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Analytical Method Development Job Jobs (NOW HIRING)

Eurofins

Bioassay Method Development

Indianapolis, IN · On-site

... Development and Manufacturing Organisations. It also has a rapidly developing presence in highly ... Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety ...

Actalent

Analytical Chemist

Hercules, CA

$30 - $35/hr

Analytical Chemist (Method Development & Validation) Overview We are seeking a highly skilled Analytical Chemist to support complex drug substance and drug product programs in a regulated laboratory ...

Actalent

Analytical Chemist

Hercules, CA · On-site

$30 - $35/hr

Analytical Chemist (Method Development & Validation) Overview We are seeking a highly skilled Analytical Chemist to support complex drug substance and drug product programs in a regulated laboratory ...

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Analytical Method Development Job information

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$89K

$191.4K

$287.5K

How much do analytical method development job jobs pay per year?

As of Jun 4, 2026, the average yearly pay for analytical method development job in the United States is $191,412.00, according to ZipRecruiter salary data. Most workers in this role earn between $94,000.00 and $249,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in an Analytical Method Development role, and why are they important?

To thrive in Analytical Method Development, you need a strong background in chemistry or pharmaceutical sciences, experience with analytical techniques, and often at least a bachelor's or master's degree in a related field. Familiarity with instruments such as HPLC, GC, LC-MS, and relevant software, as well as knowledge of regulatory guidelines like ICH and USP, are typically required. Attention to detail, problem-solving abilities, and effective communication are standout soft skills for this position. These competencies ensure the development of robust, reliable analytical methods essential for product quality, regulatory compliance, and successful project outcomes.

What are some common challenges faced when developing new analytical methods in a laboratory setting?

Professionals in Analytical Method Development often encounter challenges such as selecting appropriate instrumentation, optimizing method parameters for accuracy and precision, and ensuring reproducibility across different sample matrices. Additionally, troubleshooting unexpected results and adapting methods to comply with regulatory standards can be complex and time-consuming. Strong collaboration with quality assurance, production, and research teams is essential to address these challenges efficiently and to ensure that developed methods are robust and validated for routine use.

What is analytical method development?

Analytical method development is the process of creating and optimizing procedures to accurately measure and analyze chemical, physical, or biological properties of substances. This work is essential in industries like pharmaceuticals, environmental testing, and food safety to ensure products meet quality and regulatory standards. Professionals in this field design, validate, and troubleshoot analytical techniques such as chromatography, spectroscopy, and titration. Their efforts help guarantee reliable and reproducible results for research, manufacturing, and quality control.

What is the difference between Analytical Method Development Job vs Analytical Method Validation Job?

AspectAnalytical Method Development JobAnalytical Method Validation Job
Primary FocusDesigning and developing new analytical methodsVerifying and validating existing methods for accuracy and reliability
Required SkillsMethod optimization, experimental design, troubleshootingValidation protocols, compliance, documentation
Work EnvironmentResearch labs, R&D departmentsQuality control labs, regulatory compliance settings

While both roles involve analytical techniques, the Analytical Method Development Job focuses on creating new methods, whereas the Analytical Method Validation Job ensures those methods meet regulatory standards. Understanding these differences helps professionals target their skills and career paths effectively.

Infographic showing various Analytical Method Development Job job openings in the United States as of May 2026, with employment types broken down into 1% Locum Tenens, 83% Full Time, 8% Part Time, and 8% Contract. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $191,412 per year, or $92 per hour.

Principal Scientist, Method Development & Validation

Bachem

Vista, CA • On-site

$131.25K - $180.46K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 18 days ago

