Job Summary:
BillionToOne is a next-generation molecular diagnostics company focused on transforming healthcare through innovative genomic solutions. They are seeking a Senior Scientist in Oncology to develop AI-powered tools and analytical approaches that leverage genomic and clinical data for actionable insights in precision medicine.
Responsibilities:
• Leverage BillionToOne’s integrated datasets of Northstar genomic sequencing results and real-world clinical data from patients we serve to generate clinically meaningful insights and real-world evidence (RWE).
• Develop AI and machine learning approaches that uncover patterns across genomic alterations, treatment histories, and patient outcomes, supporting internal research and improving how genomic test results inform clinical decision-making.
• Develop AI-powered tools that enhance the clinical utility of BillionToOne’s diagnostics, including systems that surface relevant medical records, literature evidence, clinical trials, and guideline information alongside Northstar test results to assist oncologists in making more personalized treatment decisions.
Qualifications:
Required:
• PhD in biology, biomedical sciences, medicine, computational biology, biomedical informatics, or a related field is required.
• Deep understanding of genomic data, oncology biology, and clinical medical data.
• Experience applying AI, machine learning, or advanced analytics to biomedical or healthcare datasets.
• Strong programming and data science skills (Python and modern ML frameworks).
• Experience working with real-world clinical datasets (EHR, clinical records, registries, or similar).
• Ability to analyze and integrate multimodal biomedical datasets, including genomics, clinical data, and biomedical literature.
• Strong problem-solving skills and ability to collaborate across interdisciplinary teams, including clinical, bioinformatics, and product groups.
Preferred:
• Experience working with oncology real-world datasets.
• Experience applying large language models (LLMs) or retrieval-based AI systems to biomedical knowledge extraction.
• Experience integrating genomic sequencing data with clinical outcomes data.
• Track record of research publications or applied AI systems in healthcare or life sciences.
Company:
BillionToOne is a precision diagnostics company that focuses on genetic testing for disease detection. Founded in 2016, the company is headquartered in Menlo Park, USA, with a team of 501-1000 employees. The company is currently Late Stage.