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Analytical Method Development Scientist Jobs in California

Russell Tobin

Analytical Scientist

San Diego, CA

$40 - $45/hr

Maintain detailed experimental documentation and analyze/present scientific data * Assist with SOPs, technical reports, and analytical method development Qualifications * BS/MS in Biology, Immunology ...

Aequor

Senior Analytical Chemist

Thousand Oaks, CA · On-site

Senior Scientist with UHPLC, GC, Karl Fisher, Method Development and Small Molecules Experience ... Perform method development to deliver to the analytical control strategy for our small molecule ...

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How much do analytical method development scientist jobs pay per hour?

As of Jun 16, 2026, the average hourly pay for analytical method development scientist in California is $41.53, according to ZipRecruiter salary data. Most workers in this role earn between $31.06 and $47.93 per hour, depending on experience, location, and employer.

What does an Analytical Method Development Scientist do?

An Analytical Method Development Scientist is responsible for designing, developing, and validating analytical methods used to test and analyze chemical compounds, pharmaceuticals, or other materials. They ensure that the methods are accurate, reliable, and compliant with regulatory standards. This role involves working with advanced laboratory instruments, troubleshooting analytical issues, and documenting procedures for use in research, quality control, or manufacturing environments.

What are the key skills and qualifications needed to thrive as an Analytical Method Development Scientist, and why are they important?

To thrive as an Analytical Method Development Scientist, a strong background in chemistry, analytical techniques, and method validation—often supported by a relevant degree in chemistry or pharmaceutical sciences—is essential. Familiarity with laboratory instrumentation such as HPLC, GC, MS, and software for data analysis, as well as knowledge of regulatory guidelines like ICH and FDA, is typically required. Attention to detail, problem-solving abilities, and effective communication are vital soft skills for success in this role. These skills ensure reliable method development, regulatory compliance, and effective collaboration within multidisciplinary scientific teams.

What are the typical challenges faced by an Analytical Method Development Scientist when transferring methods to quality control or manufacturing teams?

One common challenge for Analytical Method Development Scientists is ensuring that newly developed analytical methods are robust and reproducible when transferred to quality control or manufacturing teams. Differences in equipment, sample matrices, or operator technique can impact results, so thorough method validation and clear documentation are essential. Scientists often work closely with cross-functional teams to provide training, troubleshoot issues, and adapt protocols as needed. Successfully managing these transitions helps maintain product quality and regulatory compliance.

What is the difference between Analytical Method Development Scientist vs Analytical Chemist?

AspectAnalytical Method Development ScientistAnalytical Chemist
Primary FocusDeveloping and validating new analytical methodsPerforming routine analysis and testing
Work EnvironmentResearch labs, R&D departmentsQuality control labs, manufacturing facilities
CredentialsBachelor's or Master's in Chemistry or related field; experience in method developmentBachelor's degree in Chemistry or related field; experience in analytical testing

While both roles involve analytical testing, the Analytical Method Development Scientist primarily focuses on creating and validating new analytical methods, often in research settings. In contrast, the Analytical Chemist typically performs routine testing to ensure product quality in manufacturing or quality control labs.

What are popular job titles related to Analytical Method Development Scientist jobs in California? For Analytical Method Development Scientist jobs in California, the most frequently searched job titles are:
What job categories do people searching Analytical Method Development Scientist jobs in California look for? The top searched job categories for Analytical Method Development Scientist jobs in California are:
Analytical Method Development Scientist jobs near you
Infographic showing various Analytical Method Development Scientist job openings in California as of June 2026, with employment types broken down into 67% Full Time, and 33% Contract. Highlights an 100% In-person job distribution, with an average salary of $86,373 per year, or $41.5 per hour.

Chemist / Senior Chemist - Analytical Method Development

Programmable Medicine Operatin

Redwood City, CA • On-site

$95K - $128K/yr

Full-time

Medical, Dental, Vision

Posted 12 days ago

Job description

Programmable Medicine, a clinical stage biopharmaceutical company located in Redwood City, is seeking a motivated Chemist/Sr. Chemist Analytical Method Development. We are focused on developing novel nanomedicines, HD therapeutics (HDTs), to treat unmet medical needs in ophthalmology, neurology, inflammatory diseases, and neuro-oncology. Our HD platform builds therapeutics that are selectively taken up only by inflamed tissues, allowing us to treat diseases with unprecedented precision.
This position reports to the Director, Analytical Research and Development and will manage develop analytical methods and test various drug substances and drug products to support Medicinal Chemistry, Translational, Manufacturing, and CDMOs. The successful candidate will be part of a dynamic, interdisciplinary team and require a high degree of creativity and initiative. This is an exciting opportunity to help drive the development of novel therapies for unmet medical needs in multiple indications.
The Position
The Chemist / Senior Chemist Analytical Method Development will serve as a key member of our development team, working on-site full-time, in our Redwood City laboratory, focusing on novel early and late-phase programs.
Duties and Responsibilities - Essential Functions
• Manage stability study and trend analysis such as design/review stability studies, prepare/review protocols, and monitor ongoing stability studies in-house and at various CDMOs
. Develop various analytical methods.
• Test various drug substance/drug product samples.
• Manage, set up, and maintain all instruments in the analytical lab.
• Keep and accurately maintain detailed electronic laboratory notebooks.
• Perform tasks per protocols as required.
• Additional responsibilities may be added as required.
Job Requirements
• BS degree in Chemistry, Analytical Chemistry, or closely related scientific area is required along with a minimum of 5 years of pharmaceutical industry experience.
• In-depth expertise with stability study, analytical method development and validation with HPLC, UPLC.
• Expertise in HPLC, HPLC/UPLC, LC-MS, SEC, and ICP-MS analytical techniques is preferred.
• Prior experience with analytical method development and validation for small molecule drugs.
• Experience with analytical method development and various tests for polymer-drug conjugates and/or biologics drug candidates are preferred.
• Experience with injectable and oral dosage forms
• Independent, problem-solving, and troubleshooting skills.
• Knowledge of GLP & GMP requirements
• Well organized and self-directed
• Ability to communicate scientific findings and recommendations in one-on-one discussions, departmental meetings, and prepare reports.
• Ability to work in a fast-paced, dynamic environment with multiple projects and priorities.
• Must be able to work on site at our Redwood City facility, five days per week.
About Programmable Medicine
This is a unique opportunity to join a team focused on the development of a new class of precision medicines that selectively treat diseased cells in regions of inflammation. By making precision medicine even more precise, our nanomedicine technology has the potential to change the standard of care across ophthalmology, neurology, inflammatory diseases and neuro-oncology. You will have the opportunity to learn new skills and gain a better understanding of cutting-edge technology.
We have a comprehensive compensation package including fully paid medical, dental and vision benefits for you and your family. We want our employees to become shareholders and offer new hire stock options. The company also offers participation in the annual bonus program. The salary range for MS candidates located in the Bay Area, with a minimum of 8 years of industry experience is $95,000 - $128,000, depending on years of experience and relevant skill sets.

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