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Hybridoma Jobs (NOW HIRING)

LanceSoft Inc

Research Associate-I

Spring House, PA

$17.25 - $23.75/hr

Experience with assays using purified immune cells, T-cell culture, and hybridoma generation would be ideal. The candidate should have a good understanding of immunology and/or cell biology, be able ...

TekWissen LLC

Formulation Scientist

Carlsbad, CA · On-site

$23 - $25/hr

Purify monoclonal antibodies from hybridoma cultures using affinity chromatography. * Produce fluorescently labeled bioconjugates. * Maintain a clean, safe, and compliant laboratory and production ...

Werfen

Monoclonal Production Technologist

Norcross, GA · On-site

As a Monoclonal Production Technologist, you will play a key role in the on-going planned maintenance of Hybridoma cell cultures in accordance to established procedures. You will also coordinate ...

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How much do hybridoma jobs pay per hour?

As of Aug 19, 2026, the average hourly pay for hybridoma in the United States is $56.32, according to ZipRecruiter salary data. Most workers in this role earn between $43.99 and $67.31 per hour, depending on experience, location, and employer.

What is a hybridoma?

A Hybridoma job typically involves working with hybridoma technology to produce monoclonal antibodies for research, diagnostic, or therapeutic applications. Responsibilities may include cell culture maintenance, antibody screening, cloning, and production optimization. Professionals in this role often work in biotech or pharmaceutical companies, research institutions, or diagnostic labs. Strong skills in cell biology, immunology, and laboratory techniques are essential for success in this field.

What are the typical daily responsibilities of a hybridoma specialist?

As a Hybridoma Specialist, your daily responsibilities often include maintaining and monitoring hybridoma cell cultures, performing antibody screening assays such as ELISA, and subcloning positive cell lines for further development. You will also prepare and analyze samples, keep detailed laboratory records, and collaborate with researchers to optimize monoclonal antibody production. The role may require troubleshooting cell growth or antibody yield issues and ensuring compliance with laboratory protocols. Working closely with cross-functional teams, such as molecular biologists and quality control specialists, is also a frequent part of the job.

What are the key skills and qualifications needed to thrive in the hybridoma position?

To thrive as a Hybridoma Specialist (commonly referred to as a Hybridoma Scientist or Technician), you need a solid background in cell culture, immunology, and molecular biology, typically supported by a degree in life sciences or related fields. Hands-on experience with monoclonal antibody production, ELISA, flow cytometry, and aseptic techniques, as well as familiarity with laboratory information management systems (LIMS), is highly valuable. Strong attention to detail, analytical thinking, and effective teamwork are key soft skills for success in this position. These abilities are critical to ensure the reliable development of monoclonal antibodies and maintain high standards in research or bioproduction settings.

What are hybridomas employed for?

Hybridomas are used to produce monoclonal antibodies, which are essential in research, diagnostics, and therapeutic applications. The process involves fusing antibody-producing B cells with myeloma cells to create cell lines that generate specific antibodies consistently.
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hybridoma jobs near you
Infographic showing various Hybridoma job openings in the United States as of August 2026, with employment types broken down into 88% Full Time, 4% Temporary, and 8% Contract. Highlights an 100% In-person job distribution, with an average salary of $117,151 per year, or $56.3 per hour.

Research Associate, Upstream Antibody Discovery

Twist Bioscience

Quincy, MA

Full-time

Re-posted 7 days ago

Twist Bioscience rating

7.7

Company rating: 7.7 out of 10

Based on 7 frontline employees who took The Breakroom Quiz

Job description

Research Associate, Upstream Antibody DiscoveryJob DescriptionWe seek a Research Associate to support in vivo antibody discovery using our
high-throughput hybridoma process. In this lab-based role, attention to detail, strong
documentation and communication skills, and working independently and in group settings
will be critical for success. You will work directly with the Upstream Antibody Discovery team on
various projects to produce and scale hybridoma cell lines while supporting
the recombinant expression of antibodies and antigens. 
What You'll Be Doing
Hybridoma generation, culture, scale-up, cryopreservation, and antibody production
Mammalian cell culture
Transient transfections in mammalian cells to support recombinant expression of
antibodies and antigens at a range of scales
Media and buffer preparation
Management of antibody discovery project timelines and deliverables
Cross-functional coordination of workflows within the lab and with project managers
Troubleshooting and continuous process improvement
What You'll Bring to the Team
Bachelor's degree in a scientific discipline required
Prior laboratory experience is strongly preferred, with priority toward experience in an
industry setting
Mammalian cell culture experience with excellent aseptic technique
Knowledge of antibody discovery processes a plus, with a preference toward
understanding hybridoma-based workflows
Ability to troubleshoot scientific processes
Excellent written and verbal communication skills
Highly organized, detail-oriented, and able to operate in a fast-paced environment
About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as "writing" DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

 
 
 
 
 
 
 
 
 
 
 

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