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Work From Home Software Engineer Jobs in Worcester, MA

micro1 AI

Bioinformatics Software Engineer

Worcester, MA · Remote

$80 - $110/hr

Your work will shape how models learn, reason, and perform through high-quality, real-world input. No prior experience in AI is required -- your domain knowledge is what matters. Scope of Work

Varsity Tutors

Software Tutor

Waltham, MA · Remote

$18 - $40/hr

All from the comfort of your home. Why Join Our Platform? * Earn incrementally higher pay for each ... Deep knowledge of software development methodologies, programming languages, version control ...

Varsity Tutors

Software Tutor

Newton, MA · Remote

$18 - $40/hr

All from the comfort of your home. Why Join Our Platform? * Earn incrementally higher pay for each ... Deep knowledge of software development methodologies, programming languages, version control ...

BIRDSVUE LLC

Full Stack AI Engineer

Dunstable, MA · Remote

$60 - $70/hr

... applications from concept to deployment. You will work directly with product leadership and ... Strong understanding of software engineering best practices, testing, CI/CD, and Agile development.

WAHVE

Personal Lines Account Manager - REMOTE

Milford, MA · Remote

$25 - $26/hr

Apply Link - Put your Insurance Experience to work - FROM HOME! At WAHVE , we value significant insurance experience and want to revolutionize the way people think about phasing into retirement by ...

WAHVE

Agency Bookkeeper - REMOTE

Milford, MA · Remote

$27 - $30/hr

Apply Link - Put your Insurance Experience to work - FROM HOME!  At WAHVE , we value significant insurance experience and want to revolutionize the way people think about phasing into ...

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All JobsSoftware Engineer JobsWork From Home Software Engineer JobsWork From Home Software Engineer Jobs in Worcester, MA

Work From Home Software Engineer information

See Worcester, MA salary details

$63.4K

$147.2K

$205.1K

How much do work from home software engineer jobs pay per year?

As of Aug 18, 2026, the average yearly pay for work from home software engineer in Worcester, MA is $147,202.00, according to ZipRecruiter salary data. Most workers in this role earn between $119,700.00 and $172,600.00 per year, depending on experience, location, and employer.

What is a work from home software engineer?

A Work From Home Software Engineer is a professional who designs, develops, tests, and maintains software applications while working remotely, typically from their own residence. They collaborate with team members virtually using communication and project management tools. This role requires strong technical skills, self-motivation, and effective time management to deliver high-quality software solutions without being physically present in a traditional office setting.

What does a work from home software engineer do?

Work from home software engineers plan, write, test, and edit software programs and applications. Instead of working in the office, work from home software engineers complete their job duties from home or another remote location with internet connectivity. As a home-based engineer, you may specialize in a particular area, such as applications, databases, operating systems, or computer networks. Your responsibilities include collaborating with other software engineers to determine the scope and function of the program so that it meets the client's expectations. Then you develop the application using coding language and design techniques, making sure you meet the project’s timeline and budget.

What are the key skills and qualifications needed to thrive as a work from home software engineer?

To thrive as a Work From Home Software Engineer, you need strong programming skills, a solid understanding of software development methodologies, and typically a degree in computer science or related field. Familiarity with version control systems like Git, remote collaboration tools such as Slack or Zoom, and experience with relevant frameworks or cloud platforms are commonly required. Excellent problem-solving abilities, self-motivation, and clear written and verbal communication skills help you stand out in this remote role. These competencies are crucial for delivering high-quality software, collaborating effectively across distributed teams, and maintaining productivity outside a traditional office environment.

How do work from home software engineers typically collaborate with remote teams to ensure project success?

Work From Home Software Engineers frequently use a combination of collaboration tools such as Slack, Jira, and GitHub to stay connected with their teams and manage tasks. Regular virtual meetings, daily stand-ups, and code reviews are common practices to maintain communication and align on project goals. Successful engineers proactively communicate progress and challenges, participate in pair programming sessions, and document their work thoroughly to keep everyone on the same page. Emphasizing transparency and responsiveness helps foster trust and productivity in a remote work setting.

