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$89K

$191.4K

$287.5K

How much do analytical method development job jobs pay per year?

As of Jun 4, 2026, the average yearly pay for analytical method development job in the United States is $191,412.00, according to ZipRecruiter salary data. Most workers in this role earn between $94,000.00 and $249,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in an Analytical Method Development role, and why are they important?

To thrive in Analytical Method Development, you need a strong background in chemistry or pharmaceutical sciences, experience with analytical techniques, and often at least a bachelor's or master's degree in a related field. Familiarity with instruments such as HPLC, GC, LC-MS, and relevant software, as well as knowledge of regulatory guidelines like ICH and USP, are typically required. Attention to detail, problem-solving abilities, and effective communication are standout soft skills for this position. These competencies ensure the development of robust, reliable analytical methods essential for product quality, regulatory compliance, and successful project outcomes.

What are some common challenges faced when developing new analytical methods in a laboratory setting?

Professionals in Analytical Method Development often encounter challenges such as selecting appropriate instrumentation, optimizing method parameters for accuracy and precision, and ensuring reproducibility across different sample matrices. Additionally, troubleshooting unexpected results and adapting methods to comply with regulatory standards can be complex and time-consuming. Strong collaboration with quality assurance, production, and research teams is essential to address these challenges efficiently and to ensure that developed methods are robust and validated for routine use.

What is analytical method development?

Analytical method development is the process of creating and optimizing procedures to accurately measure and analyze chemical, physical, or biological properties of substances. This work is essential in industries like pharmaceuticals, environmental testing, and food safety to ensure products meet quality and regulatory standards. Professionals in this field design, validate, and troubleshoot analytical techniques such as chromatography, spectroscopy, and titration. Their efforts help guarantee reliable and reproducible results for research, manufacturing, and quality control.

What is the difference between Analytical Method Development Job vs Analytical Method Validation Job?

AspectAnalytical Method Development JobAnalytical Method Validation Job
Primary FocusDesigning and developing new analytical methodsVerifying and validating existing methods for accuracy and reliability
Required SkillsMethod optimization, experimental design, troubleshootingValidation protocols, compliance, documentation
Work EnvironmentResearch labs, R&D departmentsQuality control labs, regulatory compliance settings

While both roles involve analytical techniques, the Analytical Method Development Job focuses on creating new methods, whereas the Analytical Method Validation Job ensures those methods meet regulatory standards. Understanding these differences helps professionals target their skills and career paths effectively.

Infographic showing various Analytical Method Development Job job openings in the United States as of May 2026, with employment types broken down into 1% Locum Tenens, 83% Full Time, 8% Part Time, and 8% Contract. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $191,412 per year, or $92 per hour.

Chemist / Senior Chemist - Analytical Method Development

Programmable Medicine Operatin

Redwood City, CA • On-site

$95K - $128K/yr

Full-time

Medical, Dental, Vision

Posted 4 hours ago

Job description

Programmable Medicine, a clinical stage biopharmaceutical company located in Redwood City, is seeking a motivated Chemist/Sr. Chemist Analytical Method Development. We are focused on developing novel nanomedicines, HD therapeutics (HDTs), to treat unmet medical needs in ophthalmology, neurology, inflammatory diseases, and neuro-oncology. Our HD platform builds therapeutics that are selectively taken up only by inflamed tissues, allowing us to treat diseases with unprecedented precision.
This position reports to the Director, Analytical Research and Development and will manage develop analytical methods and test various drug substances and drug products to support Medicinal Chemistry, Translational, Manufacturing, and CDMOs. The successful candidate will be part of a dynamic, interdisciplinary team and require a high degree of creativity and initiative. This is an exciting opportunity to help drive the development of novel therapies for unmet medical needs in multiple indications.
The Position
The Chemist / Senior Chemist Analytical Method Development will serve as a key member of our development team, working on-site full-time, in our Redwood City laboratory, focusing on novel early and late-phase programs.
Duties and Responsibilities - Essential Functions
• Manage stability study and trend analysis such as design/review stability studies, prepare/review protocols, and monitor ongoing stability studies in-house and at various CDMOs
. Develop various analytical methods.
• Test various drug substance/drug product samples.
• Manage, set up, and maintain all instruments in the analytical lab.
• Keep and accurately maintain detailed electronic laboratory notebooks.
• Perform tasks per protocols as required.
• Additional responsibilities may be added as required.
Job Requirements
• BS degree in Chemistry, Analytical Chemistry, or closely related scientific area is required along with a minimum of 5 years of pharmaceutical industry experience.
• In-depth expertise with stability study, analytical method development and validation with HPLC, UPLC.
• Expertise in HPLC, HPLC/UPLC, LC-MS, SEC, and ICP-MS analytical techniques is preferred.
• Prior experience with analytical method development and validation for small molecule drugs.
• Experience with analytical method development and various tests for polymer-drug conjugates and/or biologics drug candidates are preferred.
• Experience with injectable and oral dosage forms
• Independent, problem-solving, and troubleshooting skills.
• Knowledge of GLP & GMP requirements
• Well organized and self-directed
• Ability to communicate scientific findings and recommendations in one-on-one discussions, departmental meetings, and prepare reports.
• Ability to work in a fast-paced, dynamic environment with multiple projects and priorities.
• Must be able to work on site at our Redwood City facility, five days per week.
About Programmable Medicine
This is a unique opportunity to join a team focused on the development of a new class of precision medicines that selectively treat diseased cells in regions of inflammation. By making precision medicine even more precise, our nanomedicine technology has the potential to change the standard of care across ophthalmology, neurology, inflammatory diseases and neuro-oncology. You will have the opportunity to learn new skills and gain a better understanding of cutting-edge technology.
We have a comprehensive compensation package including fully paid medical, dental and vision benefits for you and your family. We want our employees to become shareholders and offer new hire stock options. The company also offers participation in the annual bonus program. The salary range for MS candidates located in the Bay Area, with a minimum of 8 years of industry experience is $95,000 - $128,000, depending on years of experience and relevant skill sets.

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