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3D Tissue Model Jobs (NOW HIRING)

Senior Scientist - Tissue Engineering

Portland, OR · On-site

$97K - $132K/yr

Build placental development models: Establish and optimize co-culture systems integrating ... Demonstrated expertise in tissue engineering and 3D culture system development * Experience ...

Senior Scientist

San Francisco, CA

$107K - $147K/yr

Responsibilities Tissue Model Development * Lead development and optimization of complex in vitro human tissue models using primary human cells and advanced 3D culture systems. * Design, execute, and ...

The Opportunity The Tissue Models team is dedicated to developing advanced in vitro systems that ... Hands-on experience with 3D culture model development * Familiarity with standard molecular biology ...

... tissue models for therapeutic discovery and translational research. This role is ideal for a highly ... Experience working with primary human cells and/or 3D cell culture systems such as organoids ...

Senior Scientist

San Francisco, CA · On-site

$107K - $147K/yr

Responsibilities Tissue Model Development * Lead development and optimization of complex in vitro human tissue models using primary human cells and advanced 3D culture systems. * Design, execute, and ...

... tissue models for therapeutic discovery and translational research. This role is ideal for a highly ... Experience working with primary human cells and/or 3D cell culture systems such as organoids ...

The Opportunity The Tissue Models team is dedicated to developing advanced in vitro systems that ... Hands-on experience with 3D culture model development * Familiarity with standard molecular biology ...

Postdoctoral Appointee

Bloomington, IN · On-site

$45K - $61K/yr

Ability to perform cell culture and tissue models such as 3D tissue models and microfluidic systems to simulate microgravity. e. Understanding and experience with oxidative stress and mitochondrial ...

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3D Tissue Model information

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How much do 3d tissue model jobs pay per hour?

As of Jun 5, 2026, the average hourly pay for 3d tissue model in the United States is $35.05, according to ZipRecruiter salary data. Most workers in this role earn between $25.48 and $41.59 per hour, depending on experience, location, and employer.

What are 3D tissue models?

3D tissue models are laboratory-created structures that mimic the architecture and function of human tissues more accurately than traditional two-dimensional cell cultures. These models are used in biomedical research to study disease mechanisms, drug responses, and tissue development. By providing a more realistic environment for cells, 3D tissue models enhance the relevance of experimental results and can reduce the need for animal testing. They are widely used in areas such as cancer research, toxicology, and regenerative medicine.

What are the key skills and qualifications needed to thrive as a 3D Tissue Model Scientist, and why are they important?

To thrive as a 3D Tissue Model Scientist, you need a solid background in cell biology, tissue engineering, and molecular biology, typically supported by a relevant advanced degree such as a Master's or Ph.D. Proficiency in laboratory techniques, 3D bioprinting systems, imaging technologies, and data analysis software is crucial. Strong analytical thinking, problem-solving abilities, and effective teamwork and communication skills enable you to design, troubleshoot, and optimize complex tissue models. These skills are essential to accurately replicate physiological environments, drive innovative research, and contribute to advancements in drug discovery and regenerative medicine.

What are some common challenges faced when working as a 3D Tissue Model researcher, and how can they be addressed?

One common challenge in a 3D Tissue Model researcher role is ensuring model reproducibility and consistency across experiments, as even small variations in cell sourcing or scaffold composition can affect results. Researchers often address this by rigorously standardizing protocols and collaborating closely with multidisciplinary teams, including bioengineers and biologists, to validate findings. Additionally, keeping up with rapidly evolving technologies and integrating new methods—such as bioprinting or advanced imaging—can be demanding but also offers significant opportunities for professional growth and innovation.

What is the difference between 3D Tissue Model vs 3D Cell Culture Specialist?

Aspect3D Tissue Model3D Cell Culture Specialist
CredentialsTypically requires a degree in biology, biomedical engineering, or related fieldsSimilar educational background, often with specialized training in cell culture techniques
Work EnvironmentResearch labs, biotech companies, academic institutions focusing on tissue engineeringLaboratories, biotech firms, research centers working on cell culture and tissue development
Industry UsageUsed in regenerative medicine, drug testing, and disease modelingApplied in cell therapy, drug screening, and tissue research

While both roles involve working with 3D biological systems, a 3D Tissue Model focuses on creating complex tissue-like structures for research and testing, whereas a 3D Cell Culture Specialist primarily handles the cultivation of cells in three-dimensional environments for various applications.

