Using human iPSC-derived cardiac organoids, genetically engineered mouse models, CRISPR technologies, and single-cell/multi-omics approaches, we investigate the molecular regulation of heart ...
Using human iPSC-derived cardiac organoids, genetically engineered mouse models, CRISPR technologies, and single-cell/multi-omics approaches, we investigate the molecular regulation of heart ...
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Post Doctoral Scientist - Cardiovascular Development
Columbus, OH • On-site
Full-time
Posted 5 days ago
Nationwide Children's Hospital rating
7.0
Based on 130 frontline employees who took The Breakroom Quiz
493rd of 1,023 rated hospitals
Job description
Dr. Jihyun Jang at Nationwide Children's Hospital and The Ohio State University is seeking a Fellow to study how epitranscriptomic mechanisms regulate cardiac development and congenital heart disease. Our research focuses on m6A RNA methylation and its roles in developmental cell fate decisions, congenital heart defects, and pediatric cardiomyopathies. Using human iPSC-derived cardiac organoids, genetically engineered mouse models, CRISPR technologies, and single-cell/multi-omics approaches, we investigate the molecular regulation of heart development and disease. Projects include ventricular development, congenital valve disease, endocardial biology, and pediatric cardiomyopathy. Read more about the lab here: Jihyun Jang
Job Description Summary:
Conducts research, designs experiments, analyzes data, and presents findings under the mentorship of an established RI principal investigator or Senior Research Scientists. Appointment is a maximum of 7 years in length.
Job Description:
Essential Functions:
- Designs experiments, develops protocols, and conducts research under the guidance of a faculty mentor.
- Assists in the training and supervision of technical support staff in performing specific techniques essential to carrying out the research program.
- Records and analyzes data generated by the research study. Assists in the development of hypotheses for further investigation from the results of the studies performed.
- Assists with the preparation of scientific and technical papers for publication in peer-reviewed journals. Presents findings at local and national research forums.
- Collaborates with other ongoing research efforts either at NCH or at The Ohio State University.
- Works toward research independence, preparing to submit proposals to and obtain funding from external granting agencies.
Education Requirement:
PhD or equivalent degree in relevant field of science, required.
Licensure Requirement:
(not specified)
Certifications:
(not specified)
Skills:
- Effective interpersonal skills required in interactions with scientists, physicians, and laboratory colleagues.
- Excellent laboratory technical skills.
- Excellent computer skills.
- Skills in qualitative and quantitative research methods.
- Ability to proactively manage and drive projects.
Experience:
Research experience from PhD program, required.
Physical Requirements:
OCCASIONALLY: Bend/twist, Climb stairs/ladder, Lifting / Carrying: 11-20 lbs
FREQUENTLY: Lifting / Carrying: 0-10 lbs, Standing, Walking
CONTINUOUSLY: Audible speech, Color vision, Computer skills, Decision Making, Depth perception, Flexing/extending of neck, Hand use: grasping, gripping, turning, Hearing acuity, Interpreting Data, Peripheral vision, Problem solving, Reaching above shoulder, Repetitive hand/arm use, Seeing - Far/near, Sitting, Squat/kneel
Additional Physical Requirements performed but not listed above:
Pressure in this position will vary depending on the workload. The workload will be heavy but manageable most of the time. Pressure may arise in the face of deadlines associated research and manuscript writing.
"The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the individuals so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under their supervision. EOE M/F/Disability/Vet"
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About Nationwide Children's Hospital
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Nationwide Children's Hospital, established in 1894, is a leading pediatric healthcare system based in Columbus, Ohio, United States. They serve as a primary pediatric network, providing wellness, preventive, diagnostic, treatment, and rehabilitative care for infants, children, adolescents, and adults with congenital disease. Being the third-largest pediatric hospital in the nation, Nationwide Children's Hospital prides itself on its relentless commitment to children and their families, driven by their core values of respect, integrity, determination, empathy, and solidarity. The institution's comprehensive mission is to enhance the health of children by providing high-quality, family-centered care, conducting groundbreaking research, advocating for pediatric health, and training top healthcare professionals.
Industry
Hospitals
Company size
10,000+ Employees
Headquarters location
Columbus, OH, US
Year founded
1892