or an advanced nursing license can be advantageous. Excellent communication, strategic thinking, and conflict resolution skills help you effectively lead teams and drive operational improvements. These competencies are crucial for ensuring high-quality patient care, regulatory compliance, and efficient clinical operations across multiple sites.

What is the difference between Area Director Clinical Operations vs Clinical Operations Manager?

AspectArea Director Clinical OperationsClinical Operations Manager
Required CredentialsBachelor's or Master's in healthcare, life sciences, or related field; often with management experienceBachelor's or Master's in healthcare, life sciences, or related field; management experience preferred
Work EnvironmentOversees multiple sites or regions, strategic planning, high-level leadershipManages daily operations at a specific site or smaller region, focuses on team management
Employer & Industry UsagePharmaceutical companies, CROs, healthcare organizationsHospitals, clinics, research organizations, CROs

The main difference is that the Area Director Clinical Operations oversees multiple sites or regions with a focus on strategic leadership, while the Clinical Operations Manager handles daily operational management at a specific site or smaller area. Both roles require relevant healthcare or life sciences credentials, but the scope and level of responsibility differ.

What cities are hiring for Area Director Clinical Operations jobs?

Cities with the most Area Director Clinical Operations job openings:

What states have the most Area Director Clinical Operations jobs?

States with the most job openings for Area Director Clinical Operations jobs include:

What are popular job titles related to Area Director Clinical Operations jobs?

For Area Director Clinical Operations jobs, the most frequently searched job titles are:

Area Director Clinical Operations jobs near you

Director, Clinical Operations

On-site, Remote

Jade Biosciences
See more jobs at Jade Biosciencesexternal

$215K - $240K/yr

Full-time

Re-posted 14 days ago

Job description

About Jade Biosciences
Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases. Jade's lead candidate, JADE101, targets the cytokine APRIL, and is currently being evaluated in a Phase 1 clinical trial for the treatment of immunoglobulin A nephropathy. Jade's pipeline also includes JADE201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE301, an undisclosed antibody candidate, both currently in preclinical development. Jade was launched based on assets licensed from Paragon Therapeutics, an antibody discovery engine founded by Fairmount. For more information, visit JadeBiosciences.com and follow the Company on LinkedIn.
Role Overview
The Director, Clinical Operations will oversee the strategic and operational execution of clinical trials, leading cross-functional teams and collaborating with internal stakeholders and external vendors. This individual will manage trial budgets, vendor selection, and risk mitigation while contributing technical input to key clinical documents. This individual will also mentor staff, foster strong team and cross-functional relationships, and nimbly adapt in our dynamic organization. With proven leadership, financial acumen, and problem-solving skills, this individual will thrive in Jade's dynamic environment and evolve to support broader corporate initiatives. This is an exciting opportunity to make significant contributions to Jade's immunology pipeline, leading trials from first in human single site to global (APAC, LATAM, etc.) phase 3, as assigned.
Key Responsibilities
  • Performs role of Clinical Operations trial lead for assigned trials and leads cross-functional Study Execution Teams
  • Develops and executes trial operational strategies and partners cross-functionally to drive trial execution forward; provides strategic and technical recommendations to senior leadership
  • Directs the selection of CROs and other vendors (IxRS, Central Lab, ancillary/tech vendors), directs development of vendor Scopes of Work (SOW), scope changes, budgets, and vendor payments and partners with CROs and other vendors to deliver on study execution
  • Creates and tracks clinical trial budgets
  • Directs risk mitigation, escalation, and resolution activities both internally and with sites and vendors
  • Directs technical and strategic input into the development of clinical documents (protocols, monitoring plans, informed consent forms, investigator brochures, clinical study reports)
  • Builds relationships with clinical sites, vendors, and key stakeholders and maintains an understanding of the external landscape and adjusts plans accordingly
  • Represents Clinical Operations in cross-functional activities and supports development and management of the Clinical Operations function
  • Mentors more junior team members such as Clinical Trial Associates
  • Effectively builds strong internal teams and cross-functional relationships and demonstrates leadership and team building skills, along with success in proactive risk mitigation and problem solving
  • Flexible and creative in meeting the needs and challenges of a growing, dynamic company and demonstrates excellent problem-solving abilities
  • Strong financial acumen with outstanding track record of building budgets and managing expenses to budget
  • Contributes to corporate activities, including preparation of materials for Executive Team and Board of Director meeting materials

Qualifications
  • Bachelors + 15 years of related experience, or Masters + 12 years of related experience
  • 10+ years of clinical research experience, including 7+ years of trial management within a biopharmaceutical company; 5+ years within a small/startup company is a plus
  • Exceptional clinical trial management skills with a focus on strategic oversight of trial execution on time and on budget, study coordinator and/or site monitoring experience a plus
  • Extensive phase 1 through phase 3, global trial management experience
  • Immunology and/or rare disease trial management experience
  • Extensive experience selecting and managing vendors, including CROs, labs, IxRS, EDC, and ancillary technology/applications (e.g. eDiaries, eConsent, apps, etc)
  • Thorough knowledge and understanding of FDA and ICH Guidelines, GCP, medical terminology, and clinical trials
  • Detailed understanding of all aspects of clinical protocol design, implementation, IND/BLA/NDA submissions, and overall drug development
  • Experience managing, coaching, and mentoring personnel
  • Excellent communication, organizational, negotiation, and interpersonal skills with a strong reputation for collaboration

Position Location
This is a remote role; periodic travel to team and company events is required.
The anticipated salary range for candidates for this role is $215,000 - $240,000 The final salary offered will depend on several factors, which may include, but not limited to, relevant years of experience, educational background, and geography.
As part of the I-9 verification of authorization to work in the United States, Jade Bioscience participates in E-Verify. To learn more about E-Verify please review this poster.
Jade Biosciences is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

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