Infographic showing various 3D Tissue Model job openings in the United States as of May 2026, with employment types broken down into 92% Full Time, and 8% Contract. Highlights an 100% In-person job distribution, with an average salary of $72,895 per year, or $35 per hour.

Senior Scientist - Tissue Engineering

e184

Portland, OR • On-site

$97K - $132K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 27 days ago


Job description

About us

e184 Artificial Womb is a biotechnology research company dedicated to advancing ectogenesis - the ability to support human development outside the body - to expand reproductive freedom and redefine what is possible in medicine. Our mission is to remove the biological constraints that limit who can safely carry a pregnancy, enabling new pathways to parenthood for individuals facing medical risk, infertility, or physiological barriers to gestation.

We operate at the intersection of biology, engineering, and computational science, building integrated platforms that combine advanced tissue models, adaptive culture systems, and automated experimental workflows to understand and recreate the conditions required for healthy human gestation beyond the uterus.

Role overview

As a Senior Scientist at e184 Artificial Womb, you will lead the development of engineered tissue systems designed to support placental development through controlled vascularization and maternal-fetal interface modeling. Your work will focus on building vascularized culture platforms that integrate trophoblast stem cell models, placental organoids, and endothelial cells to recreate the structural and signaling environments required for placental formation and function.

You will drive experimental strategy from system design through biological validation, working closely with developmental biologists, biomaterials scientists, and engineering teams to translate principles of tissue engineering into functional platforms for ex utero gestation. This is a highly hands-on leadership role for a scientist experienced in vascularized tissue models who is excited to work at the intersection of tissue engineering and developmental biology in a fast-moving startup environment where engineered systems directly enable biological discovery.
What youll do
  • Engineer vascularized tissue systems: Design and develop platforms that promote formation and maturation of engineered vasculature to support placental tissue development and function.

  • Build placental development models: Establish and optimize co-culture systems integrating trophoblast stem cells, placental organoids, and endothelial cells to model maternal-fetal interface biology.

  • Guide vascular patterning and function: Develop strategies to control angiogenesis, perfusion, and endothelial-trophoblast interactions that drive tissue organization and nutrient exchange.

  • Integrate biomaterials and perfusion systems: Collaborate with biomaterials and engineering teams to incorporate hydrogels, scaffolds, and perfusion interfaces that enable long-term tissue viability.

  • Characterize tissue structure and function: Apply imaging, histology, molecular profiling, and functional assays to evaluate vascular development, trophoblast differentiation, and placental maturation.

  • Drive iterative platform development: Translate biological outcomes into engineering improvements through rapid experimental iteration and cross-disciplinary collaboration.

Core requirements
  • PhD in Tissue Engineering, Bioengineering, Biomedical Engineering, Developmental Biology, or a related field with postdoctoral experience, or 7+ years of relevant industry or academic experience

  • Demonstrated expertise in tissue engineering and 3D culture system development

  • Experience engineering or studying vascularized tissues or angiogenesis in vitro

  • Hands-on experience with mammalian cell culture and complex co-culture systems

  • Strong understanding of endothelial biology and vascular development

  • Experience designing and executing independent experimental programs

  • Ability to lead technically complex projects in interdisciplinary environments

  • Strong organizational and documentation skills

  • Comfort working in a fast-paced, iterative startup environment

Youll stand out with
  • Experience working with trophoblast stem cells, placental organoids, or placental biology models

  • Expertise in vascular patterning, perfusion culture, or microvascular engineering

  • Experience integrating engineered tissues with biomaterials or hydrogel systems

  • Hands-on histology and advanced imaging experience for 3D tissue characterization

  • Experience with angiogenic signaling pathways and endothelial-epithelial interactions

  • Familiarity with microfluidic or perfusion-based tissue culture platforms

  • Experience translating engineered tissue models into functional biological systems

  • Prior startup or early-stage technology development experience

Why e184?
  • Unrivaled impact: Your work directly enables technology that transforms human fertility and reproductive medicine.

  • Full-spectrum growth: Gain exposure to the entire lifecycle of discovery. From screening to mechanistic validation.

  • Best of both worlds: Experience the creative chaos of an early-stage startup with the stability of a well-capitalized company.

  • Elite collaboration: Work alongside a world-class team who are as driven as you are.

What we offer
  • Competitive salary + equity participation is considered

  • State-of-the-art facility in Portland metro area

  • Comprehensive Medical, Dental, Vision, and 401(k) with company match

  • 20 days PTO + 11 paid holidays

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
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