Job description

A brief overview The Principal Scientist, Method Development & Validation will fulfill a critical role in QC GMP operations. This individual helps to guide development of release/stability and in-process analytical methods for all peptide drug substances/finish products and raw materials at Bachem America sites. The individual will work closely together mainly with process development, production manufacturing, QC material testing, QC IPC, and QC API testing to understand and align analytical strategies. This individual will support method development, validation, and method transfer, including authoring technical quality documents (method, protocols, reports, etc.), execution of protocols and review of data and technical documents. In addition, this individual performs special projects such as peptide characterization, impurity identification, and other special studies as necessary. This individual conducts or contributes to investigations and the identification and implementation of corrective actions. This individual contributes to advances in analytical capabilities and innovations for the Quality Control department. This individual proactively provides solutions to resolve analytical challenges to support our internal and external customers in a timely manner. The individual should ultimately define and implement best practices within QC. What you will do
  • Independently design and implement advanced analytical methods and control strategies for peptide API and raw material testing using techniques such as HPLC, UPLC, LC-MS, GC-MS, SEC, KF, and others as needed
  • Independently plan and execute validation studies for test methods
  • Implement and perform analytical method transfer to Quality Control Department
  • Write validation protocols and final reports, test methods, standard operating procedures, and technical reports
  • Provide guidance and training to junior MDV Scientists, peers and Quality Control analysts
  • Routinely work with hazardous materials and manage hazardous waste in a satellite accumulation area
  • Build or expand the analytical capabilities as needed.
  • Recommend and implement improvements to methods, laboratory operations and assist in evaluating the need of any potential equipment for analytical purposes.
  • Independently conduct and document investigations related to validation activities
  • Contribute to GMP systems improvement
  • Develop and maintain in-depth understanding of the scientific principles associated with analytical methods being developed, optimized, transferred, validated, and qualified
Qualifications
  • B.S. in chemistry or related scientific field with 15+ years' industry experience
  • M.S. in chemistry or related scientific field with 15+ years' industry experience
  • Ph.D. in chemistry or related scientific field with 12+ years' industry experience (preferred)
  • 3+ years' experience in a GMP environment
  • 10+ years' experience in Method Development & Validation: extensive hands-on experience in method development, optimization, and validation of methods using the following instrumentation: LC-MS, UPLC, HPLC, GC-MS, MS-MS, KF and other routine Analytical methodologies in a deadline driven environment.
  • Experience with Peptides (preferred)
  • 10+ years' experience with ICH, FDA, USP, and GMP/GLP standards.
  • 10+ years' experience independently analyzing complex data, identification of trends, and resolution of technical issues in routine testing.
  • 7+ years' experience in Technical Leadership & Reporting: Serve as a project SME, providing analytical support to internal and external customers.
  • Experience with use of Master Control or Veeva (preferred)
  • Extensive hands-on experience with HPLC (SEC, IC)/UPLC, GC, KF, Amino Acid Analysis, MS, MS/MS sequencing and LC-MS.
  • Extensive experience in troubleshooting instrumentation and training others and implementation of best practices.
  • Experience in writing standard operating procedures (SOPs), test methods, technical protocols, reports and other documents in compliance with GMP/GLP
  • Excellent written and oral communication skills
  • Ability to effectively organize, multitask, and work in a fast-paced, timeline driven work environment.
  • Experience in evaluation and implementation of innovation projects (new test strategies, automation, instrumentation, etc)
  • Ability to coordinate work with other functions/departments to achieve project objectives.
  • Ability to provide expertise to management, technical project leaders, project/program leaders on method feasibility and risk assessment.
Base salary range: $131,246 - $180,463 Placement of new hires in this wage range is based on several factors including education, skill sets, experience, and training. Total Rewards We offer all Team Members a total rewards package including competitive pay, annual performance bonus, a generous benefit package with comprehensive Medical/Dental/Vision coverage, 401(k) plan with employer contribution, and paid vacation, personal and sick days. Corporate Social Responsibility Bachem takes responsibility for future generations by a careful handling of resources and avoiding environmental risks. We continually improve our ecological performance and develop and implement new approaches for enhancing employees' environmental awareness. EcoVadis has awarded Bachem Gold Medal status in their assessment of Bachem. Bachem Americas is an Equal Opportunity Employer As an equal opportunity employer, we celebrate the diversity of our team and are committed to building an inclusive workplace where individuals are hired and advanced based on merit, skills, and qualifications. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status, or other legally protected status. At Bachem, you'll find a diverse, multicultural team. The (a) in the job title stands for all. We welcome applications from all candidates. What matters are your skills and motivation-regardless of age, gender, background, religion, or sexual orientation. Please note: unsolicited resumes from recruitment agencies will not be considered. Share this job posting by email

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