What is the difference between Work From Home Software Engineer vs Remote Software Developer?

AspectWork From Home Software EngineerRemote Software Developer
CredentialsBachelor's in CS or related field, coding certificationsBachelor's in CS or related field, coding certifications
Work EnvironmentHome office, virtual collaboration toolsHome office, virtual collaboration tools
Industry UsageTech companies, startups, IT firmsTech companies, startups, IT firms
Search & ComparisonCommonly searched for job roles with similar responsibilitiesOften compared for remote coding roles

Both roles typically require similar credentials and work environments, focusing on remote software development. The main difference lies in terminology preference; 'Work From Home Software Engineer' emphasizes the employment status, while 'Remote Software Developer' highlights the location flexibility. Both are in high demand across tech industries and often searched interchangeably by job seekers.

More about Work From Home Software Engineer jobs

What are popular job titles related to Work From Home Software Engineer jobs in Worcester, MA?

For Work From Home Software Engineer jobs in Worcester, MA, the most frequently searched job titles are:

What job categories do people searching Work From Home Software Engineer jobs in Worcester, MA look for?

The top searched job categories for Work From Home Software Engineer jobs in Worcester, MA are:

What cities near Worcester, MA are hiring for Work From Home Software Engineer jobs?

Cities near Worcester, MA with the most Work From Home Software Engineer job openings:

Work From Home Software Engineer jobs near you
Infographic showing various Work From Home Software Engineer job openings in Worcester, MA as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% Remote job distribution, with an average salary of $147,202 per year, or $70.8 per hour.

Bioinformatics Software Engineer

micro1 AI

Worcester, MA • Remote

$80 - $110/hr

Part-time

Posted 15 days ago

Job description

Role Title: Computational Biology & Cheminformatics Expert


Role Type: Contractor


Location: Remote


micro1 is engaging Computational Biology & Cheminformatics Experts to contribute their expertise to a customer’s computational drug discovery project. In this role, you'll apply your expertise to help train next-generation AI systems. Your work will shape how models learn, reason, and perform through high-quality, real-world input. No prior experience in AI is required — your domain knowledge is what matters.


Scope of Work

  1. Analyze and interpret small-molecule and drug discovery datasets using advanced computational biology, bioinformatics, and cheminformatics methods.
  2. Curate, annotate, and validate chemical and biological datasets (e.g., ChEMBL, PubChem, DrugBank) to support AI-driven discovery platforms.
  3. Evaluate compound-target interactions, ADMET properties, and lead optimization strategies by integrating chemical, biological, and clinical data sources.
  4. Provide expert insights on structure-activity and structure-property relationships (SAR/SPR), medicinal chemistry approaches, and experimental design considerations.
  5. Build and implement code-based benchmark tasks (e.g., terminal/CLI-based environments) that reflect realistic computational drug discovery scenarios.
  6. Develop reproducible environments (e.g., using Docker) and automated testing pipelines to ensure task correctness and solvability.
  7. Assess and review AI-generated outputs for scientific rigor, accuracy, and practical relevance, delivering detailed written feedback and recommendations.


Preferred Qualifications

  1. Advanced expertise in Computational Biology, Cheminformatics, Medicinal Chemistry, Biochemistry, or related fields; advanced degree (PhD, MSc, PharmD) highly valued but not strictly required.
  2. Strong coding proficiency in Python (beyond analysis scripts), with hands-on experience building tools, pipelines, or testable code; familiarity with Git, GitHub, and Docker.
  3. Extensive experience with cheminformatics toolkits and platforms such as RDKit, KNIME, Schrödinger, OpenEye, or MOE.
  4. Proven track record in small-molecule drug discovery, SAR/QSAR evaluation, ADMET prediction, or virtual screening workflows.
  5. Comfort working with public chemical and bioactivity databases and integrating diverse datasets for scientific analysis.
  6. Demonstrated ability to clearly communicate complex chemical and biological concepts in written feedback and reports.
  7. Experience participating in multidisciplinary and/or remote projects; familiarity with AI-assisted coding tools is a plus.

Apply