Application Scientist Jobs in California (NOW HIRING)

We imagine a world where new medicines reach patients in months, not years, and where scientific breakthroughs happen at the speed of thought.

Mithrl is building the world’s first commercially available AI Co‑Scientist. It is a discovery engine that transforms messy biological data into insights in minutes. Scientists ask questions in natural language, and Mithrl responds with real analysis, novel targets, hypotheses, and patent‑ready reports.

• 12X year‑over‑year revenue growth
• Trusted by leading biotechs and big pharma across three continents
• Driving real breakthroughs from target discovery to patient outcomes.

We are hiring an Application Scientist to help customers unlock the full value of the Mithrl AI Co‑Scientist and to produce high quality scientific assets that showcase the platform’s capabilities. This role requires a PhD level scientist with strong expertise in discovery biology, computational biology, or a related field, combined with excellent communication skills and a passion for working directly with customers and partners.

You will design and run analyses inside Mithrl, build publication‑quality narratives and figures, and support discovery programs across biomarker identification, target discovery, target validation, and early preclinical development. You will also work closely with AEs and sales teams to explain the scientific value of the platform and help convert prospects into successful customers.

This role sits between science, customer engagement, and product. You will surface gaps that prevent customers from achieving true bench‑to‑bench workflows and bring structured feedback into engineering and product. If you enjoy scientific storytelling, applied analysis, customer partnership, and working with cutting‑edge AI tools, you will thrive here.

• Produce publication quality analyses, case studies, whitepapers, and technical assets using Mithrl
• Support customers as they use Mithrl for biomarker discovery, target identification, target validation, and early preclinical studies
• Design and run analyses using the AI Co‑Scientist and help customers interpret results
• Represent Mithrl in scientific and customer facing meetings
• Surface issues that prevent customers from moving smoothly from analysis to decision making and share clear feedback with engineering and product
• Support AEs and sales teams with scientific expertise during calls, demos, workshops, and evaluations
• Create example analyses and workflows that showcase Mithrl’s value to prospective customers
• Provide scientific training, onboarding, and best practice guidance for new users
• Collaborate with marketing on scientific content for conferences, events, and digital materials
• Act as a subject matter expert on discovery workflows and how Mithrl supports them end to end

Required Qualifications

• PhD in biology, computational biology, bioinformatics, pharmacology, or a closely related field
• Strong expertise in discovery and preclinical development
• Ability to interpret multi modal biological data and produce high quality analyses
• Strong publication record or equivalent scientific writing and visualization experience
• Excellent communication and presentation skills for both scientific and non scientific audiences
• Ability to collaborate with sales teams and support product demonstrations with scientific credibility
• Comfort working directly with customers and supporting their scientific workflows
• Ability to translate complex scientific concepts into clear and actionable narratives

Nice to Have

• Experience using AI based, computational, or informatics platforms in discovery
• Experience with biomarker research, target discovery, or translational biology
• Experience in a customer facing scientific role such as application scientist, scientific liaison, or consulting scientist
• Familiarity with enrichment analysis, pathway interpretation, or similar analytic workflows
• Experience creating scientific content for marketing or conferences

• You will see your scientific work influence customer success, product strategy, and brand credibility
• Team: Join a tight‑knit, talent‑dense team of engineers, scientists, and builders
• Culture: We value consistency, clarity, and hard work. We solve hard problems through focused daily execution
• Speed: We ship fast (2x/week) and improve continuously based on real user feedback
• Location: Beautiful SF office with a high‑energy, in‑person culture
• Benefits: Comprehensive PPO health coverage through Anthem (medical, dental, and vision) + 401(k) with top‑tier plans

We encourage you to apply even if you do not believe you meet every single qualification. Not all strong candidates will meet every single qualification as listed. Research shows that people who identify as being from underrepresented groups are more prone to experiencing imposter syndrome and doubting the strength of their candidacy, so we urge you not to exclude yourself prematurely and to submit an application if you're interested in this work. We think AI systems like the ones we're building have enormous social and ethical implications. We think this makes representation even more important, and we strive to include a range of diverse perspectives on our team.