ZipRecruiter

Log In

Bighat

58 Bighat Jobs Hiring Near You

BigHat Biosciences

Automation Engineer II

San Mateo, CA · On-site

$150K - $168K/yr

BigHat Biosciences is seeking a hands-on Automation Engineer to build, support, and sustain the automated workflows that power our high-throughput antibody production and characterization platform.

BigHat

SharePoint Consultant

San Mateo, CA · On-site

$138 - $234/hr

BigHat Biosciences is looking for an experienced and detail-oriented SharePoint Development Consultant to support the design, build-out, and configuration of SharePoint-based program management ...

BigHat Biosciences

SharePoint Consultant

San Mateo, CA · On-site +1

BigHat Biosciences is looking for an experienced and detail-oriented SharePoint Development Consultant to support the design, build-out, and configuration of SharePoint-based program management ...

BigHat Biosciences

SharePoint Consultant

San Mateo, CA · On-site +1

BigHat Biosciences is looking for an experienced and detail-oriented SharePoint Development Consultant to support the design, build-out, and configuration of SharePoint-based program management ...

BigHat Biosciences

SharePoint Consultant

San Mateo, CA · On-site +1

BigHat Biosciences is looking for an experienced and detail-oriented SharePoint Development Consultant to support the design, build-out, and configuration of SharePoint-based program management ...

BigHat

Senior Director, Clinical Operations

San Mateo, CA · On-site

$275 - $295/hr

What BigHat Offers: * Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived) * Dental, and vision coverage through Guardian * Additional well‑being ...

previous page

Showing results 41-58

All JobsBighat Jobs

Senior Scientist I, Antibody Engineering

BigHat Biosciences

San Mateo, CA

$160K - $185K/yr

Full-time

Posted 21 days ago

Job description

The role: BigHat Biosciences is seeking an exceptional individual for a Senior Scientist I role on the antibody engineering & binder generation team to serve as a program team lead of therapeutic programs with external and internal partners, driving antibody discovery, design, optimization, and characterization.
  • Lead cross-functional project teams (including Data Science, AI/ML, Engineering, Protein Sciences, Automation) on the execution of rapid, iterative multi-objective optimization to identify high-value therapeutic antibodies through gold-standard assays.
  • Deeply understand target biology to better design antibodies that meet our candidate profile.
  • Contribute expertise in antibody engineering approaches (including humanization, liability remediation, affinity tuning, format engineering, etc) to generate and optimize novel antibodies that meet design requirements.
  • Collaborate closely with BigHat leadership and other cross-functional team members to ensure a tight linkage between strategy, research, and development components.
  • Lead in-depth data analysis of each design cycle to better leverage experimental and computational approaches to reach our design goals.
  • Effectively and regularly communicate results to key decision makers, the broader BigHat team, and to external partners.
  • Ph.D. in biochemistry, structural biology, protein engineering, or related fields.
  • 5+ years of advanced research experience in an industry setting. 
  • Hands-on protein engineering expertise, including structure-guided design, affinity maturation, stability/developability optimization, and rational or computational approaches to antibody engineering.
  • Experience working with diverse antibody formats such as complex multispecifics, T-cell engagers, antibody fragments, antibody-drug conjugates, etc.
  • Expertise in mammalian cell culture, immunoassay, molecular techniques, cell-based assays, protein expression and characterization (e.g., kinetics, SEC). 
  • Exceptional written, verbal, and visual communication skills. 
  • Experience presenting and communicating strategy and results to internal and external partners.  
  • Scientific track record and publication record.
  • Strong data analysis and interpretation skills. Experience working with agentic software tools is a plus. 
The salary estimated for this position is $160,000 - $185,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.

Apply